Kristian Brock

(Former)

Kristian Brock

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ORCID: 0000-0002-3921-0166
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Most downloaded publications

How to design a dose-finding study using the continual reassessment method
Kristian Brock, Christina Yap, 18 Jan 2019, In: BMC Medical Research Methodology. 19, 1, 15 p., 18.

Research output: Contribution to journal › Article › peer-review

255 downloads
Combination Lenalidomide and Azacitidine: A Novel Salvage Therapy in Patients Who Relapse After Allogeneic Stem-Cell Transplantation for Acute Myeloid Leukemia
Charles Craddock, Daniel Slade, Carmela De Santo, Rachel Hoare, Kristian Brock & Christina Yap, 1 Mar 2019, In: Journal of Clinical Oncology . 37, 7, p. 580-588 9 p., JCO1800889.

Research output: Contribution to journal › Article › peer-review

198 downloads
Recommendations for Randomised Trials in Surgical Oncology
James Glasbey, Kristian Brock & Simon Bach, Dec 2017, In: Clinical Oncology. 29, 12, p. 799-810

Research output: Contribution to journal › Article › peer-review

191 downloads
Ibrutinib plus venetoclax in relapsed/refractory chronic lymphocytic leukemia: the CLARITY study
Kristian Brock, Sam Munoz Vicente, Becky Boucher, 20 Oct 2019, In: Journal of Clinical Oncology . 37, 30, p. 2722-2729 8 p.

Research output: Contribution to journal › Article › peer-review

176 downloads
Acquired Isodisomy on Chromosome 13 at diagnosis results in impaired overall survival in Patients with FLT3-ITD mutant Acute Myeloid Leukaemia
Justin Loke, Kristian Brock, Paul Ferguson, Charles Craddock, Michael Griffiths & Manoj Raghavan, 2015, In: Leukemia. 29, 12, p. 2404-2407

Research output: Contribution to journal › Article › peer-review

175 downloads

Recent publications

Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation
Alexander Roberts, Tina Tang, Chiara Pallini, Graham Wallace, Alison Cooper, Aaron Scott, David Thickett, Sebastian Lugg, Thomas Pinkney, Graham Taylor, Kristian Brock, Zania Stamataki, John Curnow, John Gordon, Omar Qureshi, Nicholas Barnes & 7 others, , 17 Feb 2021, In: Scientific Reports. 11, 1, 4030.

Research output: Contribution to journal › Article › peer-review

Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label feasibility study
Feb 2021, In: The Lancet Gastroenterology & Hepatology. 6, 2, p. 92–105 14 p.

Research output: Contribution to journal › Article › peer-review

Bariatric surgery versus community weight management intervention for the treatment of idiopathic intracranial hypertension (IIH:WT): a randomized controlled trial
Magda Aguiar, David Cartwright, Gareth Lavery, Rishi Singhal, Abd Tahrani, Kristian Brock & 2 others, Emma Frew & Alex Sinclair, 30 Jan 2021, (Accepted/In press) In: JAMA Neurology.

Research output: Contribution to journal › Article › peer-review

View all (27)

Recent Activities

Dose-Finding Clinical Trial Designs in Stan

Kristian Brock (Speaker)

30 Aug 2018

Activity: Talk or presentation › Academic conference

A Phase II Clinical Trial with Efficacy and Toxicity Outcomes and Baseline Covariates

Kristian Brock (Speaker), Lucinda Billingham (Contributor), Gary Middleton (Contributor) & Christina Yap (Contributor)

2 Jul 2018

Activity: Talk or presentation › Academic conference

Benefits and limitations of subgroup analyses in oncology trials

Kristian Brock (Invited speaker)

4 May 2018

Activity: Talk or presentation › Invited talk

View all (21)