Gary Middleton

Colleges, School and Institutes

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Most downloaded publications

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
& 31 others, , Gary Middleton, 25 May 2017, In : Nature. 545, 7655, p. 446-451 6 p.

Research output: Contribution to journal › Article

296 downloads
Tracking the Evolution of Non-Small-Cell Lung Cancer
& 63 others, , Babu Naidu, Gary Middleton, 1 Jun 2017, In : New England Journal of Medicine. 376, 22, p. 2109-2121

Research output: Contribution to journal › Article

279 downloads
An immunogenomic stratification of colorectal cancer : implications for development of targeted immunotherapy
Andrew Beggs, Benjamin Willcox & Gary Middleton, 2 Apr 2015, In : OncoImmunology. 4, 3, e976052.

Research output: Contribution to journal › Article

234 downloads
The National Lung Matrix Trial : translating the biology of stratification in advanced non-small-cell lung cancer
Gary Middleton & Cindy Billingham, 12 Dec 2015, In : Annals of Oncology. 26, 12, p. 2464-2469

Research output: Contribution to journal › Article

147 downloads
KRAS mutation and Consensus Molecular Subtypes 2 and 3 are independently associated with reduced immune infiltration and reactivity in colorectal cancer
Neeraj Lal, Oliver Pickles, Andrew Beggs, Benjamin Willcox & Gary Middleton, 23 Oct 2017, In : Clinical Cancer Research.

Research output: Contribution to journal › Article

92 downloads

Recent publications

The role of B lymphocytes in the immuno-biology of non-small-cell lung cancer
Akshay Patel, Alex Richter, Mark Drayson & Gary Middleton, 4 Jan 2020, In : Cancer Immunology Immunotherapy.

Research output: Contribution to journal › Article

Development and validation of a combined hypoxia and immune prognostic classifier for head and neck cancer: hypoxia-immune prognostic classifier for HNC
Jill Brooks, Albert Menezes Antao Nobre De Menezes, Lucinda Archer, Neeraj Lal, Rachel Spruce, Nikos Batis, Jennifer Bryant, Gordon Ryan, Steve Lee, Gary Middleton, Daniel Tennant & 7 others, Andrew Beggs, Jon Deeks, Jean-Baptiste Cazier, Benjamin Willcox & Hisham Mehanna, 1 Sep 2019, In : Clinical Cancer Research. 25, 17, p. 5315-5328 15 p.

Research output: Contribution to journal › Article

MDSC targeting with Gemtuzumab ozogamicin restores T cell immunity and immunotherapy against cancers
Paul Collins, Suzanne Graef, Sarah Booth, Boris Noyvert, Claire Shannon-Lowe, Gary Middleton, Francis Mussai & Carmela De Santo, 1 Sep 2019, In : EBioMedicine. 47, p. 235-246 12 p.

Research output: Contribution to journal › Article

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Recent Activities

A Phase II Clinical Trial with Efficacy and Toxicity Outcomes and Baseline Covariates
Kristian Brock (Speaker), Cindy Billingham (Contributor), Gary Middleton (Contributor), Christina Yap (Contributor)
2 Jul 2018

Activity: Talk or presentation › Academic conference

Design dilemmas in the multi-drug, genetic-marker-directed, non-comparative, multi-centre, multi-arm phase II National Lung Matrix Trial
Cindy Billingham (Invited speaker), (Invited speaker), Kristian Brock (Invited speaker), (Invited speaker), Gary Middleton (Invited speaker)
26 Aug 2014

Activity: Talk or presentation › Academic conference

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