Jon Frampton
Publications
- 2020
- Published
Author Correction: High WBP5 expression correlates with elevation of HOX genes levels and is associated with inferior survival in patients with acute myeloid leukaemia (Scientific Reports, (2020), 10, 1, (3505), 10.1038/s41598-020-60480-x)
Pierre Cauchy, Paloma Garcia, Jon Frampton & Giacomo Volpe, 1 Dec 2020, In: Scientific Reports. 10, 1, 13109.Research output: Contribution to journal › Comment/debate › peer-review
- Published
High WBP5 expression correlates with elevation of HOX genes levels and is associated with inferior survival in patients with acute myeloid leukaemia
Paloma Garcia, Jon Frampton, 26 Feb 2020, In: Scientific Reports. 10, 1, 3505.Research output: Contribution to journal › Article › peer-review
- 2019
- Published
CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex
Giacomo Volpe, Jon Frampton, Jul 2019, In: Leukemia. 33, p. 1608-1619 12 p.Research output: Contribution to journal › Article › peer-review
- 2018
- Published
Fine-tuning Mybl2 is required for proper mesenchymal-to-epithelial transition during somatic reprogramming
Carl Ward, Giacomo Volpe, Pierre Cauchy, Anetta Ptasinska, Jon Frampton & Paloma Garcia, 7 Aug 2018, In: Cell Reports. 24, 6, p. 1496-1511.e8 24 p.Research output: Contribution to journal › Article › peer-review
- Published
Inducible disruption of the c-myb gene allows allogeneic bone marrow transplantation without irradiation
Jon Frampton, 1 Jun 2018, In: Journal of Immunological Methods. 457, p. 66-72Research output: Contribution to journal › Article › peer-review
- Published
Harnessing genomics to improve outcomes for women with cancer in India: key priorities for research
Sudha Sundar, Jean-Baptiste Cazier & Jon Frampton, 15 Feb 2018, In: The Lancet Oncology. 19, 2, p. e102–e112Research output: Contribution to journal › Article › peer-review
- Published
Origin-specific Adhesive Interactions of Mesenchymal Stem Cells with Platelets Influence their Behaviour After Infusion.
Julie Rayes, Stephen Watson, Philip Newsome, Neena Kalia, Jon Frampton, Helen McGettrick & Gerard Nash, Feb 2018, In: Stem cells (Dayton, Ohio).Research output: Contribution to journal › Article › peer-review
- 2017
- Published
Prognostic significance of high GFI1 expression in AML of normal karyotype and its association with a FLT3-ITD signature
Giacomo Volpe, David Grainger, Carl Ward, Pierre Cauchy, Daniel Coleman, Peter Cockerill, Paloma Garcia & Jon Frampton, 11 Sep 2017, In: Scientific Reports. 7, 11148.Research output: Contribution to journal › Article › peer-review
- Published
Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1
Philip Newsome, Jon Frampton & 4 others, , 17 Mar 2017, In: Journal of Biological Chemistry. 292, 11, p. 4755-4763 9 p.Research output: Contribution to journal › Article › peer-review
- Published
Targeting the transcription factor Myb by small-molecule inhibitors
Jon Frampton, 1 Mar 2017, In: Experimental Hematology. 47, p. 31-35Research output: Contribution to journal › Article › peer-review
- 2016
- E-pub ahead of print
Transcriptional regulation of SPROUTY 2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3
Mary Clarke, Giacomo Volpe, Lozan Sheriff, Carl Ward, Wenbin Wei, Stephanie Dumon, Paloma Garcia & Jon Frampton, 8 Nov 2016, In: Leukemia.Research output: Contribution to journal › Article › peer-review
- 2015
- E-pub ahead of print
Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction
Emilie Dasse, Jon Frampton, 2 Dec 2015, In: Blood.Research output: Contribution to journal › Article › peer-review
- Published
Fibrin activates GPVI in human and mouse platelets
Craig Hughes, Jon Frampton & Steve Watson, 24 Sep 2015, In: Blood. 126, 13, p. 1601-1608 8 p.Research output: Contribution to journal › Article › peer-review
- Published
Regulation of the Flt3 gene in haematopoietic stem and early progenitor cells
Giacomo Volpe, Mary Clarke, Paloma Garcia, Alexandros Vegiopoulos, Walter Del Pozzo, Jon Frampton & Stephanie Dumon, 18 Sep 2015, In: PLoS ONE. 10, 9, e0138257.Research output: Contribution to journal › Article › peer-review
- Published
Pretreatment of Mesenchymal Stem Cells Manipulates Their Vasculoprotective Potential While Not Altering Their Homing Within the Injured Gut
