Jon Frampton

Publications

  1. 2019
  2. Published

    CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex

    Giacomo Volpe, Jon Frampton, 24 Jan 2019, In : Leukemia. 33, p. 1608-1619 12 p.

    Research output: Contribution to journalArticle

  3. 2018
  4. Published
  5. Published
  6. Published
  7. 2017
  8. Published
  9. Published
  10. Published

    Targeting the transcription factor Myb by small-molecule inhibitors

    Jon Frampton, 1 Mar 2017, In : Experimental Hematology. 47, p. 31-35

    Research output: Contribution to journalArticle

  11. 2016
  12. E-pub ahead of print
  13. 2015
  14. E-pub ahead of print
  15. Published

    Fibrin activates GPVI in human and mouse platelets

    Craig Hughes, Jon Frampton & Steve Watson, 24 Sep 2015, In : Blood. 126, 13, p. 1601-1608 8 p.

    Research output: Contribution to journalArticle

  16. Published
  17. Published
  18. Published

    Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development

    Kate Lowe, Brenda Finney, Jon Frampton, Christopher Buckley & Steve Watson, 11 Jun 2015, In : Blood. 125, 24, p. 3769-3777 9 p.

    Research output: Contribution to journalArticle

  19. Published

    Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes

    Paloma Garcia, Jon Frampton, Feb 2015, In : Stem Cells. 33, 2, p. 479-490 12 p.

    Research output: Contribution to journalArticle

  20. Published
  21. 2014
  22. Published

    Transcriptional pause release is a rate-limiting step for somatic cell reprogramming

    Yuan Li & 12 others, , Jon Frampton, 6 Nov 2014, In : Cell stem cell. 15, 5, p. 574-88 15 p.

    Research output: Contribution to journalArticle

  23. Published

    RAG1/2 knockout pigs with severe combined immunodeficiency

    Jon Frampton, 1 Aug 2014, In : Journal of Immunology. 193, 3, p. 1496-503 8 p.

    Research output: Contribution to journalArticle

  24. Published
  25. 2013
  26. Published
  27. Published
  28. Published

    Bioluminescence tomography improves quantitative accuracy for pre-clinical imaging

    Hector Basevi, Hamid Dehghani, Iain Styles & Jon Frampton, 25 Jun 2013, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  29. Published

    C/EBPα and MYB regulate FLT3 expression in AML

    Giacomo Volpe, Paloma Garcia, Emilie Dasse, Laura O'Neill, Jon Frampton & Stephanie Dumon, 23 Jan 2013, In : Leukemia. 27, 7, p. 1487-1496 10 p.

    Research output: Contribution to journalArticle

  30. Published
  31. Published
  32. Published
  33. 2012
  34. Published
  35. Published
  36. Published
  37. Published

    A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

    Jon Frampton, 1 Apr 2012, In : Science. 336, 6077, p. 86-90 5 p.

    Research output: Contribution to journalArticle

  38. Published
  39. Published
  40. 2011
  41. Published
  42. Published

    c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation

    Paloma Garcia & Jon Frampton, 1 Aug 2011, In : Journal of Thrombosis and Haemostasis. 9, 8, p. 1572-1581 10 p.

    Research output: Contribution to journalArticle

  43. Published
  44. Published
  45. Published
  46. Published

    Professor Alan M Gewirtz (1949-2010) OBITUARY

    Jon Frampton, 1 May 2011, In : Oncogene. 30, 19, p. 2187-2187 1 p.

    Research output: Contribution to journalArticle

  47. 2010
  48. Published
  49. Published

    Critical roles for c-Myb in lymphoid priming and early B-cell development

    Jon Frampton, 1 Apr 2010, In : Blood. 115, 14, p. 2796-2805 10 p.

    Research output: Contribution to journalArticle

  50. Published

    Platelets contribute to postnatal occlusion of the ductus arteriosus

    Jon Frampton, 1 Jan 2010, In : Nature Medicine. 16, 1, p. 75-U111

    Research output: Contribution to journalArticle

  51. 2009
  52. Published
  53. Published
  54. Published
  55. Published
  56. Published
  57. Published
  58. 2008
  59. Published

    A dual role for integrin-linked kinase in platelets: regulating integrin function and  -granule secretion

    Jon Frampton, 1 Dec 2008, In : Blood. 112, 12, p. 4523-4531 9 p.

    Research output: Contribution to journalArticle

  60. Published

    Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

    Jon Frampton, 1 Dec 2008, In : Blood. 112, 12, p. 4512-4522 11 p.

    Research output: Contribution to journalArticle

  61. Published
  62. Published
  63. Published
  64. Published

    c-Myb-Dependent Smooth Muscle Cell Differentiation

    Jon Frampton, 14 Mar 2008, In : Circulation Research. 102, 5, p. 554-561 8 p.

