Jon Frampton

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Publications

  1. Book › Research
  2. Published

    Myb Transcription Factors: Their Role in Growth, Differentiation and Disease

    Jon Frampton, 1 Jan 2004, Kluwer Academic Publishers.

    Research output: Book/Report › Book

  3. Chapter › Research
  4. Published

    Bioluminescence tomography improves quantitative accuracy for pre-clinical imaging

    Hector Basevi, Hamid Dehghani, Iain Styles & Jon Frampton, 25 Jun 2013, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  5. Published

    Manipulation of gene expression in megakaryocytes

    George Murphy, Jon Frampton, 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  6. Published

    Transcriptional regulation by c-Myb could be a major factor distinguishing the erythroid and megakaryocytic lineages

    Alexandros Vegiopoulos, Jon Frampton & Jon Frampton, 1 Jan 2003, In Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  7. Published

    Using retroviruses to express genes in primary megakaryocyte lineage cells

    George Murphy, Jon Frampton, 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  8. Published

    c-Myb and CREB function in adult neurogenesis

    Jon Frampton & Jon Frampton, 1 Jan 2004, Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  9. Published

    c-Myb is a key regulator of hematopoietic progenitor expansion and commitment

    Jon Frampton & Jon Frampton, 1 Jan 2003, In Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  10. Entry for encyclopedia/dictionary › Research
  11. Published

    Myb oncogene

    Jon Frampton, 1 Jan 2001, Encyclopedia of Genetics.

    Research output: Chapter in Book/Report/Conference proceeding › Entry for encyclopedia/dictionary

  12. Paper › Research › Not peer-reviewed
  13. Published

    Development of a multi-view, multi-spectral bioluminescence tomography small animal imaging system

    Hamid Dehghani, Hector Basevi, Iain Styles, Jon Frampton, 22 May 2011, p. 80881K.

    Research output: Contribution to conference (unpublished) › Paper

  14. Poster › Research › Not peer-reviewed
  15. Published

    Mesenchymal stem cells inhibit recruitment of flowing neutrophils and lymphocytes by endothelial cells: roles of interleukin-6 and transforming growth factor-{beta}

    Christopher Buckley, Nguyet -Thin Luu, Philip Newsome, Jon Frampton & Gerard Nash, Oct 2011.

    Research output: Contribution to conference (unpublished) › Poster

  16. Abstract › Research › Not peer-reviewed
  17. Published

    Platelet Endothelial Cell Adhesion Molecule (PECAM)-1 modulates SDF-1alpha/CXCR4 responses of hematopoietic stem cells

    Ewan Ross, Sian Lax, Tiezheng Hou, Sylvie Freeman, Stuart Egginton, Tarvinder Dhanjal, Mike Salmon, Steve Watson, Gerard Nash, Jon Frampton & Christopher Buckley, 1 Jan 2006.

    Research output: Contribution to conference (unpublished) › Abstract

  18. Published

    Platelet endothelial cell adhesion molecule (PECAM)-1 modulates SDF-1a/CXCR4 responses of hematopoietic stem cells

    Ewan Ross, Sylvie Freeman, Tarvinder Dhanjal, Sian Lax, Zubair Ahmed, Tiezheng Hou, Stuart Egginton, Gerard Nash, Steve Watson, Jon Frampton & Christopher Buckley, 1 Jan 2009, p. 450. 1 p.

    Research output: Contribution to conference (unpublished) › Abstract

  19. Article › Research › Not peer-reviewed
  20. Published

    A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein

    Yotis Senis, Michael Tomlinson, Stephanie Dumon, Victoria Heath, Jennifer Spalton, Roy Bicknell, Jon Frampton, Ashley Martin, Mike Wakelam & Steve Watson, 27 Dec 2006, In: Molecular and Cellular Proteomics. 6, p. 548-564 17 p.

    Research output: Contribution to journal › Article

  21. Published

    A dual role for integrin-linked kinase in platelets: regulating integrin function and  -granule secretion

    Jon Frampton, 1 Dec 2008, In: Blood. 112, 12, p. 4523-4531 9 p.

    Research output: Contribution to journal › Article

  22. Published

    Characterization of the c-Myb-responsive Region and Regulation of the Human Type I Collagen alpha 2 Chain Gene by c-Myb

    Jon Frampton, 10 Jan 2003, In: Journal of Biological Chemistry. 278, 3, p. 1533-1541 9 p.

    Research output: Contribution to journal › Article

  23. Published

    Comparative gene analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster

    Jon Frampton, 1 Feb 2001, In: Human Molecular Genetics. 10, p. 371-382 12 p.

    Research output: Contribution to journal › Article

  24. Published

    Coordination of erythropoiesis by the transcription factor c-Myb

    Alexandros Vegiopoulos, Paloma Garcia & Jon Frampton, 15 Jun 2006, In: Blood. 107, 12, p. 4703-10 8 p.

