Jon Frampton
Publications
- Book › Research
- Published
Myb Transcription Factors: Their Role in Growth, Differentiation and Disease
Jon Frampton, 1 Jan 2004, Kluwer Academic Publishers.Research output: Book/Report › Book
- Chapter › Research
- Published
Bioluminescence tomography improves quantitative accuracy for pre-clinical imaging
Hector Basevi, Hamid Dehghani, Iain Styles & Jon Frampton, 25 Jun 2013, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
Manipulation of gene expression in megakaryocytes
George Murphy, Jon Frampton, 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
Transcriptional regulation by c-Myb could be a major factor distinguishing the erythroid and megakaryocytic lineages
Alexandros Vegiopoulos, Jon Frampton & Jon Frampton, 1 Jan 2003, In Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
Using retroviruses to express genes in primary megakaryocyte lineage cells
George Murphy, Jon Frampton, 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
c-Myb and CREB function in adult neurogenesis
Jon Frampton & Jon Frampton, 1 Jan 2004, Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
c-Myb is a key regulator of hematopoietic progenitor expansion and commitment
Jon Frampton & Jon Frampton, 1 Jan 2003, In Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Entry for encyclopedia/dictionary › Research
- Published
Myb oncogene
Jon Frampton, 1 Jan 2001, Encyclopedia of Genetics.Research output: Chapter in Book/Report/Conference proceeding › Entry for encyclopedia/dictionary
- Paper › Research › Not peer-reviewed
- Published
- Poster › Research › Not peer-reviewed
- Published
Mesenchymal stem cells inhibit recruitment of flowing neutrophils and lymphocytes by endothelial cells: roles of interleukin-6 and transforming growth factor-{beta}
Christopher Buckley, Nguyet -Thin Luu, Philip Newsome, Jon Frampton & Gerard Nash, Oct 2011.Research output: Contribution to conference (unpublished) › Poster
- Abstract › Research › Not peer-reviewed
- Published
Platelet Endothelial Cell Adhesion Molecule (PECAM)-1 modulates SDF-1alpha/CXCR4 responses of hematopoietic stem cells
Ewan Ross, Sian Lax, Tiezheng Hou, Sylvie Freeman, Stuart Egginton, Tarvinder Dhanjal, Mike Salmon, Steve Watson, Gerard Nash, Jon Frampton & Christopher Buckley, 1 Jan 2006.Research output: Contribution to conference (unpublished) › Abstract
- Published
Platelet endothelial cell adhesion molecule (PECAM)-1 modulates SDF-1a/CXCR4 responses of hematopoietic stem cells
Ewan Ross, Sylvie Freeman, Tarvinder Dhanjal, Sian Lax, Zubair Ahmed, Tiezheng Hou, Stuart Egginton, Gerard Nash, Steve Watson, Jon Frampton & Christopher Buckley, 1 Jan 2009, p. 450. 1 p.Research output: Contribution to conference (unpublished) › Abstract
- Article › Research › Not peer-reviewed
- Published
A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein
Yotis Senis, Michael Tomlinson, Stephanie Dumon, Victoria Heath, Jennifer Spalton, Roy Bicknell, Jon Frampton, Ashley Martin, Mike Wakelam & Steve Watson, 27 Dec 2006, In: Molecular and Cellular Proteomics. 6, p. 548-564 17 p.Research output: Contribution to journal › Article
- Published
A dual role for integrin-linked kinase in platelets: regulating integrin function and -granule secretion
Jon Frampton, 1 Dec 2008, In: Blood. 112, 12, p. 4523-4531 9 p.Research output: Contribution to journal › Article
- Published
Characterization of the c-Myb-responsive Region and Regulation of the Human Type I Collagen alpha 2 Chain Gene by c-Myb
Jon Frampton, 10 Jan 2003, In: Journal of Biological Chemistry. 278, 3, p. 1533-1541 9 p.Research output: Contribution to journal › Article
- Published
Comparative gene analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster
