Giovanni Bottegoni

Publications

  1. 2016
  2. Published

    Molecular Dynamics Simulations and Kinetic Measurements to Estimate and Predict Protein-Ligand Residence Times

    Giovanni Bottegoni, 11 Aug 2016, In : Journal of Medicinal Chemistry. 59, 15, p. 7167-7176 10 p.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Development and Application of a Virtual Screening Protocol for the Identification of Multitarget Fragments

    Giovanni Bottegoni, 20 Jun 2016, In : ChemMedChem. 11, 12, p. 1259-1263 5 p.

    Research output: Contribution to journalArticlepeer-review

  4. Published
  5. Published

    Role of Molecular Dynamics and Related Methods in Drug Discovery

    Giovanni Bottegoni, 12 May 2016, In : Journal of Medicinal Chemistry. 59, 9, p. 4035-4061 27 p.

    Research output: Contribution to journalReview articlepeer-review

  6. Published

    Diaryl urea: A privileged structure in anticancer agents

    Giovanni Bottegoni, 1 May 2016, In : Current medicinal chemistry. 23, 15, p. 1528-1548 21 p.

    Research output: Contribution to journalReview articlepeer-review

  7. Published
  8. Published

    Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors

    Giovanni Bottegoni, 28 Jan 2016, In : Journal of Medicinal Chemistry. 59, 2, p. 531-544 14 p.

    Research output: Contribution to journalArticlepeer-review

  9. 2015
  10. Published

    3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease

    Giovanni Bottegoni, 14 Jul 2015, In : ACS Chemical Neuroscience. 6, 10, p. 1665-1682 18 p.

    Research output: Contribution to journalArticlepeer-review

  11. Published

    Dual inhibition of REV-ERBβ and autophagy as a novel pharmacological approach to induce cytotoxicity in cancer cells

    Giovanni Bottegoni, 14 May 2015, In : Oncogene. 34, 20, p. 2597-2608 12 p.

    Research output: Contribution to journalArticlepeer-review

  12. Published

    Structure-based predictions of activity cliffs

    Giovanni Bottegoni, 28 Apr 2015, In : Journal of Chemical Information and Modeling. 55, 5, p. 1062-1076 15 p.

    Research output: Contribution to journalArticlepeer-review