Christopher McCabe

Colleges, School and Institutes

External positions

, SOCIETY FOR ENDOCRINOLOGY

20152019

THE WELLCOME TRUST

20132017

SOCIETY FOR ENDOCRINOLOGY

20112015

Qualifications

University
of Sheffield 1987-1990

BSc: First Class Special Honours in

Genetics

 

PhD: Genetic Aspects of Circadian Rhythmicity in Drosophila melanogaster

University of Birmingham 1990-1994

 

Professional Qualifications

  • PhD: Genetic Aspects of Circadian Rhythmicity in Drosophila melanogaster,

    1990 - 1994
  • BSc: First Class Special Honours in Genetics,

    1987 - 1990

Willingness to take PhD students

Yes

PhD projects

Chris McCabe works on mechanisms of endocrine cancers, including thyroid and breast tumour models. The McCabe group currently holds funding from the Wellcome Trust, the Medical Research Council and Cancer Research UK. Its current research focuses on:

Assessment of the role of the proto-oncogenes PTTG and PBF in thyroid, breast and colon tumours
In vitro and in vivo models exploring gene function
Gene expression in multiple tumour models
Mechanisms of aneuploidy and genetic instability in thyroid and colon cancer
The action of the sodium iodide symporter NIS in radioiodine treatment of thyroid and other tumours
Diverse mechanisms of endocrine cancer
Murine models of tumourigenesis

Professor McCabe currently supervises six doctoral researchers and is interested in supervising future projects in the areas of breast cancer invasion and thyroid cancer therapy.