Grant Stewart

Colleges, School and Institutes

Willingness to take PhD students

Yes

PhD projects

Professor Stewart is interested in supervising doctoral research on:

Regulation of the cellular response to DNA damage by the ubiquitin/SUMO system
Identification of novel human disease genes involved in the repair of DNA damage by total genome sequencing
Functional regulation of the DNA damage response by phosphorylation/dephosphorylation

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Most downloaded publications

USP7 is essential for maintaining Rad18 stability and DNA damage tolerance
Anastasia Zlatanou, Grant Stewart, Angelo Agathanggelou, Tatjana Stankovic & Miller, E., 2015, In : Oncogene.

Research output: Contribution to journal › Article

356 downloads
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
Grant Stewart, Martin Higgs & Anastasia Zlatanou, 2016, In : Nature Genetics. 48, p. 36-43

Research output: Contribution to journal › Article

303 downloads
BRCA2 and RAD51 promote double-strand break formation and cell death in response to Gemcitabine
Rebecca Jones, Panagiotis Kotsantis, Grant Stewart, Groth, P. & Eva Petermann, Oct 2014, In : Molecular Cancer Therapeutics. 13, 10, p. 2412-2421

Research output: Contribution to journal › Article

127 downloads
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism
John Reynolds, Martin Higgs, Anastasia Zlatanou, Vernet, A., Malcolm Taylor & Grant Stewart, 2017, In : Nature Genetics. 49, p. 537–549

Research output: Contribution to journal › Article

126 downloads
PRMT5-dependent methylation of the TIP60 coactivator RUVBL1 is a key regulator of homologous recombination
Clare Davies, Grant Stewart, John Reynolds, Clarke, T., Pilar Sanchez-Bailon, Kelly Chiang, Joaquin Andres Herrero Ruiz, Banderias, T., Matias, P., Maslen, S. & Shekel, M., 2 Mar 2017, In : Molecular Cell. 65, 2, p. 900–916.e7

Research output: Contribution to journal › Article

94 downloads

Recent publications

Isomerization of BRCA1-BARD1 promotes replication fork protection
Manuel Daza Martin, Katarzyna Starowicz, Mohammed Jamshad, Tye, S., George Ronson, Hannah Mackay, Anoop Chauhan, Alexa Walker, Stone, H. R., James Beesley, Coles, J. L., Alexander Garvin, Grant Stewart, McCorvie, T. J., Zhang, X., Ruth Densham & Jo Morris, 3 Jul 2019, In : Nature.

Research output: Contribution to journal › Article

Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia
Chang, H. R., Cho, S. Y., Lee, J. H., Lee, E., Soo, J., Lee, H. R., Cavalcanti, D. P., Mäkitie, O., Valta, H., Girisha, K. M., Lee, C., Neethukrishna, K., Bhavani, G. S., Shukla, A., Nampoothiri, S., Phadke, S. R., Park, M. J., Ikegawa, S., Wang, Z., Higgs, M. & 15 others, Grant Stewart, Jung, E., Lee, M-S., Park, J. H., Lee, E. A., Kim, H., Myung, K., Jeon, W., Lee, K., Kim, D., Kim, O-H., Choi, M., Lee, H-W., Kim, Y. & Cho, T-J., 7 Mar 2019, In : American Journal of Human Genetics. 104, 3, p. 439-453

Research output: Contribution to journal › Article

Biallelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes
Burrage, L., Reynolds, J., Baratang, N., Phillips, J., Wegner, J., McFarquhar, A., Higgs, M., Christiansen, A., Lanza, D., Seavitt, J., Jain, M., Li, X., Parry, D., Raman, V., Chitayat, D., Chinn, I., Bertuch, A., Karaviti, L., Schlesinger, A., Earl, D. & 39 others, Bamshad, M., Savarirayan, R., Doddapaneni, H., Muzny, D., Jhangiani, S., Eng, C., Gibbs, R., Bi, W., Emrick, L., Rosenfeld, J., Postlethwait, J., Westerfield, M., Dickinson, M., Beaudet, A., Ranza, E., Huber, C., Cormier-Daire, V., Shen, W., Mao, R., Heaney, J., Orange, J., Undiagnosed Diseases Network, Bertola, D., Yamamoto, G., Baratela, W., Butler, M., Ali, A., Adeli, M., Cohn, D., Krakow, D., Jackson, A., Lees, M., Offiah, A., Carlston, C., Carey, J., Grant Stewart, Bacino, C., Campeau, P. & Lee, B., 14 Feb 2019, In : American Journal of Human Genetics. 104, 3, p. 422-438

Research output: Contribution to journal › Article

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