John Curnow

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Publications

  1. 2021
  2. Published

    Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation

    Alexander Roberts, Tina Tang, Chiara Pallini, Graham Wallace, Alison Cooper, Aaron Scott, David Thickett, Sebastian Lugg, Thomas Pinkney, Graham Taylor, Kristian Brock, Zania Stamataki, John Curnow, John Gordon, Omar Qureshi, Nicholas Barnes & 7 others, , 17 Feb 2021, In: Scientific Reports. 11, 4030.

    Research output: Contribution to journal › Article › peer-review

  3. 2018
  4. E-pub ahead of print

    Cerebrospinal fluid immunoglobulin light chain ratios predict disease progression in multiple sclerosis

    John Curnow, Ghaniah Hassan-Smith & Michael Douglas, 9 May 2018, In: Journal of Neurology, Neurosurgery & Psychiatry.

    Research output: Contribution to journal › Article › peer-review

  5. 2017
  6. Published

    N-glycosylation and expression in human tissues of the orphan GPR61 receptor

    Gillian Grafton, Alison Cooper, John Curnow & Nicholas Barnes, 1 Dec 2017, In: FEBS Open Bio. 7, 12, p. 1982-1993 12 p.

    Research output: Contribution to journal › Article › peer-review

  7. Published

    CCR6+ Th cells in the cerebrospinal fluid of persons with multiple sclerosis are dominated by pathogenic non-classic Th1 cells and GM-CSF-only-secreting Th cells

    Ghaniah Hassan-Smith, Michael Douglas & John Curnow, Aug 2017, In: Brain, Behaviour, and Immunity. 64, p. 71-79

    Research output: Contribution to journal › Article › peer-review

  8. Published

    Inosine Acedoben Dimepranol promotes an early and sustained increase in the natural killer cell component of circulating lymphocytes: a clinical trial supporting anti-viral indications

    Amy Newman, Gillian Grafton, John Curnow, Nicholas Barnes & John Gordon, Jan 2017, In: International Immunopharmacology. 42, p. 108-114

    Research output: Contribution to journal › Article › peer-review

  9. 2016
  10. Published

    Conjunctival neutrophils predict progressive scarring in Ocular Mucous Membrane Pemphigoid

    John Curnow & Saaeha Rauz, 1 Oct 2016, In: Investigative Ophthalmology & Visual Science (IOVS). 57, 13, p. 5457-5469

    Research output: Contribution to journal › Article › peer-review

  11. 2015
  12. E-pub ahead of print

    Novel vitamin D analogues; cytotoxic and anti-proliferative activity against a diffuse large B-cell lymphoma cell line and B-cells from healthy donors

    Gillian Grafton, John Curnow & Nicholas Barnes, 17 Oct 2015, In: The Journal of Steroid Biochemistry and Molecular Biology.

    Research output: Contribution to journal › Article › peer-review

  13. Published

    Association analysis of TGFBR3 gene with Behçet's disease and idiopathic intermediate uveitis in a Caucasian population

    Robert Barry, Phil Murray, John Curnow & Graham Wallace, May 2015, In: British Journal of Ophthalmology. 99, 5, p. 696-9 4 p.

    Research output: Contribution to journal › Article › peer-review

  14. 2014
  15. Published

    Cytokine production and antigen recognition by human mucosal homing conjunctival effector memory CD8+ T cells

    Geraint Williams, Annette Pachnio, Heather Long, Saaeha Rauz & John Curnow, 29 Dec 2014, In: Investigative Ophthalmology & Visual Science (IOVS). 55, 12, p. 8523-8530 8 p.

    Research output: Contribution to journal › Article › peer-review

  16. Published

    High sensitivity and specificity of elevated cerebrospinal fluid kappa free light chains in suspected multiple sclerosis

    Ghaniah Hassan-Smith, Lakhvir Assi, Jeffrey Faint, Michael Douglas & John Curnow, 15 Nov 2014, In: Journal of Neuroimmunology. 276, 1-2, p. 175-179 5 p.

