Kristien Boelaert

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Publications

  1. Published

    Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin

    Rachel Spruce, Martin Read, Neil Sharma, Rachel Fletcher, Hisham Mehanna, Kristien Boelaert, Vicki Smith & Christopher McCabe, Dec 2016, In : The Journal of clinical endocrinology and metabolism. 101, 12, p. 4551-4563

    Research output: Contribution to journal › Article

  2. Published

    Iodine status of UK schoolgirls: a cross-sectional survey

    Roger Holder, Kristien Boelaert & Jayne Franklyn, 1 Jun 2011, In : Lancet. 377, 9782, p. 2007-2012 6 p.

    Research output: Contribution to journal › Article

  3. Published

    Risk of incident circulatory disease in patients treated for differentiated thyroid carcinoma with no history of cardiovascular disease

    Kristien Boelaert & Krishnarajah Nirantharakumar, 1 Aug 2019, In : Clinical Endocrinology. 91, 2, p. 323-330 8 p.

    Research output: Contribution to journal › Article

  4. Published

    Patients treated for hyperthyroidism are at increased risk of becoming obese: findings from a large prospective secondary care cohort

    Barbara Torlinska, Linda Nichols, Christopher McCabe & Kristien Boelaert, 15 Oct 2019, In : Thyroid. 29, 10, p. 1380-1389 10 p.

    Research output: Contribution to journal › Article

  5. Published

    Iodine Status during Pregnancy in a Region of Mild-to-Moderate Iodine Deficiency is not Associated with Adverse Obstetric Outcomes; Results from the Avon Longitudinal Study of Parents and Children (ALSPAC)

    Barbara Torlinska, Kristien Boelaert, 1 Mar 2018, In : Nutrients. 10, 3, 291.

    Research output: Contribution to journal › Article

  6. Published

    Dimerization of the sodium/iodide symporter

    Alice Fletcher, Jonathan Wolf Mueller, David Hodson, Kristien Boelaert, Martin Read, Vicki Smith & Christopher McCabe, Oct 2019, In : Thyroid. 29, 10, p. 1485-1498 14 p.

    Research output: Contribution to journal › Article

  7. Published

    Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study

    Rasiah Thayakaran, Nicola Adderley, Barbara Torlinska, Kristien Boelaert, Dana Sumilo, Malcolm Price, G Neil Thomas & Krishnarajah Nirantharakumar, 3 Sep 2019, In : BMJ. 366, 8 p., l4892.

    Research output: Contribution to journal › Article

  8. Published

    Controlled Antenatal Thyroid Study: Obstetric Outcomes

    Kristien Boelaert, Shiaoyng Chan, 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O1.

    Research output: Contribution to journal › Abstract

  9. Published

    Liothyronine cost and prescriptions in England

    Kristien Boelaert, 1 Jan 2019, In : The Lancet Diabetes and Endocrinology. 7, 1, p. 11-12 2 p.

    Research output: Contribution to journal › Letter

  10. Published

    Iodothyronine deiodinase enzyme mRNA expression in normal pituitary and pituitary adenomas

    Lesley Tannahill, Christopher McCabe, Kachilele-Linjewile Kachilele, Kristien Boelaert, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jan 2001.

    Research output: Contribution to conference (unpublished) › Paper

  11. Published

    Dysregulation of iodothyronine deiodinase enzyme expression and function in human pituitary tumours

    Lesley Tannahill, Christopher McCabe, Kachilele-Linjewile Kachilele, Kristien Boelaert, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jun 2002, In : Clinical Endocrinology. 56, 6, p. 735-743 9 p.

    Research output: Contribution to journal › Article

  12. Published

    PTTG upregulates its binding factor PBF in vitro

    Farhat Khanim, Kristien Boelaert, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2003, p. P131.

    Research output: Contribution to conference (unpublished) › Abstract

  13. Published

    PTTG Binding Factor (PBF) - a Novel Transforming Gene in Thyroid Tumorigenesis

    Kristien Boelaert, Lesley Tannahill, Dae Kim, Margaret Eggo, Neil Gittoes, Lawrence Young, Jayne Franklyn & Christopher McCabe, 5 Apr 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 7, p. 4341-4349 9 p.

    Research output: Contribution to journal › Article

  14. Published

    PTTG binding factor (PBF) - A novel transforming gene in thyroid tumorigenesis which represses iodide uptake

    Kristien Boelaert, Lesley Tannahill, Margaret Eggo, Jayne Franklyn, Neil Gittoes & Christopher McCabe, 1 Jan 2004, p. OR 37-3.

