Grant Stewart

Colleges, School and Institutes

Willingness to take PhD students

Yes

PhD projects

Professor Stewart is interested in supervising doctoral research on:

Regulation of the cellular response to DNA damage by the ubiquitin/SUMO system
Identification of novel human disease genes involved in the repair of DNA damage by total genome sequencing
Functional regulation of the DNA damage response by phosphorylation/dephosphorylation

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Most downloaded publications

USP7 is essential for maintaining Rad18 stability and DNA damage tolerance
Anastasia Zlatanou, Grant Stewart, Angelo Agathanggelou, Tatjana Stankovic & Miller, E., 2015, In : Oncogene.

Research output: Contribution to journal › Article

214 downloads
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
Grant Stewart, Martin Higgs & Anastasia Zlatanou, 2016, In : Nature Genetics. 48, p. 36-43

Research output: Contribution to journal › Article

197 downloads
BRCA2 and RAD51 promote double-strand break formation and cell death in response to Gemcitabine
Rebecca Jones, Panagiotis Kotsantis, Grant Stewart, Groth, P. & Eva Petermann, Oct 2014, In : Molecular Cancer Therapeutics. 13, 10, p. 2412-2421

Research output: Contribution to journal › Article

81 downloads
BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia
Da Costa, D., Angelo Agathanggelou, Perry, T., Victoria Weston, Eva Petermann, Anastasia Zlatanou, Ceri Oldreive, Wenbin Wei, Grant Stewart, Longman, J., Emma Smith, Pamela Kearns, Knapp, S. & Tatjana Stankovic, Jul 2013, In : Blood Cancer Journal. 3, 7, e126.

Research output: Contribution to journal › Article

55 downloads
Bod1l is required to suppress deleterious resection of stressed replication forks
Martin Higgs, John Reynolds, Winczura, A., Blackford, AN., Borel, V., Miller, E., Anastasia Zlatanou, Nieminuszczy, J., Ryan, E., Nicholas Davies, Tatjana Stankovic, Boulton, S., Niedzwiedz, W. & Grant Stewart, 6 Aug 2015, In : Molecular Cell. 59, 3, p. 462-477

Research output: Contribution to journal › Article

47 downloads

Recent publications

Biallelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes
Burrage, L., Reynolds, J., Baratang, N., Phillips, J., Wegner, J., McFarquhar, A., Higgs, M., Christiansen, A., Lanza, D., Seavitt, J., Jain, M., Li, X., Parry, D., Raman, V., Chitayat, D., Chinn, I., Bertuch, A., Karaviti, L., Schlesinger, A., Earl, D. & 39 othersBamshad, M., Savarirayan, R., Doddapaneni, H., Muzny, D., Jhangiani, S., Eng, C., Gibbs, R., Bi, W., Emrick, L., Rosenfeld, J., Postlethwait, J., Westerfield, M., Dickinson, M., Beaudet, A., Ranza, E., Huber, C., Cormier-Daire, V., Shen, W., Mao, R., Heaney, J., Orange, J., Undiagnosed Diseases Network, Bertola, D., Yamamoto, G., Baratela, W., Butler, M., Ali, A., Adeli, M., Cohn, D., Krakow, D., Jackson, A., Lees, M., Offiah, A., Carlston, C., Carey, J., Grant Stewart, Bacino, C., Campeau, P. & Lee, B., 17 Jan 2019, (Accepted/In press) In : American Journal of Human Genetics.

Research output: Contribution to journal › Article

MYBL2 supports DNA double strand break repair in haematopoietic stem cells
Rachel Bayley, Blakemore, D., Cancian, L., Stephanie Dumon, Giacomo Volpe, Carl Ward, Al Maghrabi, R., Gujar, J., Reeve, N., Manoj Raghavan, Martin Higgs, Grant Stewart, Eva Petermann & Paloma Garcia, Oct 2018, In : Cancer Research. 78, 20

Research output: Contribution to journal › Article

Histone methylation by SETD1A protects nascent DNA through the nucleosome chaperone activity of FANCD2
Martin Higgs, Sato, K., John Reynolds, Shabana Begum, Rachel Bayley, Goula, A., Vernet, A., Paquin, K., Skalnik, D., Kobayashi, W., Takata, M., Howlett, N., Kurumizaka, H., Kimura, H. & Grant Stewart, 5 Jul 2018, In : Molecular Cell. 71, 1, p. 25-41

Research output: Contribution to journal › Article

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