Jon Frampton

Publications

  1. 2000
  2. Published

    The homeodomain protein PRH influences the differentiation of haematopoietic cells

    Padma-Sheela Jayaraman, Jon Frampton & , Dec 2000, In: Leukaemia Research. 24, 12, p. 1023-31 9 p.

    Research output: Contribution to journalArticlepeer-review

  3. 2001
  4. Published

    Myb oncogene

    Jon Frampton, 1 Jan 2001, Encyclopedia of Genetics.

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  5. Published
  6. Published

    The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen

    Steve Watson, , Ben Atkinson, Oscar Berlanga, , , , , , , , , & Jon Frampton, 1 Jul 2001, In: Journal of Thrombosis and Haemostasis. 86, 1, p. 276-88 13 p.

    Research output: Contribution to journalReview article

  7. Published

    Heterologous expression of the transcriptional repressor escargot inhibits megakaryocytic endomitosis

    Jon Frampton, & , 9 Nov 2001, In: Journal of Biological Chemistry. 276, p. 43413-43418 6 p.

    Research output: Contribution to journalArticle

  8. 2002
  9. Published
  10. Published

    Direct regulation of the bcl-2 gene by Fli-1 is involved in the survival of Fli-1-transformed erythroblasts

    Jon Frampton & , 15 Feb 2002, In: The EMBO journal. 21, 4, p. 694-703 10 p.

    Research output: Contribution to journalArticle

  11. Published

    The Fc receptor gamma-chain is necessary and sufficient to initiate signalling through glycoprotein VI

    Oscar Berlanga, , , , , Jon Frampton & , 1 Jun 2002, In: European Journal of Biochemistry. 269, 12, p. 2951-2960 10 p.

    Research output: Contribution to journalArticle

  12. 2003
  13. Published

    Manipulation of gene expression in megakaryocytes

    George Murphy, Jon Frampton, & , 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  14. Published

    Transcriptional regulation by c-Myb could be a major factor distinguishing the erythroid and megakaryocytic lineages

    Alexandros Vegiopoulos, , Jon Frampton & Jon Frampton, 1 Jan 2003, In Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  15. Published

    Using retroviruses to express genes in primary megakaryocyte lineage cells

    George Murphy, Jon Frampton, , & , 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  16. Published

    c-Myb is a key regulator of hematopoietic progenitor expansion and commitment

    Jon Frampton & Jon Frampton, 1 Jan 2003, In Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  17. Published

    Characterization of the c-Myb-responsive Region and Regulation of the Human Type I Collagen alpha 2 Chain Gene by c-Myb

    Jon Frampton, , , , , & , 10 Jan 2003, In: Journal of Biological Chemistry. 278, 3, p. 1533-1541 9 p.

    Research output: Contribution to journalArticle

  18. Published
  19. Published
  20. Published
  21. Published

    Murine GPVI stimulates weak integrin activation in PLC gamma 2-/- platelets: involvement of PLC gamma 1 and PI3-kinase

    Jon Frampton & Steve Watson, 1 Aug 2003, In: Blood. 102, 4, p. 1367-1373 7 p.

    Research output: Contribution to journalArticle

  22. Published
  23. Published

    Functional delivery of large genomic DNA to human cells with a peptide-lipid vector

    Jon Frampton, , , , & , 1 Oct 2003, In: Journal of Gene Medicine. 5, p. 883-892 10 p.

    Research output: Contribution to journalArticle

  24. Published
  25. 2004
  26. Published

    Myb Transcription Factors: Their Role in Growth, Differentiation and Disease

    Jon Frampton, 1 Jan 2004, Kluwer Academic Publishers.

    Research output: Book/ReportBook

  27. Published
  28. Published

    c-Myb and CREB function in adult neurogenesis

    Jon Frampton, & Jon Frampton, 1 Jan 2004, Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  29. Published
  30. Published
  31. Published
  32. 2005
  33. Published

    Expression and functional role for the GPIIb/GPIIIa integrin on bone marrow mast cells

    Oscar Berlanga, & Jon Frampton, 1 Jan 2005, In: Exp. Hematol. 33, p. 403-12 10 p.

