Jon Frampton

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Publications

  1. Published

    Mechanisms of adhesion and subsequent actions of a haematopoietic stem cell line, HPC-7, in the injured murine intestinal microcirculation in vivo

    Dean Kavanagh, Adrian Yemm, Yan Zhao, Jon Frampton & Neena Kalia, 2013, In: PLoS ONE. 8, 3, p. e59150

    Research output: Contribution to journal › Article › peer-review

  2. Published

    Manipulation of mouse hematopoietic progenitors by specific retroviral infection

    George Murphy, Alexandros Vegiopoulos, Steve Watson & Jon Frampton, 1 Oct 2003, In: Journal of Biological Chemistry. 278, 44, p. 43556-43563 8 p.

    Research output: Contribution to journal › Article

  3. Published

    Manipulation of gene expression in megakaryocytes

    George Murphy, Jon Frampton, 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  4. Published

    MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia

    Stephanie Dumon, Sylvie Freeman, Ban Dawood, Lozan Sheriff, Maelle Lorvellec, Jon Frampton & Paloma Garcia, 2012, In: Leukemia. 27, 3, p. 661-670 10 p.

    Research output: Contribution to journal › Article › peer-review

  5. Published

    Itga2b regulation at the onset of definitive hematopoiesis and commitment to differentiation

    Stephanie Dumon, Emilie Dasse, Walter Del Pozzo, Bryan Turner, Laura O'Neill & Jon Frampton, 2012, In: PLoS ONE. 7, 8, p. e43300

    Research output: Contribution to journal › Article › peer-review

  6. Published

    Integrin a2b1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCg2

    Steve Watson & Jon Frampton, 3 Mar 2003, In: Journal of Cell Biology. 160, 5, p. 769-780 12 p.

    Research output: Contribution to journal › Article

  7. Published

    Inducible disruption of the c-myb gene allows allogeneic bone marrow transplantation without irradiation

    Jon Frampton, 1 Jun 2018, In: Journal of Immunological Methods. 457, p. 66-72

    Research output: Contribution to journal › Article › peer-review

  8. Published

    Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility

    Jon Frampton, 15 Apr 2004, In: Genes and Immunity. 5, p. 274-82 9 p.

    Research output: Contribution to journal › Article

  9. Published

    Human mesenchymal stem cells are recruited to injured liver in a β1-integrin and CD44 dependent manner

    Victoria Day, Abhilok Garg, Nick Davies, David Bartlett, Heather Beard, Dean Kavanagh, Neena Kalia, Jon Frampton, Trish Lalor & Philip Newsome, 1 Sep 2012, In: Hepatology. 56, 3, p. 1063-1073 11 p.

    Research output: Contribution to journal › Article › peer-review

  10. Published

    High WBP5 expression correlates with elevation of HOX genes levels and is associated with inferior survival in patients with acute myeloid leukaemia

    Paloma Garcia, Jon Frampton, 26 Feb 2020, In: Scientific Reports. 10, 1, 3505.

    Research output: Contribution to journal › Article › peer-review

  11. Published

    Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

    Jon Frampton, 1 Jun 2011, In: The Journal of Experimental Medicine. 208, 6, p. 1305-1315 11 p.

    Research output: Contribution to journal › Article › peer-review

  12. Published

    Heterologous expression of the transcriptional repressor escargot inhibits megakaryocytic endomitosis

    Jon Frampton, 9 Nov 2001, In: Journal of Biological Chemistry. 276, p. 43413-43418 6 p.

    Research output: Contribution to journal › Article

  13. Published

    Hematopoietic lineage commitment: miRNAs add specificity to a widely expressed transcription factor

    Paloma Garcia & Jon Frampton, 1 Jun 2008, In: Developmental Cell. 14, 6, p. 815-6 2 p.

    Research output: Contribution to journal › Article

  14. Published

    Harnessing genomics to improve outcomes for women with cancer in India: key priorities for research

    Sudha Sundar, Jean-Baptiste Cazier & Jon Frampton, 15 Feb 2018, In: The Lancet Oncology. 19, 2, p. e102–e112

    Research output: Contribution to journal › Article › peer-review

  15. Published

    Haematopoietic stem cell recruitment to injured murine liver sinusoids depends on alpha(4)beta(1) integrin/VCAM-1 interactions

    Dean Kavanagh, Heather Beard, Trish Lalor, Jon Frampton, David Adams & Neena Kalia, 1 Jan 2009, In: Gut. 59, 1, p. 79-87 9 p.

    Research output: Contribution to journal › Article › peer-review

  16. Published

    Glycoprotein VI oligomerization in cell lines and platelets

    Oscar Berlanga, Jon Frampton, Michael Tomlinson & Steve Watson, 1 May 2007, In: Journal of Thrombosis and Haemostasis. 5, 5, p. 1026-33 8 p.

    Research output: Contribution to journal › Article

  17. Published

    Generation of knockout rabbits using transcription activator-like effector nucleases

    Philip Newsome, Jon Frampton, 5 Feb 2014, In: Cell Regeneration . 3, 3.