    Research output: Contribution to journal › Article

  25. Published

    Critical roles for c-Myb in lymphoid priming and early B-cell development

    Jon Frampton, 1 Apr 2010, In: Blood. 115, 14, p. 2796-2805 10 p.

    Research output: Contribution to journal › Article

  26. Published

    Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6

    Stephanie Dumon, Victoria Heath, Michael Tomlinson & Jon Frampton, 1 May 2006, In: Experimental Hematology. 34, 5, p. 654-63 10 p.

    Research output: Contribution to journal › Article

  27. Published

    Direct regulation of the bcl-2 gene by Fli-1 is involved in the survival of Fli-1-transformed erythroblasts

    Jon Frampton, 15 Feb 2002, In: The EMBO journal. 21, 4, p. 694-703 10 p.

    Research output: Contribution to journal › Article

  28. Published

    Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

    Jon Frampton, 1 Dec 2008, In: Blood. 112, 12, p. 4512-4522 11 p.

    Research output: Contribution to journal › Article

  29. Published

    Evaluation of the role of platelet integrins in fibronectindependent spreading and adhesion

    Steve Watson, Owen McCarty, Laura Machesky & Jon Frampton, 1 Oct 2004, In: Journal of Thrombosis and Haemostasis. 2, 10, p. 1823-1833 11 p.

    Research output: Contribution to journal › Article

  30. Published

    Evidence That Integrin alpha IIb beta 3-dependent Interaction of Mast Cells with Fibrinogen Exacerbates Chronic Inflammation

    Jon Frampton, 1 Nov 2009, In: Journal of Biological Chemistry. 284, 45, p. 31463-31472 10 p.

    Research output: Contribution to journal › Article

  31. Published

    Expression and functional role for the GPIIb/GPIIIa integrin on bone marrow mast cells

    Oscar Berlanga & Jon Frampton, 1 Jan 2005, In: Exp. Hematol. 33, p. 403-12 10 p.

    Research output: Contribution to journal › Article

  32. Published

    Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

    Jon Frampton, 1 Jun 2009, In: Blood. 113, 23, p. 5783-5792 10 p.

    Research output: Contribution to journal › Article

  33. Published

    Functional delivery of large genomic DNA to human cells with a peptide-lipid vector

    Jon Frampton, 1 Oct 2003, In: Journal of Gene Medicine. 5, p. 883-892 10 p.

    Research output: Contribution to journal › Article

  34. Published

    Generation of a conditional allele of the B-myb gene

    Paloma Garcia, Oscar Berlanga & Jon Frampton, 1 Dec 2005, In: Genesis. 43, p. 189-95 7 p.

    Research output: Contribution to journal › Article

  35. Published

    Glycoprotein VI oligomerization in cell lines and platelets

    Oscar Berlanga, Jon Frampton, Michael Tomlinson & Steve Watson, 1 May 2007, In: Journal of Thrombosis and Haemostasis. 5, 5, p. 1026-33 8 p.

    Research output: Contribution to journal › Article

  36. Published

    Hematopoietic lineage commitment: miRNAs add specificity to a widely expressed transcription factor

    Paloma Garcia & Jon Frampton, 1 Jun 2008, In: Developmental Cell. 14, 6, p. 815-6 2 p.

    Research output: Contribution to journal › Article

  37. Published

    Heterologous expression of the transcriptional repressor escargot inhibits megakaryocytic endomitosis

    Jon Frampton, 9 Nov 2001, In: Journal of Biological Chemistry. 276, p. 43413-43418 6 p.

    Research output: Contribution to journal › Article

  38. Published

    Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility

    Jon Frampton, 15 Apr 2004, In: Genes and Immunity. 5, p. 274-82 9 p.

    Research output: Contribution to journal › Article

  39. Published

    Integrin a2b1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCg2

    Steve Watson & Jon Frampton, 3 Mar 2003, In: Journal of Cell Biology. 160, 5, p. 769-780 12 p.

    Research output: Contribution to journal › Article

  40. Published

    Manipulation of mouse hematopoietic progenitors by specific retroviral infection

    George Murphy, Alexandros Vegiopoulos, Steve Watson & Jon Frampton, 1 Oct 2003, In: Journal of Biological Chemistry. 278, 44, p. 43556-43563 8 p.

    Research output: Contribution to journal › Article

  41. Published

    Murine GPVI stimulates weak integrin activation in PLC gamma 2-/- platelets: involvement of PLC gamma 1 and PI3-kinase

    Jon Frampton & Steve Watson, 1 Aug 2003, In: Blood. 102, 4, p. 1367-1373 7 p.