Dean Kavanagh, Philip Newsome, Jon Frampton & Neena Kalia, 24 Aug 2015, In: Stem Cells. 33, 9, p. 2785-97 13 p.Research output: Contribution to journal › Article › peer-review
- Published
- Published
Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes
Paloma Garcia, Jon Frampton, Feb 2015, In: Stem Cells. 33, 2, p. 479-490 12 p.Research output: Contribution to journal › Article › peer-review
- Published
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters
Jon Frampton & 1 others, , Jan 2015, In: Cell Research. 25, 1, p. 80-92 13 p.Research output: Contribution to journal › Article › peer-review
- 2014
- Published
Transcriptional pause release is a rate-limiting step for somatic cell reprogramming
Yuan Li & 12 others, , 6 Nov 2014, In: Cell stem cell. 15, 5, p. 574-88 15 p.Research output: Contribution to journal › Article › peer-review
- Published
RAG1/2 knockout pigs with severe combined immunodeficiency
Jon Frampton, 1 Aug 2014, In: Journal of Immunology. 193, 3, p. 1496-503 8 p.Research output: Contribution to journal › Article › peer-review
- Published
Generation of knockout rabbits using transcription activator-like effector nucleases
Philip Newsome, Jon Frampton, 5 Feb 2014, In: Cell Regeneration . 3, 3.Research output: Contribution to journal › Article › peer-review
- 2013
- Published
Crosstalk between mesenchymal stem cells and endothelial cells leads to down-regulation of cytokine-induced leukocyte recruitment
Nguyet -Thin Luu, Helen McGettrick, Christopher Buckley, Philip Newsome, Ed Rainger, Jon Frampton & Gerard Nash, Dec 2013, In: Stem Cells. 31, 12, p. 2690-2702Research output: Contribution to journal › Article › peer-review
- Published
Multi-modal molecular diffuse optical tomography system for small animal imaging
Hector Basevi, Jon Frampton, Iain Styles & Hamid Dehghani, 10 Sep 2013, In: Measurement Science and Technology. 24, 10, 22 p., 105405.Research output: Contribution to journal › Article › peer-review
- Published
Bioluminescence tomography improves quantitative accuracy for pre-clinical imaging
Hector Basevi, Hamid Dehghani, Iain Styles & Jon Frampton, 25 Jun 2013, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
- Published
Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level
Jon Frampton, 2013, In: Nature Communications. 4, p. 2924Research output: Contribution to journal › Article › peer-review
- Published
Enhancing the adhesion of haematopoietic precursor cell integrins with hydrogen peroxide increases recruitment within murine gut
Dean Kavanagh, Adrian Yemm, Jon Frampton & Neena Kalia, 2013, In: Cell transplantation. 22, 8, p. 1485-1499 15 p.Research output: Contribution to journal › Article › peer-review
- Published
Mechanisms of adhesion and subsequent actions of a haematopoietic stem cell line, HPC-7, in the injured murine intestinal microcirculation in vivo
Dean Kavanagh, Adrian Yemm, Yan Zhao, Jon Frampton & Neena Kalia, 2013, In: PLoS ONE. 8, 3, p. e59150Research output: Contribution to journal › Article › peer-review
- 2012
- Published
The TspanC8 subgroup of tetraspanins interacts with a disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression
Elizabeth Haining, Steve Watson, Jon Frampton, Paloma Garcia & Michael Tomlinson, 16 Nov 2012, In: Journal of Biological Chemistry. 287, 47, p. 39753-39765 13 p.Research output: Contribution to journal › Article › peer-review
- Published
Human mesenchymal stem cells are recruited to injured liver in a β1-integrin and CD44 dependent manner
Victoria Day, Abhilok Garg, Nick Davies, David Bartlett, Heather Beard, Dean Kavanagh, Neena Kalia, Jon Frampton, Trish Lalor & Philip Newsome, 1 Sep 2012, In: Hepatology. 56, 3, p. 1063-1073 11 p.Research output: Contribution to journal › Article › peer-review
- Published
Distinct regulation of c-myb gene expression by HoxA9, Meis1 and Pbx proteins in normal hematopoietic progenitors and transformed myeloid cells
Emilie Dasse, Giacomo Volpe, Doug Walton, Neil Wilson, Walter Del Pozzo, Laura O'Neill, Jon Frampton & Stephanie Dumon, Jun 2012, In: Blood Cancer Journal. 2, 6, p. e76Research output: Contribution to journal › Article › peer-review
- Published
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
