Jon Frampton
Publications
- Published
Human mesenchymal stem cells are recruited to injured liver in a β1-integrin and CD44 dependent manner
Victoria Day, Abhilok Garg, Nick Davies, David Bartlett, Heather Beard, Dean Kavanagh, Neena Kalia, Jon Frampton, Trish Lalor & Philip Newsome, 1 Sep 2012, In: Hepatology. 56, 3, p. 1063-1073 11 p.Research output: Contribution to journal › Article › peer-review
- Published
Fibrin activates GPVI in human and mouse platelets
Craig Hughes, Jon Frampton & Steve Watson, 24 Sep 2015, In: Blood. 126, 13, p. 1601-1608 8 p.Research output: Contribution to journal › Article › peer-review
- Published
Heterologous expression of the transcriptional repressor escargot inhibits megakaryocytic endomitosis
Jon Frampton, 9 Nov 2001, In: Journal of Biological Chemistry. 276, p. 43413-43418 6 p.Research output: Contribution to journal › Article
- Published
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters
Jon Frampton & 1 others, , Jan 2015, In: Cell Research. 25, 1, p. 80-92 13 p.Research output: Contribution to journal › Article › peer-review
- Published
Professor Alan M Gewirtz (1949-2010) OBITUARY
Jon Frampton, 1 May 2011, In: Oncogene. 30, 19, p. 2187-2187 1 p.Research output: Contribution to journal › Article
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Expression and functional role for the GPIIb/GPIIIa integrin on bone marrow mast cells
Oscar Berlanga & Jon Frampton, 1 Jan 2005, In: Exp. Hematol. 33, p. 403-12 10 p.Research output: Contribution to journal › Article
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- Published
The Fc receptor gamma-chain is necessary and sufficient to initiate signalling through glycoprotein VI
Oscar Berlanga, Jon Frampton, 1 Jun 2002, In: European Journal of Biochemistry. 269, 12, p. 2951-2960 10 p.Research output: Contribution to journal › Article
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Mesenchymal stem cells inhibit recruitment of flowing neutrophils and lymphocytes by endothelial cells: roles of interleukin-6 and transforming growth factor-{beta}
Christopher Buckley, Nguyet -Thin Luu, Philip Newsome, Jon Frampton & Gerard Nash, Oct 2011.Research output: Contribution to conference (unpublished) › Poster
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Regulation of erythropoiesis by the neuronal transmembrane protein Lrfn2
Jon Frampton, 1 Jan 2007, In: Experimental Hematology. 35, 5, p. 724-734 11 p.Research output: Contribution to journal › Article
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MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia
Stephanie Dumon, Sylvie Freeman, Ban Dawood, Lozan Sheriff, Maelle Lorvellec, Jon Frampton & Paloma Garcia, 2012, In: Leukemia. 27, 3, p. 661-670 10 p.Research output: Contribution to journal › Article › peer-review
- E-pub ahead of print
Transcriptional regulation of SPROUTY 2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3
Mary Clarke, Giacomo Volpe, Lozan Sheriff, Carl Ward, Wenbin Wei, Stephanie Dumon, Paloma Garcia & Jon Frampton, 8 Nov 2016, In: Leukemia.Research output: Contribution to journal › Article › peer-review
- Published
Distinct regulation of c-myb gene expression by HoxA9, Meis1 and Pbx proteins in normal hematopoietic progenitors and transformed myeloid cells
Emilie Dasse, Giacomo Volpe, Doug Walton, Neil Wilson, Walter Del Pozzo, Laura O'Neill, Jon Frampton & Stephanie Dumon, Jun 2012, In: Blood Cancer Journal. 2, 6, p. e76Research output: Contribution to journal › Article › peer-review
- Published
- Published
Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6
Stephanie Dumon, Victoria Heath, Michael Tomlinson & Jon Frampton, 1 May 2006, In: Experimental Hematology. 34, 5, p. 654-63 10 p.Research output: Contribution to journal › Article
- Published
Platelets contribute to postnatal occlusion of the ductus arteriosus
Jon Frampton, 1 Jan 2010, In: Nature Medicine. 16, 1, p. 75-U111Research output: Contribution to journal › Article
- Published
