Conny Bonifer

Publications

  1. Published

    A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program

    Anetta Ptasinska, , , Salam Assi, Paulynn Suyin Chin, Maria Imperato, , , , Conny Bonifer & , 7 Sep 2017, In: Blood. 130, 10, p. 1213-1222 10 p.

    Research output: Contribution to journalArticlepeer-review

  2. Published

    A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification

    Jane Gilmour, Salam Assi, , , , , , & Conny Bonifer, Jun 2014, In: Development (Cambridge). 141, 12, p. 2391-2401

    Research output: Contribution to journalArticlepeer-review

  3. Published
  4. Published

    A highly conserved c-fms gene intronic element controls macrophage-specific and regulated expression

    Conny Bonifer & , 1 Nov 2001, In: Journal of Leukocyte Biology. 70, 5, p. 812-820 9 p.

    Research output: Contribution to journalArticlepeer-review

  5. Published
  6. Published

    Aberrant expression of CD19 in AML with t(8;21) involves a poised chromatin structure and PAX5

    Peter Cockerill, , , Maarten Hoogenkamp, , , , Conny Bonifer & , 20 May 2010, In: Oncogene. 29, 20, p. 2927-37 11 p.

    Research output: Contribution to journalArticle

  7. Published

    Aberrant transcriptional programming in blood cancers

    Conny Bonifer, Peter Cockerill & Anetta Ptasinska, 2015, Chromosomal Translocations and Genome Rearrangements in Cancer. Rowley, J., Le Beau, M. & Rabbitts, T. H. (eds.).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  8. Published

    An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression

    Conny Bonifer, & , 1 Sep 2010, In: Nucleic Acids Research. 38, 16, p. 5336-50 15 p.

    Research output: Contribution to journalArticle

  9. Published

    An in vitro Differentiation System for the Examination of Transgene Activation in Mouse Macrophages

    Conny Bonifer, & , 1994, In: DNA and Cell Biology. 13, 9, p. 901-907

    Research output: Contribution to journalArticlepeer-review

  10. Published
  11. Published

    Analyzing histone modification using crosslinked chromatin treated with micrococcal nuclease

    Conny Bonifer, 1 Jan 2006, In: Methods in molecular biology. 325, p. 315-25 11 p.

    Research output: Contribution to journalArticle

  12. Published

    C/EBP beta induces chromatin opening at a cell-type-specific enhancer

    Conny Bonifer & , 1 Mar 2008, In: Molecular and Cellular Biology. 28, 6, p. 2102-2112 11 p.

    Research output: Contribution to journalArticle

  13. Published

    C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis

    Maarten Hoogenkamp, , , , , , , , Conny Bonifer & , 11 Aug 2015, In: Stem Cell Reports. 5, 2, p. 232-247

    Research output: Contribution to journalArticlepeer-review

  14. Published
  15. Published

    Characterization of RNA aptamers that disrupt the RUNX1-CBFbeta/DNA complex

    Conny Bonifer & , 1 Nov 2009, In: Nucleic Acids Research. 37, 20, p. 6818-30 13 p.

    Research output: Contribution to journalArticle

  16. Published
  17. Published

    Chromatin Structure Profiling Identifies Crucial Regulators of Tumor Maintenance

    Conny Bonifer & Peter Cockerill, 1 Nov 2015, In: Trends in Cancer. 1, 3, p. 157-160 4 p.

    Research output: Contribution to journalShort surveypeer-review

  18. Published
  19. Published

    Chromatin mechanisms regulating gene expression in health and disease

    Conny Bonifer & Peter Cockerill, 1 Jan 2011, In: Advances in Experimental Medicine and Biology. 711, p. 12-25 14 p.

    Research output: Contribution to journalReview article

  20. Published

    Chromatin priming of genes in development: concepts, mechanisms and consequences

    Conny Bonifer & Peter Cockerill, May 2017, In: Experimental Hematology. 49, p. 1-8

    Research output: Contribution to journalReview articlepeer-review

  21. E-pub ahead of print
  22. Published

    Chromatin regulation by RUNX1

    Monika Lichtinger, Maarten Hoogenkamp, , & Conny Bonifer, 15 Apr 2010, In: Blood Cells, Molecules & Diseases. 44, 4, p. 287-90 4 p.

    Research output: Contribution to journalArticle

  23. Published
  24. Published
  25. Published
  26. Published

    Control of expression of the chicken lysozyme gene and its potential application in transgenic birds

    Conny Bonifer, 1994, Genetics Applied in Livestock Production . Burnside, E. B. (ed.). Vol. 21. p. 307-313

    Research output: Chapter in Book/Report/Conference proceedingChapter

  27. Published
  28. Published
  29. Published

    Cyclooxigenase-2 is upregulated and localized to macrophages in the intestine of min mice

    Conny Bonifer, & , Mar 1999, In: British Journal of Cancer. 79, 9/10, p. 1399-1405

    Research output: Contribution to journalArticlepeer-review

  30. Published

    Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: Its more than NF-κB!