Jon Frampton, 1 Feb 2001, In: Human Molecular Genetics. 10, p. 371-382 12 p.Research output: Contribution to journal › Article
- Published
Coordination of erythropoiesis by the transcription factor c-Myb
Alexandros Vegiopoulos, Paloma Garcia & Jon Frampton, 15 Jun 2006, In: Blood. 107, 12, p. 4703-10 8 p.Research output: Contribution to journal › Article
- Published
Critical roles for c-Myb in lymphoid priming and early B-cell development
Jon Frampton, 1 Apr 2010, In: Blood. 115, 14, p. 2796-2805 10 p.Research output: Contribution to journal › Article
- Published
Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6
Stephanie Dumon, Victoria Heath, Michael Tomlinson & Jon Frampton, 1 May 2006, In: Experimental Hematology. 34, 5, p. 654-63 10 p.Research output: Contribution to journal › Article
- Published
Direct regulation of the bcl-2 gene by Fli-1 is involved in the survival of Fli-1-transformed erythroblasts
Jon Frampton, 15 Feb 2002, In: The EMBO journal. 21, 4, p. 694-703 10 p.Research output: Contribution to journal › Article
- Published
Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code
Jon Frampton, 1 Dec 2008, In: Blood. 112, 12, p. 4512-4522 11 p.Research output: Contribution to journal › Article
- Published
- Published
Evidence That Integrin alpha IIb beta 3-dependent Interaction of Mast Cells with Fibrinogen Exacerbates Chronic Inflammation
Jon Frampton, 1 Nov 2009, In: Journal of Biological Chemistry. 284, 45, p. 31463-31472 10 p.Research output: Contribution to journal › Article
- Published
Expression and functional role for the GPIIb/GPIIIa integrin on bone marrow mast cells
Oscar Berlanga & Jon Frampton, 1 Jan 2005, In: Exp. Hematol. 33, p. 403-12 10 p.Research output: Contribution to journal › Article
- Published
Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors
Jon Frampton, 1 Jun 2009, In: Blood. 113, 23, p. 5783-5792 10 p.Research output: Contribution to journal › Article
- Published
Functional delivery of large genomic DNA to human cells with a peptide-lipid vector
Jon Frampton, 1 Oct 2003, In: Journal of Gene Medicine. 5, p. 883-892 10 p.Research output: Contribution to journal › Article
- Published
Generation of a conditional allele of the B-myb gene
Paloma Garcia, Oscar Berlanga & Jon Frampton, 1 Dec 2005, In: Genesis. 43, p. 189-95 7 p.Research output: Contribution to journal › Article
- Published
- Published
Hematopoietic lineage commitment: miRNAs add specificity to a widely expressed transcription factor
Paloma Garcia & Jon Frampton, 1 Jun 2008, In: Developmental Cell. 14, 6, p. 815-6 2 p.Research output: Contribution to journal › Article
- Published
Heterologous expression of the transcriptional repressor escargot inhibits megakaryocytic endomitosis
Jon Frampton, 9 Nov 2001, In: Journal of Biological Chemistry. 276, p. 43413-43418 6 p.Research output: Contribution to journal › Article
- Published
Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility
Jon Frampton, 15 Apr 2004, In: Genes and Immunity. 5, p. 274-82 9 p.Research output: Contribution to journal › Article
- Published
Integrin a2b1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCg2
Steve Watson & Jon Frampton, 3 Mar 2003, In: Journal of Cell Biology. 160, 5, p. 769-780 12 p.Research output: Contribution to journal › Article
- Published
- Published
Murine GPVI stimulates weak integrin activation in PLC gamma 2-/- platelets: involvement of PLC gamma 1 and PI3-kinase
Jon Frampton & Steve Watson, 1 Aug 2003, In: Blood. 102, 4, p. 1367-1373 7 p.Research output: Contribution to journal › Article
- Published
Phospholipase Cg2-independent activation of integrins by GPVI in murine platelets: involvement of phospholipase Cg1 and PI3-kinase. (In Press)