    Research output: Contribution to journalArticle

  34. Published

    Selective impairment of platelet activation to collagen in the absence of GATA1

    Sascha Hughan, Yotis Senis, , , Jon Frampton, & Steve Watson, 1 Jun 2005, In: Blood. 105, p. 4369-76 8 p.

    Research output: Contribution to journalArticle

  35. Published
  36. Published
  37. Published

    Generation of a conditional allele of the B-myb gene

    Paloma Garcia, Oscar Berlanga, & Jon Frampton, 1 Dec 2005, In: Genesis. 43, p. 189-95 7 p.

    Research output: Contribution to journalArticle

  38. 2006
  39. Published
  40. Published
  41. Published
  42. Published
  43. Published

    Coordination of erythropoiesis by the transcription factor c-Myb

    Alexandros Vegiopoulos, Paloma Garcia, & Jon Frampton, 15 Jun 2006, In: Blood. 107, 12, p. 4703-10 8 p.

    Research output: Contribution to journalArticle

  44. Published

    c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells

    Jon Frampton & , 1 Jul 2006, In: Blood. 108, 1, p. 297-304 8 p.

    Research output: Contribution to journalArticle

  45. Published

    Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development

    Jon Frampton & , 1 Aug 2006, In: Blood. 108, 3, p. 896-903 8 p.

    Research output: Contribution to journalArticle

  46. Published

    Targeting an E2F site in the mouse genome prevents promoter silencing in quiescent and post-mitotic cells

    Fiona Tavner, Jon Frampton & , 30 Oct 2006, In: Oncogene. 26, 19, p. 2727-35 9 p.

    Research output: Contribution to journalArticle

  47. Published
  48. 2007
  49. Published

    Regulation of erythropoiesis by the neuronal transmembrane protein Lrfn2

    Jon Frampton & , 1 Jan 2007, In: Experimental Hematology. 35, 5, p. 724-734 11 p.

    Research output: Contribution to journalArticle

  50. Published

    c-Myb is required for progenitor cell homeostasis in colonic crypts

    John Heath, Jon Frampton, , , , & , 6 Mar 2007, In: National Academy of Sciences. Proceedings. 104, 10, p. 3829-34 6 p.

    Research output: Contribution to journalArticle

  51. Published

    Glycoprotein VI oligomerization in cell lines and platelets

    Oscar Berlanga, , , Jon Frampton, , Michael Tomlinson & Steve Watson, 1 May 2007, In: Journal of Thrombosis and Haemostasis. 5, 5, p. 1026-33 8 p.

    Research output: Contribution to journalArticle

  52. Published

    c-Myb Is Required for Neural Progenitor Cell Proliferation and Maintenance of the Neural Stem Cell Niche in Adult Brain

    Jon Frampton & , 29 Nov 2007, In: Stem Cells. 26, 1, p. 173-81 9 p.

    Research output: Contribution to journalArticle

  53. 2008
  54. Published

    c-Myb-Dependent Smooth Muscle Cell Differentiation

    Jon Frampton, , & , 14 Mar 2008, In: Circulation Research. 102, 5, p. 554-561 8 p.

    Research output: Contribution to journalArticle

  55. Published
  56. Published
  57. Published
  58. Published

    A dual role for integrin-linked kinase in platelets: regulating integrin function and  -granule secretion

    Jon Frampton, & , 1 Dec 2008, In: Blood. 112, 12, p. 4523-4531 9 p.

    Research output: Contribution to journalArticle

  59. Published

    Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

    Jon Frampton, , , , , & , 1 Dec 2008, In: Blood. 112, 12, p. 4512-4522 11 p.