    Pierre Cauchy, Conny Bonifer & , Mar 2015, In: Cytokine. 72, 1, p. 115–117

    Research output: Contribution to journalArticle

  31. Published

    Delineating MEIS1 cis-regulatory elements active in hematopoietic cells

    Conny Bonifer, Peter Cockerill, , , & , Feb 2014, In: Leukemia. 28, 2, p. 433-436 4 p.

    Research output: Contribution to journalLetterpeer-review

  32. Published
  33. Published

    Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma

    & 5 others, Peter Cockerill, , , Conny Bonifer & , 1 May 2010, In: Nature Medicine. 16, 5, p. 571-9, 1p following 579

    Research output: Contribution to journalArticlepeer-review

  34. Published

    Determination of DNA-Elements Necessary for Macrophage Specific and Position Independent Expression of the Chicken Lysozyme Gene in Transgenic Mice

    Conny Bonifer, , & , 1991, Human Gene Transfer. INSERM, p. 267-269 (Colloques Inserm; vol. 219).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  35. Published
  36. Published

    Developmental changes in the differentiation capacity of hematopoietic stem cells

    Conny Bonifer, , & , 1 May 1998, In: Immunology Today. 19, 5, p. 236-241

    Research output: Contribution to journalArticlepeer-review

  37. Published

    Developmental regulation of eukaryotic gene loci: which cis-regulatory information is required?

    Conny Bonifer, 1 Jul 2000, In: Trends in Genetics. 16, 7, p. 310-315

    Research output: Contribution to journalArticlepeer-review

  38. Published

    Developmental-stage-dependent transcriptional response to leukaemic oncogene expression

    Salam Assi, , Jane Gilmour, & Conny Bonifer, 28 May 2015, In: Nature Communications. 6, 7203.

    Research output: Contribution to journalArticlepeer-review

  39. Published
  40. Published
  41. Published
  42. Published

    Different macrophage populations develop from embryonic/fetal and adult hematopoietic tissues

    Conny Bonifer, 1997, In: Experimental Hematology. 25, 5, p. 432-444

    Research output: Contribution to journalArticlepeer-review

  43. Published
  44. Published
  45. Published
  46. Published
  47. Published

    Dissecting Clonal Heterogeneity in AML

    Conny Bonifer, 14 Dec 2020, In: Cancer Cell. 38, 6, p. 782-784 3 p.

    Research output: Contribution to journalArticle

  48. Published

    Dissection of the Locus Control Function located on the Chicken Lysozyme Gene Domain

    Conny Bonifer, , , & , 11 Oct 1994, In: Nucleic Acids Research. 22, 20, p. 4202-4210

    Research output: Contribution to journalArticlepeer-review

  49. Published
  50. Published

    Dynamic Chromatin: The Regulatory Domain Organization of Eucaryotic Gene Loci

    Conny Bonifer, , , & , 1991, In: Journal of Cellular Biochemistry. 47, p. 99-108

    Research output: Contribution to journalArticlepeer-review

  51. Published
  52. Published
  53. Published
  54. Published

    Epigenetic consequences of AML1-ETO action at the human c-FMS locus

    Conny Bonifer, 2 Jun 2003, In: The EMBO journal. 22, 11, p. 2798-809 12 p.

    Research output: Contribution to journalArticle

  55. Published
  56. Published

    Epigenetic plasticity of hematopoietic cells

    Conny Bonifer, 1 Feb 2005, In: Cell Cycle. 4, 2, p. 211-4 4 p.

    Research output: Contribution to journalArticle

  57. Published

    Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible

    Conny Bonifer, 27 Oct 2004, In: The EMBO journal. 23, 21, p. 4275-85 11 p.

    Research output: Contribution to journalArticle

  58. Published
  59. Published

    Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

    Peter Keane, , , & Conny Bonifer, 26 May 2020, In: Cell Reports. 31, 8, 107691.

    Research output: Contribution to journalArticlepeer-review

  60. Published

    Expression of the Glucocorticoid Receptor in E.coli

    Conny Bonifer, , , , & , Sep 1988, Steroid Hormone Action: (UCLA Symposia on Molecular and Cellular Biology, New Series). Ringold, G. (ed.). New York: Alan R Liss Inc, p. 201-209

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  61. Published
  62. Published

    GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment

    Monika Lichtinger, , , , , Conny Bonifer, , & , 2012, In: Blood. 120, 2, p. 314-22 9 p.