    Research output: Contribution to journal › Article › peer-review

  17. 2013
  18. Published

    Elevation of conjunctival epithelial CD45INTCD11b⁺CD16⁺CD14⁻ neutrophils in ocular Stevens-Johnson syndrome and toxic epidermal necrolysis

    Geraint Williams, Paul Tomlins, Alastair Denniston, John Curnow & Saaeha Rauz, 10 Jul 2013, In: Investigative Ophthalmology & Visual Science (IOVS). 54, 7, p. 4578-4585

    Research output: Contribution to journal › Article › peer-review

  19. Published

    Cell-intrinsic regulation of murine dendritic cell function and survival by pre-receptor amplification of glucocorticoid

    Annelise Soulier, Elizabeth Rabbitt, Paul Stewart, Gareth Lavery, John Curnow & Ronjon Chakraverty, 2013, In: Blood.

    Research output: Contribution to journal › Article › peer-review

  20. 2012
  21. Published

    The dominant human conjunctival epithelial CD8αβ+ T cell population is maintained with age but the number of CD4+ T cells increases

    Geraint Williams, Alastair Denniston, Paul Tomlins, Robert Barry, Saaeha Rauz & John Curnow, 1 Dec 2012, In: Age (Dordrecht, Netherlands). 34, 6, p. 1517-1528

    Research output: Contribution to journal › Article › peer-review

  22. Published

    Aqueous Humor Suppression of Dendritic Cell Function Helps Maintain Immune Regulation in the Eye during Human Uveitis.

    Alastair Denniston, Paul Tomlins, Geraint Williams, Graham Wallace, Saaeha Rauz, Phil Murray & John Curnow, 1 Jan 2012, In: Investigative Ophthalmology & Visual Science (IOVS). 53, 2, p. 888-96 9 p.

    Research output: Contribution to journal › Article

  23. 2011
  24. Published

    The response of T cells to interleukin-6 is differentially regulated by the microenvironment of the rheumatoid synovial fluid and tissue

    Esther Hidalgo, Sarah Essex, Lorraine Yeo, John Curnow, Andrew Filer, Mark Cooper, Helen McGettrick, Mike Salmon, Christopher Buckley, Karim Raza & Dagmar Scheel-Toellner, 1 Nov 2011, In: Arthritis & Rheumatism. 63, 11, p. 3284-93 10 p.

    Research output: Contribution to journal › Article › peer-review

  25. Published

    A systems biology approach identifies molecular networks defining skeletal muscle abnormalities in chronic obstructive pulmonary disease

    John Curnow, Laura O'Neill, Stuart Egginton & Francesco Falciani, 1 Sep 2011, In: PLoS Computational Biology. 7, 9, p. e1002129

    Research output: Contribution to journal › Article

  26. Published

    Bridging innate and adaptive immunity: removing the toll

    John Curnow & Graham Wallace, 1 Aug 2011, In: Current Opinion in Pharmacology. 11, 4, p. 395-396 2 p.

    Research output: Contribution to journal › Editorial

  27. Published

    Intraocular immune mechanisms in Uveitis

    John Curnow, Alastair Denniston, Phil Murray & Graham Wallace, 1 Aug 2011, In: Current Immunology Reviews. 7, 3, p. 350-359 10 p.

    Research output: Contribution to journal › Review article › peer-review

  28. Published

    The stromal cell antigen CD248 (endosialin) is expressed on naive CD8(+) human T cells and regulates proliferation.

    Debbie Hardie, Amy Naylor, Tiezheng Hou, Sian Lax, John Curnow & Christopher Buckley, Jul 2011, In: Immunology. 133, 3, p. 288-295 8.

    Research output: Contribution to journal › Article › peer-review

  29. Published

    Validation of a fornix depth measurer : a putative tool for the assessment of progressive cicatrising conjunctivitis

    Geraint Williams, John Curnow, Peter Nightingale & Saaeha Rauz, Jun 2011, In: British Journal of Ophthalmology. 95, 6, p. 842-847 6 p.

    Research output: Contribution to journal › Article › peer-review

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