Manipulation of gene expression in megakaryocytes
George Murphy, Jon Frampton, 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
- Published
The glycoprotein IIb molecule is expressed on early murine hematopoietic progenitors and regulates their numbers in sites of hematopoiesis
Jon Frampton, 1 Jul 2003, In: Immunity. 19, p. 33-45 13 p.Research output: Contribution to journal › Article
- Published
c-Myb is a key regulator of hematopoietic progenitor expansion and commitment
Jon Frampton & Jon Frampton, 1 Jan 2003, In Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
Comparative gene analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster
Jon Frampton, 1 Feb 2001, In: Human Molecular Genetics. 10, p. 371-382 12 p.Research output: Contribution to journal › Article
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Myb Transcription Factors: Their Role in Growth, Differentiation and Disease
Jon Frampton, 1 Jan 2004, Kluwer Academic Publishers.Research output: Book/Report › Book
- Published
Myb oncogene
Jon Frampton, 1 Jan 2001, Encyclopedia of Genetics.Research output: Chapter in Book/Report/Conference proceeding › Entry for encyclopedia/dictionary
- Published
Hematopoietic lineage commitment: miRNAs add specificity to a widely expressed transcription factor
Paloma Garcia & Jon Frampton, 1 Jun 2008, In: Developmental Cell. 14, 6, p. 815-6 2 p.Research output: Contribution to journal › Article
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c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation
Paloma Garcia & Jon Frampton, 1 Aug 2011, In: Journal of Thrombosis and Haemostasis. 9, 8, p. 1572-1581 10 p.Research output: Contribution to journal › Article › peer-review
- Published
The transcription factor B-Myb is essential for S phase progression and genomic stability in both diploid and polyploid megakaryocytes
Paloma Garcia & Jon Frampton, 15 Apr 2006, In: Journal of Cell Science. 119, p. 1483-1493 11 p.Research output: Contribution to journal › Article
- Published
Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basis.
Paloma Garcia, Mary Clarke, Oscar Berlanga, Maelle Lorvellec & Jon Frampton, 20 May 2009, In: The EMBO journal. 28, 10, p. 1492-504 13 p.Research output: Contribution to journal › Article › peer-review
- Published
Generation of a conditional allele of the B-myb gene
Paloma Garcia, Oscar Berlanga & Jon Frampton, 1 Dec 2005, In: Genesis. 43, p. 189-95 7 p.Research output: Contribution to journal › Article
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Using retroviruses to express genes in primary megakaryocyte lineage cells
George Murphy, Jon Frampton, 1 Jan 2003, In Platelets and Megakaryocytes: Methods and Protocols.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
The scl+19 cell enhancer is not required for haematopoiesis: identification of a second bifunctional hematopoietic/endothelial enhancer regulated by Fil-1 and Elf-1
George Murphy, Jon Frampton, 1 Jan 2004, In: Molecular and Cellular Biology. 24, p. 1870-1883 14 p.Research output: Contribution to journal › Article
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Critical roles for c-Myb in lymphoid priming and early B-cell development
Jon Frampton, 1 Apr 2010, In: Blood. 115, 14, p. 2796-2805 10 p.Research output: Contribution to journal › Article
- Published
- Published
Multi-modal molecular diffuse optical tomography system for small animal imaging
Hector Basevi, Jon Frampton, Iain Styles & Hamid Dehghani, 10 Sep 2013, In: Measurement Science and Technology. 24, 10, 22 p., 105405.Research output: Contribution to journal › Article › peer-review
- Published
Bioluminescence tomography improves quantitative accuracy for pre-clinical imaging
Hector Basevi, Hamid Dehghani, Iain Styles & Jon Frampton, 25 Jun 2013, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8799.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility
Jon Frampton, 15 Apr 2004, In: Genes and Immunity. 5, p. 274-82 9 p.Research output: Contribution to journal › Article