    Research output: Contribution to conference (unpublished) › Abstract

  15. Published

    PTTG binding factor (PBF) - a novel transforming gene in thyroid tumorigenesis which represses iodide uptake

    Kristien Boelaert, Lesley Tannahill, Margaret Eggo, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2005, p. OC37.

    Research output: Contribution to conference (unpublished) › Abstract

  16. Published

    PTTG binding factor in thyroid cancer

    Kristien Boelaert, Farhat Khanim, Dae Kim & Jayne Franklyn, 1 Jan 2003, p. 93. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  17. Published

    PTTG binding factor (PBF) can transform cells independently of interaction with PTTG

    Kristien Boelaert, Dae Kim, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P492.

    Research output: Contribution to conference (unpublished) › Abstract

  18. Published

    PBF predicts recurrence in thyroid cancer and potentiates the actions of PTTG in vitro

    Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 1 Jan 2004, p. OC19.

    Research output: Contribution to conference (unpublished) › Abstract

  19. Published

    Pituitary Tumor Transforming Gene Binding Factor: A New Gene in Breast Cancer

    Rachel Spruce, Martin Read, Vicki Smith, Neil Sharma, Laura Buckley, Margaret Eggo, Laurence Loubiere, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 May 2010, In : Cancer Research. 70, 9, p. 3739-3749 11 p.

    Research output: Contribution to journal › Article

  20. Published

    A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer

    Vicki Smith, Martin Read, Andrew Turnell, Rachel Spruce, Jim Fong, Margaret Eggo, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 1 Sep 2009, In : Journal of Cell Science. 122, 18, p. 3393-3402 10 p.

    Research output: Contribution to journal › Article

  21. Published

    Manipulation of PBF/PTTG1IP phosphorylation status ; a potential new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors

    Vicki Smith, Neil Sharma, Rachel Spruce, Martin Read, Ashley Martin, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jul 2013, In : The Journal of clinical endocrinology and metabolism. 98, 7, p. 2876-2886 11 p.

    Research output: Contribution to journal › Article

  22. Published

    Repression of the human NIS upstream enhancer (hNUE) by PTTG and PBF

    Vicki Smith, Kristien Boelaert, Sally James, Jayne Franklyn & Christopher McCabe, 1 Jan 2006.

    Research output: Contribution to conference (unpublished) › Abstract

  23. Published

    Repression of the human NIS upstream enhancer (hNUE) by PTTG

    Vicki Smith, Kristien Boelaert, Sally James, Margaret Eggo, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P906.

    Research output: Contribution to conference (unpublished) › Abstract

  24. Published

    Repression of the human upsteam enhancer (hNUE) by TTG and PBF

    Vicki Smith, Kristien Boelaert, Sally James, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P16.

    Research output: Contribution to conference (unpublished) › Abstract

  25. Published

    The Sodium Iodide Symporter (NIS) is Repressed by PTTG via the Human NIS Upstream Enhancer (hNUE)

    Vicki Smith, Kristien Boelaert, Sally James, Jayne Franklyn & Christopher McCabe, 1 Jan 2007.

    Research output: Contribution to conference (unpublished) › Abstract

  26. Accepted/In press

    The prevalence of thyroid dysfunction and autoimmunity in women with history of miscarriage or subfertility

    Rima Smith, Aurelio Tobias Garces, Paul Smith, Lee Middleton, Justin Chu & 14 others, , Mark Kilby, Jane Daniels, Shakila Thangaratinam, Shiaoyng Chan, Kristien Boelaert & Arri Coomarasamy, 19 May 2020, (Accepted/In press) In : Journal of Clinical Endocrinology and Metabolism.

    Research output: Contribution to journal › Article

  27. Published

    PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8

    Vicki Smith, Martin Read, Andrew Turnell, Jim Fong, Shiaoyng Chan, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2012, In : Endocrinology. 153, 7, p. 3526-36 11 p.

    Research output: Contribution to journal › Article

  28. Published

    The sodium iodide symporter (NIS) is repressed by PTTG via the human NIS upsteam enhancer (hNUE)

    Vicki Smith, Kristien Boelaert, Sally James, Margaret Eggo, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P489.