    Research output: Contribution to journal › Article › peer-review

  18. Published

    Generation of a conditional allele of the B-myb gene

    Paloma Garcia, Oscar Berlanga & Jon Frampton, 1 Dec 2005, In: Genesis. 43, p. 189-95 7 p.

    Research output: Contribution to journal › Article

  19. Published

    Functional delivery of large genomic DNA to human cells with a peptide-lipid vector

    Jon Frampton, 1 Oct 2003, In: Journal of Gene Medicine. 5, p. 883-892 10 p.

    Research output: Contribution to journal › Article

  20. Published

    Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1

    Philip Newsome, Jon Frampton & 4 others, , 17 Mar 2017, In: Journal of Biological Chemistry. 292, 11, p. 4755-4763 9 p.

    Research output: Contribution to journal › Article › peer-review

  21. Published

    Fine-tuning Mybl2 is required for proper mesenchymal-to-epithelial transition during somatic reprogramming

    Carl Ward, Giacomo Volpe, Pierre Cauchy, Anetta Ptasinska, Jon Frampton & Paloma Garcia, 7 Aug 2018, In: Cell Reports. 24, 6, p. 1496-1511.e8 24 p.

    Research output: Contribution to journal › Article › peer-review

  22. Published

    Fibrin activates GPVI in human and mouse platelets

    Craig Hughes, Jon Frampton & Steve Watson, 24 Sep 2015, In: Blood. 126, 13, p. 1601-1608 8 p.

    Research output: Contribution to journal › Article › peer-review

  23. Published

    Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

    Jon Frampton, 1 Jun 2009, In: Blood. 113, 23, p. 5783-5792 10 p.

    Research output: Contribution to journal › Article

  24. Published

    Expression and functional role for the GPIIb/GPIIIa integrin on bone marrow mast cells

    Oscar Berlanga & Jon Frampton, 1 Jan 2005, In: Exp. Hematol. 33, p. 403-12 10 p.

    Research output: Contribution to journal › Article

  25. Published

    Evidence That Integrin alpha IIb beta 3-dependent Interaction of Mast Cells with Fibrinogen Exacerbates Chronic Inflammation

    Jon Frampton, 1 Nov 2009, In: Journal of Biological Chemistry. 284, 45, p. 31463-31472 10 p.

    Research output: Contribution to journal › Article

  26. Published

    Evaluation of the role of platelet integrins in fibronectindependent spreading and adhesion

    Steve Watson, Owen McCarty, Laura Machesky & Jon Frampton, 1 Oct 2004, In: Journal of Thrombosis and Haemostasis. 2, 10, p. 1823-1833 11 p.

    Research output: Contribution to journal › Article

  27. Published

    Enhancing the adhesion of haematopoietic precursor cell integrins with hydrogen peroxide increases recruitment within murine gut

    Dean Kavanagh, Adrian Yemm, Jon Frampton & Neena Kalia, 2013, In: Cell transplantation. 22, 8, p. 1485-1499 15 p.

    Research output: Contribution to journal › Article › peer-review

  28. Published

    Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

    Jon Frampton, 1 Dec 2008, In: Blood. 112, 12, p. 4512-4522 11 p.

    Research output: Contribution to journal › Article

  29. Published

    Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level

    Jon Frampton, 2013, In: Nature Communications. 4, p. 2924

    Research output: Contribution to journal › Article › peer-review

  30. Published

    EMMPRIN (CD147/basigin) mediates platelet-monocyte interactions in vivo and augments monocyte recruitment to the vascular wall

    Jon Frampton, 1 May 2011, In: Journal of Thrombosis and Haemostasis. 9, 5, p. 1007-1019 13 p.

    Research output: Contribution to journal › Article › peer-review

  31. Published

    Distinct regulation of c-myb gene expression by HoxA9, Meis1 and Pbx proteins in normal hematopoietic progenitors and transformed myeloid cells

    Emilie Dasse, Giacomo Volpe, Doug Walton, Neil Wilson, Walter Del Pozzo, Laura O'Neill, Jon Frampton & Stephanie Dumon, Jun 2012, In: Blood Cancer Journal. 2, 6, p. e76

    Research output: Contribution to journal › Article › peer-review

  32. Published

    Direct regulation of the bcl-2 gene by Fli-1 is involved in the survival of Fli-1-transformed erythroblasts

    Jon Frampton, 15 Feb 2002, In: The EMBO journal. 21, 4, p. 694-703 10 p.

    Research output: Contribution to journal › Article

  33. Published

    Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6

    Stephanie Dumon, Victoria Heath, Michael Tomlinson & Jon Frampton, 1 May 2006, In: Experimental Hematology. 34, 5, p. 654-63 10 p.

    Research output: Contribution to journal › Article

  34. Published

    Development of a multi-view, multi-spectral bioluminescence tomography small animal imaging system

    Hamid Dehghani, Hector Basevi, Iain Styles, Jon Frampton, 22 May 2011, p. 80881K.