    Research output: Contribution to journalArticlepeer-review

  63. Published
  64. Published
  65. Published

    Globin gene expression is reprogrammed in chimeras generated by injecting adult hematopoietic stem cells into mouse blastocysts

    Conny Bonifer & , 12 Jun 1998, In: Cell. 93, 6, p. 1055-1065

    Research output: Contribution to journalArticlepeer-review

  66. Published
  67. Published
  68. Published

    Identification and Characterization of the Protein Encoded by the Human c-myb Protooncogene

    Conny Bonifer & , 1986, In: EMBO Journal. 5, 8, p. 1903-1911

    Research output: Contribution to journalArticlepeer-review

  69. Published
  70. Published

    Identification of cis-acting elements as DNase I hypersensitive sites in lysozyme gene chromatin

    Conny Bonifer, 1996, In: Methods in Enzymology. 557, p. 233-246

    Research output: Contribution to journalArticlepeer-review

  71. Published
  72. Published
  73. Published
  74. Published
  75. Published

    In vivo genomic footprinting using LM-PCR methods

    Peter Cockerill & Conny Bonifer, 1 Jan 2006, In: Methods in molecular biology. 325, p. 285-314 30 p.

    Research output: Contribution to journalArticle

  76. Published

    Inducible chromatin priming is associated with the establishment of immunological memory in T cells

    Sarah Bevington, Pierre Cauchy, , , , , Niall Gilding, , Conny Bonifer & Peter Cockerill, Mar 2016, In: The EMBO journal. 35, 5, p. 515-535 21 p.

    Research output: Contribution to journalArticlepeer-review

  77. Published

    Instructive role of MLL-fusion proteins revealed by a model of t(4;11) pro-B acute lymphoblastic leukemia

    Anetta Ptasinska, , Salam Assi, , , , , , , , , , Conny Bonifer, & , 14 Nov 2016, In: Cancer Cell. 30, 5, p. 737–749 13 p.

    Research output: Contribution to journalArticlepeer-review

  78. Published

    Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1

    Salam Assi, Paulynn Suyin Chin, Daniel Coleman, Anna Pickin, , , , Peter Cockerill & Conny Bonifer, 20 Apr 2021, In: Cell Reports. 35, 3, 26 p., 109010.

    Research output: Contribution to journalArticlepeer-review

  79. Published
  80. Published

    Lack of inducible nitric Oxidase Synthase promotes intestinal tunorigenesis in the APC(min/+) mouse

    Conny Bonifer & , Oct 2001, In: Gastroenterology. 121, 4, p. 889-899 11 p.

    Research output: Contribution to journalArticlepeer-review

  81. Published
  82. Published

    Localisation of cyclooxygenase-2 in sporadic colorectal adenomas

    Conny Bonifer, , , , , & , Feb 2000, In: The American Journal of Pathology. 156, 2, p. 545–553

    Research output: Contribution to journalArticlepeer-review

  83. Published

    Long range chromatin mechanisms regulating gene locus activation

    Conny Bonifer, 1 Oct 1999, In: Gene. 238, 2, p. 277-289

    Research output: Contribution to journalArticlepeer-review

  84. Published

    Lymphodepletion in the ApcMin/+ mouse model of intestinal tumorigenesis

    Conny Bonifer & , 1 Feb 2004, In: Blood. 103, 3, p. 1050-8 9 p.

    Research output: Contribution to journalArticlepeer-review

  85. Published

    Macrophage development from HSCs requires PU.1-coordinated microRNA expression

    Maarten Hoogenkamp, , , Conny Bonifer, , , & , 25 Aug 2011, In: Blood. 118, 8, p. 2275-2284 10 p.

    Research output: Contribution to journalArticlepeer-review

  86. Published
  87. Published

    Modelling t(8;21) acute myeloid leukaemia ‐ What have we learned?

    Paulynn Suyin Chin & Conny Bonifer, 24 Sep 2020, In: MedComm.

    Research output: Contribution to journalArticlepeer-review

  88. E-pub ahead of print
  89. Published
  90. Published
  91. Published
  92. Published
  93. Published

    Polynucleotides for Use in Medicine

    Conny Bonifer, 2015, IPC No. European patent application, Patent No. 10735185.0

    Research output: Patent

  94. Published

    Prerequisites for Tissue Specific and Position Independent Expression of a Gene Locus in Transgenic Mice

    Conny Bonifer, , , & , Nov 1996, In: Journal of Molecular Medicine. 74, 11, p. 663-671

    Research output: Contribution to journalArticlepeer-review

  95. Published

    Prospective isolation and characterization of genetically and functionally distinct AML subclones

    Peter Keane, Maria Imperato, , , , , , , , , , Peter Cockerill, , , , Conny Bonifer & , 8 Oct 2018, In: Cancer Cell. 34, 4, p. 674-689.e8 24 p.

    Research output: Contribution to journalArticlepeer-review

  96. Published
  97. Published

    RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence

    Conny Bonifer, , & , 11 Sep 2014, In: Blood. 124, 11, p. e11-e20

    Research output: Contribution to journalArticlepeer-review

  98. Published

    RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element

    Conny Bonifer, , & , 1 Oct 2011, In: The EMBO journal. 30, 19, p. 4059-4070 12 p.

    Research output: Contribution to journalArticle

  99. Published

    RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

    Monika Lichtinger, , , , , , , , , , , , , , & Conny Bonifer, 14 Nov 2012, In: The EMBO journal. 31, 22, p. 4318-4333 16 p.

    Research output: Contribution to journalArticlepeer-review

  100. Published
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