    Research output: Contribution to conference (unpublished) › Abstract

  29. Published

    Levothyroxine in women with thyroid peroxidase antibodies before conception

    Rima Smith, Lee Middleton, Versha Cheed, Christopher McCabe & 14 others, , Alex Tan, Mark Kilby, Kristien Boelaert, Jane Daniels, Shakila Thangaratinam & Arri Coomarasamy, 4 Apr 2019, In : The New England Journal of Medicine. 380, 14, p. 1316-1325 10 p.

    Research output: Contribution to journal › Article

  30. Published

    Who Should Treat Thyroid Cancer? A UK Surgical Perspective

    Neil Sharma, Kristien Boelaert, 1 Aug 2010, In : Clinical Oncology. 22, 6, p. 413-418 6 p.

    Research output: Contribution to journal › Article

  31. Published

    Drug repurposing identifies inhibitors of the proteostasis network to augment radioiodine uptake in combinatorial approaches targeting thyroid cancer

    Martin Read, Alice Fletcher, Hannah Nieto, Holly Adcock, Liam Cox, Luke Alderwick, Kristien Boelaert, Vicki Smith & Christopher McCabe, 8 May 2020, In : Journal of the Endocrine Society. 4, Issue Supplement 1, 1 p., OR28-03.

    Research output: Contribution to journal › Abstract

  32. Published

    Distinct p53 response profiles in transgenic mouse models of thyroid-specific PBF and PTTG expression

    Martin Read, Neil Sharma, Vicki Smith, Kristien Boelaert & Christopher McCabe, Nov 2015, In : Endocrine Abstracts. 38, P149.

    Research output: Contribution to journal › Abstract

  33. Published

    PTTG-Binding Factor (PBF) induces hyperplastic lesions in thyroids of aged mice

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2011.

    Research output: Contribution to conference (unpublished) › Paper

  34. Published

    Thyroid hyperplasia in a transgenic mouse model of PTTG-Binding Factor (PBF) overexpression

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Margaret Eggo, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Sep 2010.

    Research output: Contribution to conference (unpublished) › Abstract

  35. Published

    Enlargement of the thyroid gland in a heterozygous PBF knock-in transgenic mouse model

    Martin Read, Jim Fong, Vicki Smith, Andrew Turnell, Wendy Leadbeater, Dae Kim, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009, p. 371. 1 p.

    Research output: Contribution to conference (unpublished) › Paper

  36. Published

    Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer

    Martin Read, Hannah Nieto, Alice Fletcher, Neil Sharma, Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2

    Research output: Contribution to journal › Abstract

  37. Published

    Dietary factors augment the ability of the proto-oncogene PBF to induce goitrogenesis and hyperplasia in vivo

    Martin Read, Vicki Smith, Jim Fong, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2012, In : Endocrine Abstracts. 28, OC3.8.

    Research output: Contribution to journal › Abstract

  38. Published

    Proto-oncogene PBF/PTTG1IP Regulates Thyroid Cell Growth and Represses Radioiodide Treatment

    Martin Read, Jim Fong, Neil Sharma, Vicki Smith, Margaret Eggo, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Oct 2011, In : Cancer Research. 71, 19, p. 6153-64 12 p.

    Research output: Contribution to journal › Article

  39. Published

    A role for PTTG binding factor (PBF) in goitrogenesis

    Martin Read, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009.

    Research output: Contribution to conference (unpublished) › Paper

  40. Published

    Comparative analysis of human and mouse expression data identifies distinct proto-oncogene PBF- and PTTG-associated genes in thyroid cancer

    Martin Read, Jim Fong, Hannah Nieto, Kristien Boelaert, Vicki Smith, Andrew Turnell & Christopher McCabe, 1 Jul 2016, In : European Journal of Cancer. 61, Suppl 1, p. S36 1 p., 202.

    Research output: Contribution to journal › Abstract

  41. Published

    A novel mechansim of thyroid tumourigenesis based on inactivation of p53 by the PTTG-binding factor PBF

    Martin Read, Rachel Spruce, Andrew Turnell, Dae Kim, Vicki Smith, Jim Fong, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 12 Apr 2008, In : Cancer Research. 68, p. 1855

    Research output: Contribution to journal › Abstract

  42. Published

    Elevated genetic instability is associated with repressed DNA repair gene expression in a bi-transgenic murine model of PTTG and PBF

    Martin Read, Jim Fong, Vicki Smith, Rachel Spruce, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2 Dec 2013.