Jon Frampton, 1 Apr 2012, In: Science. 336, 6077, p. 86-90 5 p.Research output: Contribution to journal › Article › peer-review
- Published
- Published
MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia
Stephanie Dumon, Sylvie Freeman, Ban Dawood, Lozan Sheriff, Maelle Lorvellec, Jon Frampton & Paloma Garcia, 2012, In: Leukemia. 27, 3, p. 661-670 10 p.Research output: Contribution to journal › Article › peer-review
- 2011
- Published
Mesenchymal stem cells inhibit recruitment of flowing neutrophils and lymphocytes by endothelial cells: roles of interleukin-6 and transforming growth factor-{beta}
Christopher Buckley, Nguyet -Thin Luu, Philip Newsome, Jon Frampton & Gerard Nash, Oct 2011.Research output: Contribution to conference (unpublished) › Poster
- Published
c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation
Paloma Garcia & Jon Frampton, 1 Aug 2011, In: Journal of Thrombosis and Haemostasis. 9, 8, p. 1572-1581 10 p.Research output: Contribution to journal › Article › peer-review
- Published
Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region
Jon Frampton, 1 Jun 2011, In: The Journal of Experimental Medicine. 208, 6, p. 1305-1315 11 p.Research output: Contribution to journal › Article › peer-review
- Published
- Published
EMMPRIN (CD147/basigin) mediates platelet-monocyte interactions in vivo and augments monocyte recruitment to the vascular wall
Jon Frampton, 1 May 2011, In: Journal of Thrombosis and Haemostasis. 9, 5, p. 1007-1019 13 p.Research output: Contribution to journal › Article › peer-review
- Published
Professor Alan M Gewirtz (1949-2010) OBITUARY
Jon Frampton, 1 May 2011, In: Oncogene. 30, 19, p. 2187-2187 1 p.Research output: Contribution to journal › Article
- 2010
- Published
B-Myb is Critical for Proper Duplication During an Unperturbed s Phase in Mouse Embryonic Stem Cells.
Maelle Lorvellec, Stephanie Dumon, Jon Frampton & Paloma Garcia, 16 Aug 2010, In: Stem Cells. 28, 10, p. 1751-1759 9 p.Research output: Contribution to journal › Article › peer-review
- Published
Critical roles for c-Myb in lymphoid priming and early B-cell development
Jon Frampton, 1 Apr 2010, In: Blood. 115, 14, p. 2796-2805 10 p.Research output: Contribution to journal › Article
- Published
Platelets contribute to postnatal occlusion of the ductus arteriosus
Jon Frampton, 1 Jan 2010, In: Nature Medicine. 16, 1, p. 75-U111Research output: Contribution to journal › Article
- 2009
- Published
Evidence That Integrin alpha IIb beta 3-dependent Interaction of Mast Cells with Fibrinogen Exacerbates Chronic Inflammation
Jon Frampton, 1 Nov 2009, In: Journal of Biological Chemistry. 284, 45, p. 31463-31472 10 p.Research output: Contribution to journal › Article
- Published
Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors
Jon Frampton, 1 Jun 2009, In: Blood. 113, 23, p. 5783-5792 10 p.Research output: Contribution to journal › Article
- Published
Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basis.
Paloma Garcia, Mary Clarke, Oscar Berlanga, Maelle Lorvellec & Jon Frampton, 20 May 2009, In: The EMBO journal. 28, 10, p. 1492-504 13 p.Research output: Contribution to journal › Article › peer-review
- Published
The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development
Stephanie Dumon, Jon Frampton, 1 May 2009, In: Blood. 113, 22, p. 5456-5465 10 p.Research output: Contribution to journal › Article
- Published
Haematopoietic stem cell recruitment to injured murine liver sinusoids depends on alpha(4)beta(1) integrin/VCAM-1 interactions
Dean Kavanagh, Heather Beard, Trish Lalor, Jon Frampton, David Adams & Neena Kalia, 1 Jan 2009, In: Gut. 59, 1, p. 79-87 9 p.Research output: Contribution to journal › Article › peer-review
- Published
Platelet endothelial cell adhesion molecule (PECAM)-1 modulates SDF-1a/CXCR4 responses of hematopoietic stem cells
Ewan Ross, Sylvie Freeman, Tarvinder Dhanjal, Sian Lax, Zubair Ahmed, Tiezheng Hou, Stuart Egginton, Gerard Nash, Steve Watson, Jon Frampton & Christopher Buckley, 1 Jan 2009, p. 450. 1 p.Research output: Contribution to conference (unpublished) › Abstract
- 2008
- Published
A dual role for integrin-linked kinase in platelets: regulating integrin function and -granule secretion
Jon Frampton, 1 Dec 2008, In: Blood. 112, 12, p. 4523-4531 9 p.Research output: Contribution to journal › Article