Christina Yap

ORCID: 0000-0002-6715-2514

Colleges, School and Institutes

Willingness to take PhD students

Yes

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Most downloaded publications

A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma
Christina Yap, Ceri Oldreive, Daniel Slade, Paul Moss & Tatjana Stankovic, Aug 2018, In : British Journal of Haematology. 182, 3, p. 429-433

Research output: Contribution to journal › Letter

160 downloads
Adaptive designs in clinical trials: why use them, and how to run and report them
Christina Yap, 28 Feb 2018, In : BMC medicine. 16, 1, 29.

Research output: Contribution to journal › Article

145 downloads
Embracing model-based designs for dose-finding trials
Christina Yap & Charles Craddock, 25 Jul 2017, In : British Journal of Cancer. 117, 3, p. 332-339 8 p.

Research output: Contribution to journal › Article

130 downloads
How to design a dose-finding study using the continual reassessment method
Kristian Brock, Christina Yap, 18 Jan 2019, In : BMC Medical Research Methodology. 19, 1, 15 p., 18.

Research output: Contribution to journal › Article

122 downloads
REpeated AutoLogous Infusions of STem cells In Cirrhosis (REALISTIC): a multicentre, phase II, open-label, randomised controlled trial of repeated autologous infusions of granulocyte colony-stimulating factor (GCSF) mobilised CD133+ bone marrow stem cells in patients with cirrhosis. A study protocol for a randomised controlled trial
Andrew King, Heather Beard, Sophia Than, Chris Corbett, Daniel Hollyman, Deborah Stocken, Christina Yap, Rich Fox & Philip Newsome, 20 Mar 2015, In : BMJ open. 5, 3, e007700.

Research output: Contribution to journal › Article

122 downloads

Recent publications

A phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol
Anthony Kong, Amanda Kirkham, Jo Parish, Rachel Spruce, Gary Middleton, Christina Yap & Hisham Mehanna, 16 Mar 2020, In : BMJ open. 10, 3, e033009.

Research output: Contribution to journal › Article

A Phase II Clinical Trial with Efficacy and Toxicity Outcomes and Baseline Covariates
Kristian Brock, Cindy Billingham, Christina Yap & Gary Middleton, 27 Nov 2019, Bayesian Statistics: New Challenges and New Generations. Springer, p. 125-133 (Springer Proceedings in Mathematics & Statistics; vol. 296).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Adaptive trial designs: what is the continual reassessment method?
Gerard Millen & Christina Yap, 30 Oct 2019, In : Archives of disease in childhood. Education and practice edition. p. 1-3 3 p.

Research output: Contribution to journal › Article

View all (38)

Recent Activities

A Phase II Clinical Trial with Efficacy and Toxicity Outcomes and Baseline Covariates
Kristian Brock (Speaker), Cindy Billingham (Contributor), Gary Middleton (Contributor), Christina Yap (Contributor)
2 Jul 2018

Activity: Talk or presentation › Academic conference

Implementing more novel designs in cancer clinical trials: the Birmingham experience
Cindy Billingham (Presenter), Christina Yap (Presenter), Kristian Brock (Presenter), Daniel Slade (Presenter)
26 Mar 2018

Activity: Talk or presentation › Invited talk

Assessing the design of our trial in an ultra-rare condition by the Parmar et al framework for trials in smaller populations
Kristian Brock (Speaker), Cindy Billingham (Contributor), Christina Yap (Contributor), Timothy Barrett (Contributor)
10 Jul 2017

Activity: Talk or presentation › Academic conference

View all (4)