    Research output: Contribution to conference (unpublished) › Poster

  43. E-pub ahead of print

    Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer

    Martin Read, Alice Fletcher, Hannah Nieto, John Reynolds, Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 15 May 2017, In : Oncogene. 72326.

    Research output: Contribution to journal › Article

  44. Published

    PO-124 PTTG and PBF functionally interact with P53 and predict overall survival in head and neck cancer

    Martin Read, Alice Fletcher, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Jul 2018, In : ESMO Open. 3, Suppl. 2, p. A69-A69 1 p.

    Research output: Contribution to journal › Abstract

  45. Published

    Examination of PTTG-Binding Factor (PBF) mRNA reveals functional miRNA target sites and exon-skipping splice variants in thyroid cells

    Martin Read, Alice Fletcher, Vicki Smith, Rachel Spruce, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Mar 2014, In : Endocrine Abstracts. 34, P397.

    Research output: Contribution to journal › Abstract

  46. Published

    Yellow fluorescent protein (YFP) as a biosensor for intracellular iodide in thyroid cancer cells

    Martin Read, Alice Fletcher, Kristien Boelaert, Vicki Smith & Christopher McCabe, 15 May 2018.

    Research output: Contribution to conference (unpublished) › Abstract

  47. Published

    The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells

    Martin Read, Jim Fong, Rachel Spruce, Vicki Smith, Neil Sharma, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Apr 2014, In : Endocrinology. 155, 4, p. 1222-34 13 p.

    Research output: Contribution to journal › Article

  48. Published

    Elevated genetic instability is associated with repressed DNA repair gene expression in a bi-transgenic murine model of PTTG and PBF

    Martin Read, Jim Fong, Vicki Smith, Rachel Spruce, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 2013, p. A24.

    Research output: Contribution to conference (unpublished) › Abstract

  49. Published

    A high-throughput yellow fluorescent protein (YFP) cell-based screen identifies autophagy modulators to increase the effectiveness of radioiodine therapy

    Martin Read, Alice Fletcher, Luke Alderwick, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 Nov 2019, In : Endocrine Abstracts. 65, 1 p., OC4.1.

    Research output: Contribution to journal › Abstract

  50. Published

    Evidence of a role for the PTTG binding protein (PBF) in goitrogenesis

    Martin Read, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2009.

    Research output: Contribution to conference (unpublished) › Paper

  51. Published

    Comparative analysis of human and mouse expression data identifies proto-oncogene PTTG- and PBF-associated genes in thyroid cancer

    Martin Read, Hannah Nieto, Alice Fletcher, Neil Sharma, Andrew Turnell, Kristien Boelaert, Vicki Smith & Christopher McCabe, 13 May 2016.

    Research output: Contribution to conference (unpublished) › Abstract

  52. Published

    Akt activation in a murine thyroid goitre model induced by the tumourigenic factor PBF

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2010.

    Research output: Contribution to conference (unpublished) › Paper

  53. E-pub ahead of print

    PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer

    Martin Read, Alice Fletcher, Peter Rae, Hannah Nieto, Sally Roberts, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 28 Aug 2018, In : Cancer Research. 25 p.

    Research output: Contribution to journal › Article

  54. Published

    High tumoral expression of PBF and PTTG modulates the DNA damage response and is associated with poor survival in thyroid cancer

    Martin Read, Jim Fong, Alice Fletcher, Neil Sharma, Kristien Boelaert, Andrew Turnell, Vicki Smith & Christopher McCabe, 4 Nov 2016, In : Endocrine Abstracts. 44, P246.

    Research output: Contribution to journal › Abstract

  55. Published

    The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer

    Martin Read, Vicki Smith, Rachel Spruce, Dae Kim, Stephen Ward, Kristien Boelaert, Jayne Franklyn, Andrew Turnell & Christopher McCabe, Jan 2016, In : Molecular Carcinogenesis. 55, 1, p. 15-26

    Research output: Contribution to journal › Article

  56. Published

    PTTG-Binding Factor (PBF) induces goitrogenesis and represses iodide uptake in vivo

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Jan 2011.

    Research output: Contribution to conference (unpublished) › Paper

  57. Published

    The PTTG-Binding Factor (PBF) induces thyroid hyperplastic lesions in aged mice

    Martin Read, Neil Sharma, Jim Fong, Vicki Smith, Wendy Leadbeater, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 1 Oct 2010.

