Conny Bonifer

Publications

  1. 2011
  2. Published

    RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element

    Conny Bonifer, , & , 1 Oct 2011, In: The EMBO journal. 30, 19, p. 4059-4070 12 p.

    Research output: Contribution to journalArticle

  3. 2012
  4. Published

    GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment

    Monika Lichtinger, , , , , Conny Bonifer, , & , 2012, In: Blood. 120, 2, p. 314-22 9 p.

    Research output: Contribution to journalArticlepeer-review

  5. Published
  6. Published
  7. Published

    RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

    Monika Lichtinger, , , , , , , , , , , , , , & Conny Bonifer, 14 Nov 2012, In: The EMBO journal. 31, 22, p. 4318-4333 16 p.

    Research output: Contribution to journalArticlepeer-review

  8. 2013
  9. Published

    The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus

    Conny Bonifer & , 2013, In: PLoS ONE. 8, 1, p. e54935

    Research output: Contribution to journalArticlepeer-review

  10. Published
  11. Published
  12. Published

    Why detailed model gene studies in higher eukaryotes are still necessary

    Conny Bonifer, Jun 2013, In: Immunology. 139, 2, p. 158-60 3 p.

    Research output: Contribution to journalArticlepeer-review

  13. Published
  14. Published
  15. Published
  16. Published

    Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia

    Maarten Hoogenkamp, Conny Bonifer & 2 others, & , 11 Nov 2013, In: Cancer Cell. 24, 5, p. 575-588 14 p.

    Research output: Contribution to journalArticlepeer-review

  17. 2014
  18. Published
  19. Published

    Delineating MEIS1 cis-regulatory elements active in hematopoietic cells

    Conny Bonifer, Peter Cockerill, , , & , Feb 2014, In: Leukemia. 28, 2, p. 433-436 4 p.

    Research output: Contribution to journalLetterpeer-review

  20. Published

    A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification

    Jane Gilmour, Salam Assi, , , , , , & Conny Bonifer, Jun 2014, In: Development (Cambridge). 141, 12, p. 2391-2401

    Research output: Contribution to journalArticlepeer-review

  21. Published

    RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence

    Conny Bonifer, , & , 11 Sep 2014, In: Blood. 124, 11, p. e11-e20

    Research output: Contribution to journalArticlepeer-review

  22. Published
  23. Published
  24. 2015
  25. Published

    Aberrant transcriptional programming in blood cancers

    Conny Bonifer, Peter Cockerill & Anetta Ptasinska, 2015, Chromosomal Translocations and Genome Rearrangements in Cancer. Rowley, J., Le Beau, M. & Rabbitts, T. H. (eds.).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  26. Published

    Polynucleotides for Use in Medicine

    Conny Bonifer, 2015, IPC No. European patent application, Patent No. 10735185.0

    Research output: Patent

  27. Published

    RUNX1/ETO blocks selectin-mediated adhesion via epigenetic silencing of PSGL-1

    Anetta Ptasinska, Salam Assi, , , , Conny Bonifer, & , 2015, In: Oncogenesis. 4, e146.

    Research output: Contribution to journalArticlepeer-review

  28. Published

    Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: Its more than NF-κB!

    Pierre Cauchy, Conny Bonifer & , Mar 2015, In: Cytokine. 72, 1, p. 115–117

    Research output: Contribution to journalArticle

  29. Published

    The RUNX1-PU.1 axis in the control of hematopoiesis

    Maria Imperato, Pierre Cauchy, Nadine Obier & Conny Bonifer, Apr 2015, In: International journal of hematology. 101, 4, p. 319-329

    Research output: Contribution to journalArticlepeer-review

  30. Published

    Developmental-stage-dependent transcriptional response to leukaemic oncogene expression

    Salam Assi, , Jane Gilmour, & Conny Bonifer, 28 May 2015, In: Nature Communications. 6, 7203.

    Research output: Contribution to journalArticlepeer-review

  31. Published
  32. Published

    C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis

    Maarten Hoogenkamp, , , , , , , , Conny Bonifer & , 11 Aug 2015, In: Stem Cell Reports. 5, 2, p. 232-247

    Research output: Contribution to journalArticlepeer-review

  33. Published

    Chromatin Structure Profiling Identifies Crucial Regulators of Tumor Maintenance

    Conny Bonifer & Peter Cockerill, 1 Nov 2015, In: Trends in Cancer. 1, 3, p. 157-160 4 p.

    Research output: Contribution to journalShort surveypeer-review

  34. Published
  35. E-pub ahead of print

    UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO

    Salam Assi, Anetta Ptasinska, , Conny Bonifer, , & , 1 Dec 2015, (E-pub ahead of print) In: Leukemia.

    Research output: Contribution to journalArticlepeer-review

  36. 2016
  37. Published
  38. Published

    The leukemia-associated RUNX1/ETO oncoprotein confers a mutator phenotype

    Anetta Ptasinska, Salam Assi, , , Conny Bonifer, & Jeffery Allan, Jan 2016, In: Leukemia. 30

    Research output: Contribution to journalArticlepeer-review

  39. E-pub ahead of print
  40. Published

    Inducible chromatin priming is associated with the establishment of immunological memory in T cells

    Sarah Bevington, Pierre Cauchy, , , , , Niall Gilding, , Conny Bonifer & Peter Cockerill, Mar 2016, In: The EMBO journal. 35, 5, p. 515-535 21 p.

