Gary Middleton

Colleges, School and Institutes

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Most downloaded publications

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
& 31 others, , Gary Middleton, 25 May 2017, In : Nature. 545, 7655, p. 446-451 6 p.

Research output: Contribution to journal › Article

361 downloads
Tracking the Evolution of Non-Small-Cell Lung Cancer
& 63 others, , Babu Naidu, Gary Middleton, 1 Jun 2017, In : New England Journal of Medicine. 376, 22, p. 2109-2121

Research output: Contribution to journal › Article

332 downloads
An immunogenomic stratification of colorectal cancer : implications for development of targeted immunotherapy
Andrew Beggs, Benjamin Willcox & Gary Middleton, 2 Apr 2015, In : OncoImmunology. 4, 3, e976052.

Research output: Contribution to journal › Article

258 downloads
Immunobiological effects of gemcitabine and capecitabine combination chemotherapy in advanced pancreatic ductal adenocarcinoma
Gary Middleton, 4 Feb 2016, In : British Journal of Cancer.

Research output: Contribution to journal › Article

255 downloads
The National Lung Matrix Trial : translating the biology of stratification in advanced non-small-cell lung cancer
Gary Middleton & Cindy Billingham, 12 Dec 2015, In : Annals of Oncology. 26, 12, p. 2464-2469

Research output: Contribution to journal › Article

163 downloads

Recent publications

Pembrolizumab in patients with non-small-cell lung cancer of performance status 2 (PePS2): a single arm, phase 2 trial
Gary Middleton, Kristian Brock & Cindy Billingham, 19 Mar 2020, In : The Lancet Respiratory Medicine.

Research output: Contribution to journal › Article

A phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol
Anthony Kong, Amanda Kirkham, Jo Parish, Rachel Spruce, Gary Middleton, Christina Yap & Hisham Mehanna, 16 Mar 2020, In : BMJ open. 10, 3, e033009.

Research output: Contribution to journal › Article

BRAF-mutant transcriptional subtypes predict outcome of combined BRAF, MEK, and EGFR blockade with dabrafenib, trametinib, and panitumumab in patients with colorectal cancer
Gary Middleton & 2 others, , 11 Feb 2020, In : Clinical Cancer Research.

Research output: Contribution to journal › Article

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Recent Activities

A Phase II Clinical Trial with Efficacy and Toxicity Outcomes and Baseline Covariates
Kristian Brock (Speaker), Cindy Billingham (Contributor), Gary Middleton (Contributor), Christina Yap (Contributor)
2 Jul 2018

Activity: Talk or presentation › Academic conference

Design dilemmas in the multi-drug, genetic-marker-directed, non-comparative, multi-centre, multi-arm phase II National Lung Matrix Trial
Cindy Billingham (Invited speaker), (Invited speaker), Kristian Brock (Invited speaker), (Invited speaker), Gary Middleton (Invited speaker)
26 Aug 2014

Activity: Talk or presentation › Academic conference

View all (2)