    Research output: Contribution to conference (unpublished) › Abstract

  58. Published

    Oncogenic action of pituitary-tumor transforming gene (PBF) in head and neck cancer is associated with poorer overall survival

    Martin Read, Alice Fletcher, Hannah Nieto, Moray Campbell, Kristien Boelaert, Andrew Turnell, Vicki Smith, Hisham Mehanna & Christopher McCabe, 1 Nov 2018, In : Endocrine Abstracts. 59, 1 p., P119.

    Research output: Contribution to journal › Abstract

  59. Published

    Abnormal expression of 11beta-HSD type 2 in human pituitary adenomas: a prereceptor determinant of pituitary cell proliferation

    Elizabeth Rabbitt, John Ayuk, Kristien Boelaert, Michael Sheppard, Martin Hewison, Paul Stewart & Neil Gittoes, 20 Mar 2003, In : Oncogene. 22(11), 11, p. 1663-1667 5 p.

    Research output: Contribution to journal › Article

  60. Published

    Pharmacological enhancement of radioiodine uptake using Src kinase inhibitors

    Alice Fletcher, Neil Sharma, Martin Read, Kristien Boelaert, Christopher McCabe & Vicki Smith, 13 Feb 2017, In : Thyroid Research. 10(Suppl 1), 2, p. 2 1 p., O2.

    Research output: Contribution to journal › Abstract

  61. Published

    Separase, securin and Rad21 in neural cell growth

    Jayne Franklyn, Kristien Boelaert, Shiaoyng Chan, Dae Kim, Mark Kilby & Christopher McCabe, 1 Oct 2007, In : Journal of Cellular Physiology. 213, 1, p. 45-53 9 p.

    Research output: Contribution to journal › Article

  62. Published

    Separase and Securin; Their Roles in the Developing Human Fetal Brain

    Kristien Boelaert, Mark Kilby, Jayne Franklyn & Christopher McCabe, 1 Jan 2005.

    Research output: Contribution to conference (unpublished) › Paper

  63. Published

    Separase and securing; their roles in the developing human fetal brain

    Kristien Boelaert, Mark Kilby, Jayne Franklyn & Christopher McCabe, 1 Jan 2005, p. P62.

    Research output: Contribution to conference (unpublished) › Abstract

  64. Published

    The key mitotic regulators securin and separase in the human fetal brain

    Kristien Boelaert, Dae Kim, Lesley Tannahill, Farhat Khanim, Neil Gittoes, Jayne Franklyn, Mark Kilby & Christopher McCabe, 1 Jan 2004, p. P3-350.

    Research output: Contribution to conference (unpublished) › Abstract

  65. Published

    RAD21 dependent effects of securin and separase on fetal neuronal cells

    Christopher McCabe, Kristien Boelaert, Dae Kim, Shiaoyng Chan, Jayne Franklyn & Mark Kilby, 1 Jan 2006.

    Research output: Contribution to conference (unpublished) › Abstract

  66. Published

    Separase and Securin; Their Roles in the Developing Human Fetal Brain

    Kristien Boelaert, Mark Kilby, Jayne Franklyn & Christopher McCabe, 1 Jan 2005, p. P62.

    Research output: Contribution to conference (unpublished) › Abstract

  67. Published

    RAD21-dependent effects of securin/PTTG and separase on fetal neuronal NT2 cells

    Kristien Boelaert, Dae Kim, Shiaoyng Chan, Mark Kilby, Jayne Franklyn & Christopher McCabe, 1 Jan 2006, p. P408.

    Research output: Contribution to conference (unpublished) › Abstract

  68. Published

    Antigen-specific immunotherapy with thyrotropin receptor peptides in Graves' hyperthyroidism: a phase I study

    Kristien Boelaert, 17 Jul 2019, In : Thyroid. 29, 7, p. 1003-1011 9 p.

    Research output: Contribution to journal › Article

  69. Published

    Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee

    Kristien Boelaert, Christopher McCabe, Vicki Smith, 23 May 2015, In : Clinical Endocrinology.

    Research output: Contribution to journal › Article

  70. Published

    Thyroid stimulating hormone in thyroid cancer: does it matter?

    Hannah Nieto & Kristien Boelaert, 1 Nov 2016, In : Endocrine-related cancer. 23, 11, ERC-16-0328.