- Published
The TspanC8 subgroup of tetraspanins interacts with a disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression
Elizabeth Haining, Steve Watson, Jon Frampton, Paloma Garcia & Michael Tomlinson, 16 Nov 2012, In: Journal of Biological Chemistry. 287, 47, p. 39753-39765 13 p.Research output: Contribution to journal › Article › peer-review
- Published
c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells
Jon Frampton, 1 Jul 2006, In: Blood. 108, 1, p. 297-304 8 p.Research output: Contribution to journal › Article
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RAG1/2 knockout pigs with severe combined immunodeficiency
Jon Frampton, 1 Aug 2014, In: Journal of Immunology. 193, 3, p. 1496-503 8 p.Research output: Contribution to journal › Article › peer-review
- Published
Selective impairment of platelet activation to collagen in the absence of GATA1
Sascha Hughan, Yotis Senis, Jon Frampton & Steve Watson, 1 Jun 2005, In: Blood. 105, p. 4369-76 8 p.Research output: Contribution to journal › Article
- Published
The homeodomain protein PRH influences the differentiation of haematopoietic cells
Padma-Sheela Jayaraman, Jon Frampton, Dec 2000, In: Leukaemia Research. 24, 12, p. 1023-31 9 p.Research output: Contribution to journal › Article › peer-review
- Published
Enhancing the adhesion of haematopoietic precursor cell integrins with hydrogen peroxide increases recruitment within murine gut
Dean Kavanagh, Adrian Yemm, Jon Frampton & Neena Kalia, 2013, In: Cell transplantation. 22, 8, p. 1485-1499 15 p.Research output: Contribution to journal › Article › peer-review
- Published
Haematopoietic stem cell recruitment to injured murine liver sinusoids depends on alpha(4)beta(1) integrin/VCAM-1 interactions
Dean Kavanagh, Heather Beard, Trish Lalor, Jon Frampton, David Adams & Neena Kalia, 1 Jan 2009, In: Gut. 59, 1, p. 79-87 9 p.Research output: Contribution to journal › Article › peer-review
- Published
Mechanisms of adhesion and subsequent actions of a haematopoietic stem cell line, HPC-7, in the injured murine intestinal microcirculation in vivo
Dean Kavanagh, Adrian Yemm, Yan Zhao, Jon Frampton & Neena Kalia, 2013, In: PLoS ONE. 8, 3, p. e59150Research output: Contribution to journal › Article › peer-review
- Published
Pretreatment of Mesenchymal Stem Cells Manipulates Their Vasculoprotective Potential While Not Altering Their Homing Within the Injured Gut
Dean Kavanagh, Philip Newsome, Jon Frampton & Neena Kalia, 24 Aug 2015, In: Stem Cells. 33, 9, p. 2785-97 13 p.Research output: Contribution to journal › Article › peer-review
- Published
The Evi-1 proto-oncoprotein blocks endomitosis in megakaryocytes by inhibiting sustained cyclin-dependent kinase 2 catalytic activity
Jon Frampton, 1 Sep 2005, In: British Journal of Haematology. 130, p. 902-11 10 p.Research output: Contribution to journal › Article
- Published
c-Myb-Dependent Smooth Muscle Cell Differentiation
Jon Frampton, 14 Mar 2008, In: Circulation Research. 102, 5, p. 554-561 8 p.Research output: Contribution to journal › Article
- Published
Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors
Jon Frampton, 1 Jun 2009, In: Blood. 113, 23, p. 5783-5792 10 p.Research output: Contribution to journal › Article
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Direct regulation of the bcl-2 gene by Fli-1 is involved in the survival of Fli-1-transformed erythroblasts
Jon Frampton, 15 Feb 2002, In: The EMBO journal. 21, 4, p. 694-703 10 p.Research output: Contribution to journal › Article
- Published
Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1
Philip Newsome, Jon Frampton & 4 others, , 17 Mar 2017, In: Journal of Biological Chemistry. 292, 11, p. 4755-4763 9 p.Research output: Contribution to journal › Article › peer-review
- Published
Transcriptional pause release is a rate-limiting step for somatic cell reprogramming
Yuan Li & 12 others, , 6 Nov 2014, In: Cell stem cell. 15, 5, p. 574-88 15 p.Research output: Contribution to journal › Article › peer-review