    Research output: Contribution to journalArticle

  65. 2007
  66. Published
  67. Published
  68. Published

    c-Myb is required for progenitor cell homeostasis in colonic crypts

    John Heath, Jon Frampton, 6 Mar 2007, In : National Academy of Sciences. Proceedings. 104, 10, p. 3829-34 6 p.

    Research output: Contribution to journalArticle

  69. Published

    Regulation of erythropoiesis by the neuronal transmembrane protein Lrfn2

    Jon Frampton, 1 Jan 2007, In : Experimental Hematology. 35, 5, p. 724-734 11 p.

    Research output: Contribution to journalArticle

  70. 2006
  71. Published
  72. Published

    Targeting an E2F site in the mouse genome prevents promoter silencing in quiescent and post-mitotic cells

    Fiona Tavner, Jon Frampton, 30 Oct 2006, In : Oncogene. 26, 19, p. 2727-35 9 p.

    Research output: Contribution to journalArticle

  73. Published

    Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development

    Jon Frampton, 1 Aug 2006, In : Blood. 108, 3, p. 896-903 8 p.

    Research output: Contribution to journalArticle

  74. Published

    c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells

    Jon Frampton, 1 Jul 2006, In : Blood. 108, 1, p. 297-304 8 p.

    Research output: Contribution to journalArticle

  75. Published

    Coordination of erythropoiesis by the transcription factor c-Myb

    Alexandros Vegiopoulos, Paloma Garcia & Jon Frampton, 15 Jun 2006, In : Blood. 107, 12, p. 4703-10 8 p.

    Research output: Contribution to journalArticle

  76. Published
  77. Published
  78. Published
  79. Published
  80. 2005
  81. Published

    Generation of a conditional allele of the B-myb gene

    Paloma Garcia, Oscar Berlanga & Jon Frampton, 1 Dec 2005, In : Genesis. 43, p. 189-95 7 p.

    Research output: Contribution to journalArticle

  82. Published
  83. Published
  84. Published

    Selective impairment of platelet activation to collagen in the absence of GATA1

    Sascha Hughan, Yotis Senis, Jon Frampton & Steve Watson, 1 Jun 2005, In : Blood. 105, p. 4369-76 8 p.

    Research output: Contribution to journalArticle

  85. Published

    Expression and functional role for the GPIIb/GPIIIa integrin on bone marrow mast cells

    Oscar Berlanga & Jon Frampton, 1 Jan 2005, In : Exp. Hematol. 33, p. 403-12 10 p.

    Research output: Contribution to journalArticle

  86. 2004
  87. Published
  88. Published
  89. Published
  90. Published

    Myb Transcription Factors: Their Role in Growth, Differentiation and Disease

    Jon Frampton, 1 Jan 2004, Kluwer Academic Publishers.

    Research output: Book/ReportBook

  91. Published
  92. Published

    c-Myb and CREB function in adult neurogenesis

    Jon Frampton & Jon Frampton, 1 Jan 2004, Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  93. 2003
  94. Published

    Functional delivery of large genomic DNA to human cells with a peptide-lipid vector

    Jon Frampton, 1 Oct 2003, In : Journal of Gene Medicine. 5, p. 883-892 10 p.

    Research output: Contribution to journalArticle

  95. Published
  96. Published
  97. Published

    Murine GPVI stimulates weak integrin activation in PLC gamma 2-/- platelets: involvement of PLC gamma 1 and PI3-kinase

    Jon Frampton & Steve Watson, 1 Aug 2003, In : Blood. 102, 4, p. 1367-1373 7 p.

    Research output: Contribution to journalArticle

  98. Published
  99. Published
  100. Published
  101. Published
  102. Published

    Manipulation of gene expression in megakaryocytes

    George Murphy, Jon Frampton, 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  103. Published

    Transcriptional regulation by c-Myb could be a major factor distinguishing the erythroid and megakaryocytic lineages

    Alexandros Vegiopoulos, Jon Frampton & Jon Frampton, 1 Jan 2003, In Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  104. Published

    Using retroviruses to express genes in primary megakaryocyte lineage cells

    George Murphy, Jon Frampton, 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  105. Published

    c-Myb is a key regulator of hematopoietic progenitor expansion and commitment

    Jon Frampton & Jon Frampton, 1 Jan 2003, In Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  106. 2002
  107. Published
  108. Published

    Direct regulation of the bcl-2 gene by Fli-1 is involved in the survival of Fli-1-transformed erythroblasts

    Jon Frampton, 15 Feb 2002, In : The EMBO journal. 21, 4, p. 694-703 10 p.

    Research output: Contribution to journalArticle

  109. Published
  110. 2001
  111. Published
  112. Published
  113. Published
  114. Published

    Myb oncogene

    Jon Frampton, 1 Jan 2001, Encyclopedia of Genetics.

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  115. 2000
  116. Published

    The homeodomain protein PRH influences the differentiation of haematopoietic cells

    Padma-Sheela Jayaraman, Jon Frampton, Dec 2000, In : Leukaemia Research. 24, 12, p. 1023-31 9 p.

    Research output: Contribution to journalArticle