    Research output: Contribution to journal › Article

  71. Published

    Costs and benefits of iodine supplementation for pregnant women in a mildly to moderately iodine-deficient population: a modelling analysis

    Mark Monahan, Kristien Boelaert, Kate Jolly, Shiaoyng Chan, Pelham Barton & Tracy Roberts, Sep 2015, In : The Lancet Diabetes and Endocrinology. 3, 9, p. 715-722 8 p.

    Research output: Contribution to journal › Article

  72. Published

    Differences in the recurrence and mortality outcomes rates of incidental and nonincidental papillary thyroid microcarcinoma: a systematic review and meta-analysis of 21 329 person-years of follow-up

    Hisham Mehanna, Ben Carter, Kristien Boelaert & Jayne Franklyn, Aug 2014, In : The Journal of clinical endocrinology and metabolism. 99, 8, p. 2834-43 10 p.

    Research output: Contribution to journal › Article

  73. Published

    PUG binding factor - a new gene in breast cancer

    Christopher McCabe, Martin Read, Vicki Smith, Laurence Loubiere, Jayne Franklyn, Kristien Boelaert & Christopher McCabe, 2010, In : Endocrine Journal.

    Research output: Contribution to journal › Article

  74. Published

    Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour.

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Shakir Hussain, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Feb 2003, In : Clinical Endocrinology. 58, 2, p. 141-50 10 p.

    Research output: Contribution to journal › Article

  75. Published

    The destruction box of pituitary tumor transforming gene (PTTG) mediates cell transformation in vitro

    Christopher McCabe, Jattinder Khaira, Kristien Boelaert, Lesley Tannahill, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jan 2001, p. OR37-2.

    Research output: Contribution to conference (unpublished) › Paper

  76. Published

    Expression and function of VEGF and its receptor KDR in pituitary tumors

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Michael Sheppard, Neil Gittoes & Jayne Franklyn, 1 Jan 2002, p. P2-231.

    Research output: Contribution to conference (unpublished) › Paper

  77. Published

    Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Jattinder Khaira, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Sep 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 9, p. 4238-4244 7 p.

    Research output: Contribution to journal › Article

  78. Published

    The destruction box PTTG mediates cell transformation

    Christopher McCabe, Lesley Tannahill, Kristien Boelaert, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jan 2002, p. P139.

    Research output: Contribution to conference (unpublished) › Paper

  79. Published

    Pituitary tumor transforming gene (PTTG), PTTG binding factor (PBF) and related growth factor expression in sporadic pituitary tumours

    Christopher McCabe, Jattinder Khaira, Kristien Boelaert, Lesley Tannahill, Michael Sheppard, Jayne Franklyn & Neil Gittoes, 1 Jan 2001, p. OC18.

    Research output: Contribution to conference (unpublished) › Abstract

  80. Published

    Expression and function of VEGF and its receptor in pituitary tumours

    Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Jattinder Khaira, Michael Sheppard, Neil Gittoes & Jayne Franklyn, 1 Jan 2002, p. OC14.

    Research output: Contribution to conference (unpublished) › Paper

  81. Published

    Influences of age, gender, smoking and family history on autoimmune thyroid disease phentotype

    Kristien Boelaert, Stephen Gough & Jayne Franklyn, 26 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 4873-4880 8 p.

    Research output: Contribution to journal › Article

  82. Published

    Lack of association between serum TSH or free T4 and body mass index in euthyroid subjects

    Kristien Boelaert, Michael Sheppard, Roger Holder, Stephen Gough & Jayne Franklyn, 1 Feb 2006, In : Clinical Endocrinology. 64, 2, p. 125-128 4 p.

    Research output: Contribution to journal › Article

  83. Published

    Influence of family history on the age of presentation of AITD - the UK AITD consortium

    Kristien Boelaert, Stephen Gough & Jayne Franklyn, 1 Jan 2006, p. P878.

    Research output: Contribution to conference (unpublished) › Abstract

  84. Published

    The pituitary tumor transforming gene in thyroid cancer

    Neil Sharma, Vicki Smith, Kristien Boelaert & Christopher McCabe, 5 Apr 2012, In : Journal of endocrinological investigation. 35, 4, p. 425-433

    Research output: Contribution to journal › Review article

  85. Published

    Regulation of Pituitary Tumor Transforming Gene (PTTG) expression and phosphorylation in thyroid cells

    Martin Read, Jim Fong, Vicki Smith, Jayne Franklyn, Christopher McCabe & Kristien Boelaert, 18 Jul 2013, In : Endocrinology.