Jon Frampton, 1 Jan 2002, In: Blood.Research output: Contribution to journal › Article
- Published
Platelet Adhesion Via Glycoprotein IIb Integrin Is Critical for Atheroprogression and Focal Cerebral Ischemia. An In Vivo Study in Mice Lacking Glycoprotein IIb
Jon Frampton, 23 Aug 2005, In: Circulation. 112, p. 1180-8 9 p.Research output: Contribution to journal › Article
- Published
Platelets contribute to postnatal occlusion of the ductus arteriosus
Jon Frampton, 1 Jan 2010, In: Nature Medicine. 16, 1, p. 75-U111Research output: Contribution to journal › Article
- Published
Platelets secrete stromal cell-derived factor 1 and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo
& 1 others, , 17 Apr 2006, In: The Journal of Experimental Medicine. 203, 5, p. 1221-33 13 p.Research output: Contribution to journal › Article
- Published
Professor Alan M Gewirtz (1949-2010) OBITUARY
Jon Frampton, 1 May 2011, In: Oncogene. 30, 19, p. 2187-2187 1 p.Research output: Contribution to journal › Article
- Published
- Published
Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development
Jon Frampton, 1 Aug 2006, In: Blood. 108, 3, p. 896-903 8 p.Research output: Contribution to journal › Article
- Published
RCAS/SCL-TVA Animal Model Allows Targeted Delivery of Polyoma Middle T Oncogene to Vascular Endothelial Progenitors In vivo and Results in Hemangioma Development
Jon Frampton, 15 Jun 2008, In: Clinical Cancer Research. 14, 12, p. 3948-3955 8 p.Research output: Contribution to journal › Article
- Published
Regulation of erythropoiesis by the neuronal transmembrane protein Lrfn2
Jon Frampton, 1 Jan 2007, In: Experimental Hematology. 35, 5, p. 724-734 11 p.Research output: Contribution to journal › Article
- Published
Selective impairment of platelet activation to collagen in the absence of GATA1
Sascha Hughan, Yotis Senis, Jon Frampton & Steve Watson, 1 Jun 2005, In: Blood. 105, p. 4369-76 8 p.Research output: Contribution to journal › Article
- Published
Targeting an E2F site in the mouse genome prevents promoter silencing in quiescent and post-mitotic cells
Fiona Tavner, Jon Frampton, 30 Oct 2006, In: Oncogene. 26, 19, p. 2727-35 9 p.Research output: Contribution to journal › Article
- Published
The Evi-1 proto-oncoprotein blocks endomitosis in megakaryocytes by inhibiting sustained cyclin-dependent kinase 2 catalytic activity
Jon Frampton, 1 Sep 2005, In: British Journal of Haematology. 130, p. 902-11 10 p.Research output: Contribution to journal › Article
- Published
The Fc receptor gamma-chain is necessary and sufficient to initiate signalling through glycoprotein VI
Oscar Berlanga, Jon Frampton, 1 Jun 2002, In: European Journal of Biochemistry. 269, 12, p. 2951-2960 10 p.Research output: Contribution to journal › Article
- Published
The glycoprotein IIb molecule is expressed on early murine hematopoietic progenitors and regulates their numbers in sites of hematopoiesis
Jon Frampton, 1 Jul 2003, In: Immunity. 19, p. 33-45 13 p.Research output: Contribution to journal › Article
- Published
The heptapeptide LSARLAF mediates platelet activation through phospholipase Cy 2 independently of glycoprotein 11b-111a
Andrew Pearce, Steve Watson & Jon Frampton, 15 Feb 2004, In: Biochemical Journal. 378, 1, p. 193-199 7 p.Research output: Contribution to journal › Article
- Published
The scl+19 cell enhancer is not required for haematopoiesis: identification of a second bifunctional hematopoietic/endothelial enhancer regulated by Fil-1 and Elf-1
George Murphy, Jon Frampton, 1 Jan 2004, In: Molecular and Cellular Biology. 24, p. 1870-1883 14 p.Research output: Contribution to journal › Article