    Research output: Contribution to journal › Article

  42. Published

    Phospholipase Cg2-independent activation of integrins by GPVI in murine platelets: involvement of phospholipase Cg1 and PI3-kinase. (In Press)

    Jon Frampton, 1 Jan 2002, In: Blood.

    Research output: Contribution to journal › Article

  43. Published

    Platelet Adhesion Via Glycoprotein IIb Integrin Is Critical for Atheroprogression and Focal Cerebral Ischemia. An In Vivo Study in Mice Lacking Glycoprotein IIb

    Jon Frampton, 23 Aug 2005, In: Circulation. 112, p. 1180-8 9 p.

    Research output: Contribution to journal › Article

  44. Published

    Platelets contribute to postnatal occlusion of the ductus arteriosus

    Jon Frampton, 1 Jan 2010, In: Nature Medicine. 16, 1, p. 75-U111

    Research output: Contribution to journal › Article

  45. Published

    Platelets secrete stromal cell-derived factor 1  and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo

    & 1 others, Jon Frampton, 17 Apr 2006, In: The Journal of Experimental Medicine. 203, 5, p. 1221-33 13 p.

    Research output: Contribution to journal › Article

  46. Published

    Professor Alan M Gewirtz (1949-2010) OBITUARY

    Jon Frampton, 1 May 2011, In: Oncogene. 30, 19, p. 2187-2187 1 p.

    Research output: Contribution to journal › Article

  47. Published

    Progression through key stages of the haemopoiesis is dependent on distinct threshold levels of c-Myb

    Alexandros Vegiopoulos, Ben Harman, Eric Jenkinson, Graham Anderson & Jon Frampton, 1 Sep 2003, In: The EMBO journal. 22, p. 4478-4488 11 p.

    Research output: Contribution to journal › Article

  48. Published

    Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development

    Jon Frampton, 1 Aug 2006, In: Blood. 108, 3, p. 896-903 8 p.

    Research output: Contribution to journal › Article

  49. Published

    RCAS/SCL-TVA Animal Model Allows Targeted Delivery of Polyoma Middle T Oncogene to Vascular Endothelial Progenitors In vivo and Results in Hemangioma Development

    Jon Frampton, 15 Jun 2008, In: Clinical Cancer Research. 14, 12, p. 3948-3955 8 p.

    Research output: Contribution to journal › Article

  50. Published

    Regulation of erythropoiesis by the neuronal transmembrane protein Lrfn2

    Jon Frampton, 1 Jan 2007, In: Experimental Hematology. 35, 5, p. 724-734 11 p.

    Research output: Contribution to journal › Article

  51. Published

    Selective impairment of platelet activation to collagen in the absence of GATA1

    Sascha Hughan, Yotis Senis, Jon Frampton & Steve Watson, 1 Jun 2005, In: Blood. 105, p. 4369-76 8 p.

    Research output: Contribution to journal › Article

  52. Published

    Targeting an E2F site in the mouse genome prevents promoter silencing in quiescent and post-mitotic cells

    Fiona Tavner, Jon Frampton, 30 Oct 2006, In: Oncogene. 26, 19, p. 2727-35 9 p.

    Research output: Contribution to journal › Article

  53. Published

    The Evi-1 proto-oncoprotein blocks endomitosis in megakaryocytes by inhibiting sustained cyclin-dependent kinase 2 catalytic activity

    Jon Frampton, 1 Sep 2005, In: British Journal of Haematology. 130, p. 902-11 10 p.

    Research output: Contribution to journal › Article

  54. Published

    The Fc receptor gamma-chain is necessary and sufficient to initiate signalling through glycoprotein VI

    Oscar Berlanga, Jon Frampton, 1 Jun 2002, In: European Journal of Biochemistry. 269, 12, p. 2951-2960 10 p.

    Research output: Contribution to journal › Article

  55. Published

    The glycoprotein IIb molecule is expressed on early murine hematopoietic progenitors and regulates their numbers in sites of hematopoiesis

    Jon Frampton, 1 Jul 2003, In: Immunity. 19, p. 33-45 13 p.

    Research output: Contribution to journal › Article

  56. Published

    The heptapeptide LSARLAF mediates platelet activation through phospholipase Cy 2 independently of glycoprotein 11b-111a

    Andrew Pearce, Steve Watson & Jon Frampton, 15 Feb 2004, In: Biochemical Journal. 378, 1, p. 193-199 7 p.

    Research output: Contribution to journal › Article

  57. Published

    The scl+19 cell enhancer is not required for haematopoiesis: identification of a second bifunctional hematopoietic/endothelial enhancer regulated by Fil-1 and Elf-1

    George Murphy, Jon Frampton, 1 Jan 2004, In: Molecular and Cellular Biology. 24, p. 1870-1883 14 p.

    Research output: Contribution to journal › Article

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