    Research output: Contribution to journal › Article

  86. Published

    Pituitary tumor transforming gene (PTTG) regulates downstream angiogenic genes in thyroid cells

    Dae Kim, Kristien Boelaert, Margaret Eggo, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2004, p. 100. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  87. Published

    Relationship between PTTG expression and genomic instability in differentiated thyroid cancers

    Dae Kim, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 1 Jan 2004.

    Research output: Contribution to conference (unpublished) › Paper

  88. Published

    Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a VEGF/KDR/ID3 autocrine pathway

    Dae Kim, Jayne Franklyn, Kristien Boelaert, Margaret Eggo & Christopher McCabe, 5 Sep 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4603-4611 9 p.

    Research output: Contribution to journal › Article

  89. Published

    Pituitary tumor transforming gene (PTTG) regulates multiple downstream angiogenic genes in thyroid cancer

    Dae Kim, Jayne Franklyn, Kristien Boelaert, Margaret Eggo & Christopher McCabe, 29 Dec 2005, In : Journal of Clinical Endocrinology and Metabolism. 91, 3, p. 1119-1128 10 p.

    Research output: Contribution to journal › Article

  90. Published

    PTTG expression and genomic instability in differentiated thyroid cancer using the FISSR-PCR technique

    Dae Kim, Christopher McCabe, Kristien Boelaert & Jayne Franklyn, 1 Jan 2004.

    Research output: Contribution to conference (unpublished) › Paper

  91. Published

    Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a VEGF/KDR/ID3 autocrine pathway

    Dae Kim, Jayne Franklyn, Kristien Boelaert, Margaret Eggo & Christopher McCabe, 1 Jan 2006, p. P491.

    Research output: Contribution to conference (unpublished) › Abstract

  92. Published

    Pituitary Tumor Transforming Gene (PTTG) Induces Genetic Instability in Thyroid Cells

    Dae Kim, Kristien Boelaert, Victor Lopes, Jayne Franklyn & Christopher McCabe, 9 May 2005, In : Oncogene. 24(30), p. 4861-4866 6 p.

    Research output: Contribution to journal › Article

  93. Published

    PTTG Induces Genomic Instability in Thyroid Cells

    Dae Kim, Kristien Boelaert, Jayne Franklyn & Christopher McCabe, 1 Jan 2005.

    Research output: Contribution to conference (unpublished) › Paper

  94. Published

    PTTG induces genomic instability in thyroid cells

    Dae Kim, Kristien Boelaert, Margaret Eggo, Lesley Tannahill, Jayne Franklyn & Christopher McCabe, 1 Jan 2005, p. OC36.

    Research output: Contribution to conference (unpublished) › Abstract

  95. Published

    Pituitary tumor transforming gene (PTTG) regulates downsteam angiogenic genes in thyroid cells

    Dae Kim, Kristien Boelaert, Margaret Eggo, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2004, p. P3-219.

    Research output: Contribution to conference (unpublished) › Abstract

  96. Published

    PTTG regulates downstream angiogenic genes in thyroid cells

    Dae Kim, Kristien Boelaert, Margaret Eggo, Neil Gittoes, Jayne Franklyn & Christopher McCabe, 1 Jan 2004, p. P100.

    Research output: Contribution to conference (unpublished) › Abstract

  97. Published

    Complex thyroid cancer with likely underlying TSHoma - a medical challenge

    Punith Kempegowda, John Ayuk & Kristien Boelaert, 1 Mar 2017, In : Endocrine Abstracts.

    Research output: Contribution to journal › Article

  98. Published

    Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management

    Kristien Boelaert & Lorraine Harper, 6 May 2019, In : BMC Nephrology. 20, 1, 154.

    Research output: Contribution to journal › Article

  99. Published

    Deiodinase activity and expression in the early human fetal brain

    Kachilele-Linjewile Kachilele, Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Neil Gittoes, Jayne Franklyn & Mark Kilby, 1 Jan 2001, p. 176. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  100. Published

    Deiodinase activity and expression in the first and second trimester human fetal brain

    Kachilele-Linjewile Kachilele, Christopher McCabe, Kristien Boelaert, Lesley Tannahill, Shiaoyng Chan, Neil Gittoes, Jayne Franklyn & Mark Kilby, 1 Jan 2001, p. 3-20. 18 p.

    Research output: Contribution to conference (unpublished) › Paper

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