Giovanni Bottegoni

Publications

  1. 2019
  2. Published

    Multi-Target Dopamine D3 Receptor Modulators: Actionable Knowledge for Drug Design from Molecular Dynamics and Machine Learning

    Ferraro, M., Decherchi, S., Simone, A. D., Recanatini, M., Cavalli, A. & Giovanni Bottegoni, 3 Jun 2019

    Research output: Other contribution

  3. Published

    A triazolotriazine-based dual GSK-3β/CK-1δ ligand as a potential neuroprotective agent presenting two different mechanisms of enzymatic inhibition

    Redenti, S., Marcovih, I., De Vita, T., Perez, C., De Zorzi, R., Demitri, N., Perez, D. I., Giovanni Bottegoni, Bisignano, P., Bissaro, M., Moro, S., Martinez, A., Storici, P., Spalluto, G., Cavalli, A. & Federico, S., 5 Feb 2019, In : ChemMedChem. 14, 3, p. 310-314 5 p.

    Research output: Contribution to journalArticle

  4. 2018
  5. Published

    BiKi Life Sciences: A New Suite for Molecular Dynamics and Related Methods in Drug Discovery

    Decherchi, S., Giovanni Bottegoni, Spitaleri, A., Rocchia, W. & Cavalli, A., 26 Feb 2018, In : Journal of Chemical Information and Modeling. 58, 2, p. 219-224 6 p.

    Research output: Contribution to journalArticle

  6. Published

    BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease

    Prati, F., Giovanni Bottegoni, Bolognesi, M. L. & Cavalli, A., 8 Feb 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 619-637 19 p.

    Research output: Contribution to journalReview article

  7. Published

    Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727

    Robertson, N., Rappas, M., Doré, A. S., Brown, J., Giovanni Bottegoni, Koglin, M., Cansfield, J., Jazayeri, A., Cooke, R. M. & Marshall, F. H., 3 Jan 2018, In : Nature. 553, p. 111-114 4 p.

    Research output: Contribution to journalArticle

  8. 2017
  9. Published

    Multitarget drug design strategy in Alzheimer's disease: Focus on cholinergic transmission and amyloid-β aggregation

    Simoni, E., Bartolini, M., Abu, I. F., Blockley, A., Gotti, C., Giovanni Bottegoni, Caporaso, R., Bergamini, C., Andrisano, V., Cavalli, A., Mellor, I. R., Minarini, A. & Rosini, M., 1 Jun 2017, In : Future Medicinal Chemistry. 9, 10, p. 953-963 11 p.

    Research output: Contribution to journalArticle

  10. Published

    Computational Methods in Multitarget Drug Discovery

    Giovanni Bottegoni & Cavalli, A., 11 Apr 2017, Design of Hybrid Molecules for Drug Development. Elsevier, p. 239-258 20 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  11. Published

    Design, Synthesis, Structure-Activity Relationship Studies, and Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) Modeling of a Series of O-Biphenyl Carbamates as Dual Modulators of Dopamine D3 Receptor and Fatty Acid Amide Hydrolase

    De Simone, A., Russo, D., Ruda, G. F., Micoli, A., Ferraro, M., Di Martino, R. M. C., Ottonello, G., Summa, M., Armirotti, A., Bandiera, T., Cavalli, A. & Giovanni Bottegoni, 23 Mar 2017, In : Journal of Medicinal Chemistry. 60, 6, p. 2287-2304 18 p.

    Research output: Contribution to journalArticle

  12. 2016
  13. Published

    Mapping cholesterol interaction sites on serotonin transporter through coarse-grained molecular dynamics

    Ferraro, M., Masetti, M., Recanatini, M., Cavalli, A. & Giovanni Bottegoni, 1 Dec 2016, In : PLoS ONE. 11, 12, e0166196.

    Research output: Contribution to journalArticle

  14. Published

    Pyrazole-Based Acid Ceramidase Inhibitors: Design, Synthesis, and Structure-Activity Relationships

    Diamanti, E., Giovanni Bottegoni, Goldoni, L., Realini, N., Pagliuca, C., Bertozzi, F., Piomelli, D. & Pizzirani, D., 1 Sep 2016, In : Synthesis (Germany). 48, 17, p. 2739-2756 18 p.

    Research output: Contribution to journalArticle

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