    Research output: Contribution to conference (unpublished) › Paper

  35. Published

    Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes

    Paloma Garcia, Jon Frampton, Feb 2015, In: Stem Cells. 33, 2, p. 479-490 12 p.

    Research output: Contribution to journal › Article › peer-review

  36. Published

    Crosstalk between mesenchymal stem cells and endothelial cells leads to down-regulation of cytokine-induced leukocyte recruitment

    Nguyet -Thin Luu, Helen McGettrick, Christopher Buckley, Philip Newsome, Ed Rainger, Jon Frampton & Gerard Nash, Dec 2013, In: Stem Cells. 31, 12, p. 2690-2702

    Research output: Contribution to journal › Article › peer-review

  37. Published

    Critical roles for c-Myb in lymphoid priming and early B-cell development

    Jon Frampton, 1 Apr 2010, In: Blood. 115, 14, p. 2796-2805 10 p.

    Research output: Contribution to journal › Article

  38. Published

    Coordination of erythropoiesis by the transcription factor c-Myb

    Alexandros Vegiopoulos, Paloma Garcia & Jon Frampton, 15 Jun 2006, In: Blood. 107, 12, p. 4703-10 8 p.

    Research output: Contribution to journal › Article

  39. Published

    Comparative gene analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster

    Jon Frampton, 1 Feb 2001, In: Human Molecular Genetics. 10, p. 371-382 12 p.

    Research output: Contribution to journal › Article

  40. Published

    Characterization of the c-Myb-responsive Region and Regulation of the Human Type I Collagen alpha 2 Chain Gene by c-Myb

    Jon Frampton, 10 Jan 2003, In: Journal of Biological Chemistry. 278, 3, p. 1533-1541 9 p.

    Research output: Contribution to journal › Article

  41. Published

    CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex

    Giacomo Volpe, Jon Frampton, Jul 2019, In: Leukemia. 33, p. 1608-1619 12 p.

    Research output: Contribution to journal › Article › peer-review

  42. Published

    C/EBPα and MYB regulate FLT3 expression in AML

    Giacomo Volpe, Paloma Garcia, Emilie Dasse, Laura O'Neill, Jon Frampton & Stephanie Dumon, 23 Jan 2013, In: Leukemia. 27, 7, p. 1487-1496 10 p.

    Research output: Contribution to journal › Article › peer-review

  43. Published

    Bioluminescence tomography improves quantitative accuracy for pre-clinical imaging

    Hector Basevi, Hamid Dehghani, Iain Styles & Jon Frampton, 25 Jun 2013, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  44. Published

    B-Myb is Critical for Proper Duplication During an Unperturbed s Phase in Mouse Embryonic Stem Cells.

    Maelle Lorvellec, Stephanie Dumon, Jon Frampton & Paloma Garcia, 16 Aug 2010, In: Stem Cells. 28, 10, p. 1751-1759 9 p.

    Research output: Contribution to journal › Article › peer-review

  45. Published

    Author Correction: High WBP5 expression correlates with elevation of HOX genes levels and is associated with inferior survival in patients with acute myeloid leukaemia (Scientific Reports, (2020), 10, 1, (3505), 10.1038/s41598-020-60480-x)

    Pierre Cauchy, Paloma Garcia, Jon Frampton & Giacomo Volpe, 1 Dec 2020, In: Scientific Reports. 10, 1, 13109.

    Research output: Contribution to journal › Comment/debate › peer-review

  46. Published

    A dual role for integrin-linked kinase in platelets: regulating integrin function and  -granule secretion

    Jon Frampton, 1 Dec 2008, In: Blood. 112, 12, p. 4523-4531 9 p.

    Research output: Contribution to journal › Article

  47. Published

    A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein

    Yotis Senis, Michael Tomlinson, Stephanie Dumon, Victoria Heath, Jennifer Spalton, Roy Bicknell, Jon Frampton, Ashley Martin, Mike Wakelam & Steve Watson, 27 Dec 2006, In: Molecular and Cellular Proteomics. 6, p. 548-564 17 p.

    Research output: Contribution to journal › Article

  48. Published

    A Novel Role for PECAM-1 (CD31) in Regulating Haematopoietic Progenitor Cell Compartmentalization between the Peripheral Blood and Bone Marrow

    Ewan Ross, Sylvie Freeman, Yan Zhao, Tarvinder Dhanjal, Sian Lax, Zubair Ahmed, Neena Kalia, Stuart Egginton, Gerard Nash, Steve Watson, Jon Frampton & Christopher Buckley, 4 Jun 2008, In: PLoS ONE. 3, 6, 10 p., e2338.

    Research output: Contribution to journal › Article › peer-review

  49. Published

    A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

    Jon Frampton, 1 Apr 2012, In: Science. 336, 6077, p. 86-90 5 p.

    Research output: Contribution to journal › Article › peer-review

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