    Research output: Contribution to journalArticle

  60. 2009
  61. Published
  62. Published
  63. Published

    The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development

    Stephanie Dumon, Jon Frampton, , , , & , 1 May 2009, In: Blood. 113, 22, p. 5456-5465 10 p.

    Research output: Contribution to journalArticle

  64. Published

    Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basis.

    Paloma Garcia, Mary Clarke, , Oscar Berlanga, , Maelle Lorvellec & Jon Frampton, 20 May 2009, In: The EMBO journal. 28, 10, p. 1492-504 13 p.

    Research output: Contribution to journalArticlepeer-review

  65. Published
  66. Published
  67. 2010
  68. Published

    Platelets contribute to postnatal occlusion of the ductus arteriosus

    Jon Frampton, , , , , , , & , 1 Jan 2010, In: Nature Medicine. 16, 1, p. 75-U111

    Research output: Contribution to journalArticle

  69. Published

    Critical roles for c-Myb in lymphoid priming and early B-cell development

    Jon Frampton, , & , 1 Apr 2010, In: Blood. 115, 14, p. 2796-2805 10 p.

    Research output: Contribution to journalArticle

  70. Published

    B-Myb is Critical for Proper Duplication During an Unperturbed s Phase in Mouse Embryonic Stem Cells.

    Maelle Lorvellec, Stephanie Dumon, , , Jon Frampton & Paloma Garcia, 16 Aug 2010, In: Stem Cells. 28, 10, p. 1751-1759 9 p.

    Research output: Contribution to journalArticlepeer-review

  71. 2011
  72. Published
  73. Published

    Professor Alan M Gewirtz (1949-2010) OBITUARY

    Jon Frampton, & , 1 May 2011, In: Oncogene. 30, 19, p. 2187-2187 1 p.

    Research output: Contribution to journalArticle

  74. Published

    Development of a multi-view, multi-spectral bioluminescence tomography small animal imaging system

    Hamid Dehghani, Hector Basevi, Iain Styles, Jon Frampton, & , 22 May 2011, p. 80881K.

    Research output: Contribution to conference (unpublished)Paper

  75. Published

    Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

    Jon Frampton, & , 1 Jun 2011, In: The Journal of Experimental Medicine. 208, 6, p. 1305-1315 11 p.

    Research output: Contribution to journalArticlepeer-review

  76. Published

    c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation

    Paloma Garcia, , , & Jon Frampton, 1 Aug 2011, In: Journal of Thrombosis and Haemostasis. 9, 8, p. 1572-1581 10 p.

    Research output: Contribution to journalArticlepeer-review

  77. Published
  78. 2012
  79. Published
  80. Published
  81. Published

    A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

    Jon Frampton, & , 1 Apr 2012, In: Science. 336, 6077, p. 86-90 5 p.

    Research output: Contribution to journalArticlepeer-review

  82. Published
  83. Published
  84. Published
  85. 2013
  86. Published

    Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level

    Jon Frampton, , , & , 2013, In: Nature Communications. 4, p. 2924

    Research output: Contribution to journalArticlepeer-review

  87. Published
  88. Published
  89. Published

    C/EBPα and MYB regulate FLT3 expression in AML

    Giacomo Volpe, , , Paloma Garcia, Emilie Dasse, Laura O'Neill, , Jon Frampton & Stephanie Dumon, 23 Jan 2013, In: Leukemia. 27, 7, p. 1487-1496 10 p.

    Research output: Contribution to journalArticlepeer-review

  90. Published

    Bioluminescence tomography improves quantitative accuracy for pre-clinical imaging

    Hector Basevi, Hamid Dehghani, Iain Styles & Jon Frampton, 25 Jun 2013, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  91. Published

    Multi-modal molecular diffuse optical tomography system for small animal imaging

    Hector Basevi, Jon Frampton, Iain Styles & Hamid Dehghani, 10 Sep 2013, In: Measurement Science and Technology. 24, 10, 22 p., 105405.