    Research output: Contribution to journalArticlepeer-review

  41. Published
  42. Published

    Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers

    Jane Gilmour, Anna Pickin & 3 others, , Conny Bonifer & , Jun 2016, In: EBioMedicine. 8, June 2016, p. 117-131

    Research output: Contribution to journalArticlepeer-review

  43. E-pub ahead of print
  44. Published

    Instructive role of MLL-fusion proteins revealed by a model of t(4;11) pro-B acute lymphoblastic leukemia

    Anetta Ptasinska, , Salam Assi, , , , , , , , , , Conny Bonifer, & , 14 Nov 2016, In: Cancer Cell. 30, 5, p. 737–749 13 p.

    Research output: Contribution to journalArticlepeer-review

  45. E-pub ahead of print

    The Role of the Ubiquitously Expressed Transcription Factor Sp1 in Tissue-specific Transcriptional Regulation and in Disease

    Jane Gilmour & Conny Bonifer, 23 Dec 2016, (E-pub ahead of print) In: Yale Journal of Biology and Medicine. 89, 4, p. 513-525

    Research output: Contribution to journalArticlepeer-review

  46. 2017
  47. Published

    Runx1 Structure and Function in Blood Cell Development

    Conny Bonifer, , & , 16 Mar 2017, RUNX Proteins in Development and Cancer. Groner, Y., Ito, Y., Liu, P., Neil, J. C., Speck, N. A. & van Wijnen, A. (eds.). Springer, p. 65-81 17 p. (Advances in Experimental Medicine and Biology; vol. 962, no. Book Part III).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  48. Published

    Chromatin priming of genes in development: concepts, mechanisms and consequences

    Conny Bonifer & Peter Cockerill, May 2017, In: Experimental Hematology. 49, p. 1-8

    Research output: Contribution to journalReview articlepeer-review

  49. Published
  50. Published

    A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program

    Anetta Ptasinska, , , Salam Assi, Paulynn Suyin Chin, Maria Imperato, , , , Conny Bonifer & , 7 Sep 2017, In: Blood. 130, 10, p. 1213-1222 10 p.

    Research output: Contribution to journalArticlepeer-review

  51. Published
  52. 2018
  53. Published
  54. Published
  55. Published
  56. Published

    Prospective isolation and characterization of genetically and functionally distinct AML subclones

    Peter Keane, Maria Imperato, , , , , , , , , , Peter Cockerill, , , , Conny Bonifer & , 8 Oct 2018, In: Cancer Cell. 34, 4, p. 674-689.e8 24 p.

    Research output: Contribution to journalArticlepeer-review

  57. Published
  58. Published
  59. 2019
  60. Published
  61. Published
  62. Published

    Rewiring of the transcription factor network in acute myeloid leukemia

    Salam Assi, Conny Bonifer & Peter Cockerill, 25 Jun 2019, In: Cancer Informatics. 18

    Research output: Contribution to journalComment/debatepeer-review

  63. Published
  64. Published

    Standing at odds: mutated RAS and hematopoietic stem cells

    Conny Bonifer, Nov 2019, In: Haematologica. 104, 11, p. 2125-2128 4 p.

    Research output: Contribution to journalArticle

  65. Published
  66. 2020
  67. Published
  68. Published

    Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

    Peter Keane, , , & Conny Bonifer, 26 May 2020, In: Cell Reports. 31, 8, 107691.

    Research output: Contribution to journalArticlepeer-review

  69. Published

    Modelling t(8;21) acute myeloid leukaemia ‐ What have we learned?

    Paulynn Suyin Chin & Conny Bonifer, 24 Sep 2020, In: MedComm.

    Research output: Contribution to journalArticlepeer-review

  70. Published
  71. E-pub ahead of print
  72. Published
  73. Published

    Dissecting Clonal Heterogeneity in AML

    Conny Bonifer, 14 Dec 2020, In: Cancer Cell. 38, 6, p. 782-784 3 p.

    Research output: Contribution to journalArticle

  74. 2021
  75. Published

    RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia

    Salam Assi, , Conny Bonifer & , 22 Jan 2021, In: Nature Communications. 12, 1, 520.

    Research output: Contribution to journalArticlepeer-review

  76. E-pub ahead of print

    The transcriptional regulation of normal and malignant blood cell development

    Conny Bonifer, 29 Jan 2021, (E-pub ahead of print) In: The FEBS journal.

    Research output: Contribution to journalReview articlepeer-review

  77. Published
  78. Published

    Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1

    Salam Assi, Paulynn Suyin Chin, Daniel Coleman, Anna Pickin, , , , Peter Cockerill & Conny Bonifer, 20 Apr 2021, In: Cell Reports. 35, 3, 26 p., 109010.

    Research output: Contribution to journalArticlepeer-review

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