Derek Kyte

Colleges, School and Institutes

Biography

Dr Kyte completed his BSc in Physiotherapy in 1996. He worked as a Specialist Musculoskeletal Physiotherapist in the NHS for 11 years, before taking up a post as a Clinical Tutor at the University of Birmingham in 2007. He gained an MSc at the University in 2009, went on to complete his PhD in 2015, and took up his current post as a HEFCE-funded Lecturer in Health Research Methods in 2015. In 2017, Dr Kyte was awarded a highly prestigious NIHR post-doctoral fellowship and received the University of Birmingham Founders’ Award for Outstanding Early-Career Academic. 

Research interests

Derek Kyte, PhD, is a Lecturer in Health Research Methods at the University of Birmingham UK and NIHR Fellow. He has extensive experience in applied health research methods including trials methodology, systematic reviews, meta-analysis, epidemiology and mixed-methods. His primary research interests surround health outcomes, including the best-practice use of patient-reported outcome (PRO) assessment in clinical trials and routine practice. Dr Kyte is chief investigator of the RePROM trial, investigating the use of online PRO symptom monitoring to support the routine care of patients with advanced chronic kidney disease.

Dr Kyte is a member of the Centre for PROs Research www.birmingham.ac.uk/cpror which aims to optimize the use of PROs in clinical trials and routine care, to improve service delivery, enhance patient care and outcomes and ensure that the patient perspective is at the heart of health research and NHS decision-making. He has a current total grant income in excess of £3 million and has contributed to the cross-cutting PROs research themes within major UoB NIHR infrastructure including the Biomedical Research Centre, Surgical Reconstruction and Microbiology Research Centre, Clinical Research Facility (awards >£25 million) and the Institute for Translational Medicine.  

 

Dr Kyte has 50 peer reviewed publications in journals including the BMJ, JAMA, PLOS Medicine, Lancet Oncology, JNCI and the Lancet, with a H-index of 14 (i10-index 20). His highly-cited work has informed the recent European Medicines Agencies guidelines on the evaluation of anticancer medicinal products in man and is REF returnable. His work has included publications on PRO research guidelines (JAMA); research impact (PLOS Medicine); observational research (BMJ); the conduct of PRO assessment within trials (JNCI, PLOS One, JPRO, Qual Life Res, Lancet commentary, Expert Review of Pharmacoeconomics & Outcomes Research);issues surrounding ‘PRO Alerts’ (JAMA viewpoint, PLOS One, BMJ Open); PROs in Big data and NHS benchmarking (JRSM); and PROs in routine clinical practice (the BMJ, American Journal of Kidney Diseases, BMJ Open, Curr Opin Nephrol Hypertens, Br J Ophthalmol, Eye Journal). Dr Kyte’s research has featured in the prestigious PLOS Progress update 2014/2015, an annual summary of innovations and journal highlights. 

Dr Kyte is a member of the International Society for Quality of Life Research (ISOQOL) and the ‘Best Practices for PROs in Randomised Clinical Trials’ and SPIRIT PRO Extension ISOQOL Taskforce initiatives. He also chairs the UK National Cancer Research Institute (NCRI) Psychosocial Oncology and Survivorship CSG subgroup: ‘Understanding and measuring the consequences of cancer and its treatment’. 

Willingness to take PhD students

Yes

PhD projects

My primary research interests surround health outcomes, including the best-practice use of PRO (patient-reported outcomes) and PROM (patient-reported outcome measure) assessment in clinical trials and routine clinical practice:

- I have a keen interest in investigating the use of online PRO symptom monitoring to support the routine care of patients in the NHS - in particular, within chronic kidney disease.

- In my role as an advisor within the National Cancer Research Institute, I am also interested in exploring ways to optimise PRO capture in cancer settings.