    Research output: Contribution to journalArticlepeer-review

  92. Published
  93. 2014
  94. Published

    Generation of knockout rabbits using transcription activator-like effector nucleases

    Philip Newsome, Jon Frampton, & , 5 Feb 2014, In: Cell Regeneration . 3, 3.

    Research output: Contribution to journalArticlepeer-review

  95. Published

    RAG1/2 knockout pigs with severe combined immunodeficiency

    Jon Frampton, , , & , 1 Aug 2014, In: Journal of Immunology. 193, 3, p. 1496-503 8 p.

    Research output: Contribution to journalArticlepeer-review

  96. Published

    Transcriptional pause release is a rate-limiting step for somatic cell reprogramming

    Yuan Li & 12 others, , , Jon Frampton, , , , , , , , & , 6 Nov 2014, In: Cell stem cell. 15, 5, p. 574-88 15 p.

    Research output: Contribution to journalArticlepeer-review

  97. 2015
  98. Published
  99. Published

    Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes

    Paloma Garcia, , Jon Frampton & , Feb 2015, In: Stem Cells. 33, 2, p. 479-490 12 p.

    Research output: Contribution to journalArticlepeer-review

  100. Published

    Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development

    Kate Lowe, Brenda Finney, , , , Jon Frampton, Christopher Buckley, , , & Steve Watson, 11 Jun 2015, In: Blood. 125, 24, p. 3769-3777 9 p.

    Research output: Contribution to journalArticlepeer-review

  101. Published
  102. Published
  103. Published

    Fibrin activates GPVI in human and mouse platelets

    Craig Hughes, , , Jon Frampton, & Steve Watson, 24 Sep 2015, In: Blood. 126, 13, p. 1601-1608 8 p.

    Research output: Contribution to journalArticlepeer-review

  104. E-pub ahead of print

    Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction

    Emilie Dasse, , , , , , , , , , , Jon Frampton & , 2 Dec 2015, (E-pub ahead of print) In: Blood.

    Research output: Contribution to journalArticlepeer-review

  105. 2016
  106. E-pub ahead of print
  107. 2017
  108. Published

    Targeting the transcription factor Myb by small-molecule inhibitors

    Jon Frampton & , 1 Mar 2017, In: Experimental Hematology. 47, p. 31-35

    Research output: Contribution to journalArticlepeer-review

  109. Published

    Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1

    Philip Newsome, Jon Frampton & 4 others, , , & , 17 Mar 2017, In: Journal of Biological Chemistry. 292, 11, p. 4755-4763 9 p.

    Research output: Contribution to journalArticlepeer-review

  110. Published
  111. 2018
  112. Published

    Harnessing genomics to improve outcomes for women with cancer in India: key priorities for research

    Sudha Sundar, Jean-Baptiste Cazier & Jon Frampton, 15 Feb 2018, In: The Lancet Oncology. 19, 2, p. e102–e112

    Research output: Contribution to journalArticlepeer-review

  113. Published

    Inducible disruption of the c-myb gene allows allogeneic bone marrow transplantation without irradiation

    Jon Frampton, & , 1 Jun 2018, In: Journal of Immunological Methods. 457, p. 66-72

    Research output: Contribution to journalArticlepeer-review

  114. Published
  115. Published

    Fine-tuning Mybl2 is required for proper mesenchymal-to-epithelial transition during somatic reprogramming

    Carl Ward, Giacomo Volpe, Pierre Cauchy, Anetta Ptasinska, , , , , Jon Frampton, , , & Paloma Garcia, 7 Aug 2018, In: Cell Reports. 24, 6, p. 1496-1511.e8 24 p.

    Research output: Contribution to journalArticlepeer-review

  116. 2019
  117. Published

    CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex

    Giacomo Volpe, Jon Frampton, , , & , Jul 2019, In: Leukemia. 33, p. 1608-1619 12 p.

    Research output: Contribution to journalArticlepeer-review

  118. 2020
  119. Published
  120. Published