Christina Yap

ORCID: 0000-0002-6715-2514

Colleges, School and Institutes

Willingness to take PhD students

Yes

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Most downloaded publications

A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma
Christina Yap, Ceri Oldreive, Daniel Slade, Paul Moss & Tatjana Stankovic, Aug 2018, In : British Journal of Haematology. 182, 3, p. 429-433

Research output: Contribution to journal › Letter

139 downloads
Adaptive designs in clinical trials: why use them, and how to run and report them
Christina Yap, 28 Feb 2018, In : BMC medicine. 16, 1, 29.

Research output: Contribution to journal › Article

127 downloads
REpeated AutoLogous Infusions of STem cells In Cirrhosis (REALISTIC): a multicentre, phase II, open-label, randomised controlled trial of repeated autologous infusions of granulocyte colony-stimulating factor (GCSF) mobilised CD133+ bone marrow stem cells in patients with cirrhosis. A study protocol for a randomised controlled trial
Andrew King, Heather Beard, Sophia Than, Chris Corbett, Daniel Hollyman, Deborah Stocken, Christina Yap, Rich Fox & Philip Newsome, 20 Mar 2015, In : BMJ open. 5, 3, e007700.

Research output: Contribution to journal › Article

105 downloads
Screened selection design for randomised phase II oncology trials : an example in chronic lymphocytic leukaemia
Christina Yap & Cindy Billingham, 3 Jul 2013, In : BMC Medical Research Methodology. 13, 1, 87.

Research output: Contribution to journal › Article

99 downloads
Embracing model-based designs for dose-finding trials
Christina Yap & Charles Craddock, 25 Jul 2017, In : British Journal of Cancer. 117, 3, p. 332-339 8 p.

Research output: Contribution to journal › Article

99 downloads

Recent publications

dtpcrm: Dose Transition Pathways for Continual Reassessment Method
Christina Yap, Daniel Slade, Kristian Brock & Yi Pan, 10 Apr 2019

Research output: Non-textual form › Software

Combination Lenalidomide and Azacitidine: A Novel Salvage Therapy in Patients Who Relapse After Allogeneic Stem-Cell Transplantation for Acute Myeloid Leukemia
Charles Craddock, Daniel Slade, Carmela De Santo, Rachel Hoare, Kristian Brock, Francis Mussai & Christina Yap, 1 Mar 2019, In : Journal of Clinical Oncology . 37, 7, p. 580-588 9 p., JCO1800889.

Research output: Contribution to journal › Article

How to design a dose-finding study using the continual reassessment method
Kristian Brock, Christina Yap, 18 Jan 2019, In : BMC Medical Research Methodology. 19, 1, 15 p., 18.

Research output: Contribution to journal › Article

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Recent Activities

A Phase II Clinical Trial with Efficacy and Toxicity Outcomes and Baseline Covariates
Kristian Brock (Speaker), Cindy Billingham (Contributor), Gary Middleton (Contributor), Christina Yap (Contributor)
2 Jul 2018

Activity: Talk or presentation › Academic conference

Implementing more novel designs in cancer clinical trials: the Birmingham experience
Cindy Billingham (Presenter), Christina Yap (Presenter), Kristian Brock (Presenter), Daniel Slade (Presenter)
26 Mar 2018

Activity: Talk or presentation › Invited talk

Assessing the design of our trial in an ultra-rare condition by the Parmar et al framework for trials in smaller populations
Kristian Brock (Speaker), Cindy Billingham (Contributor), Christina Yap (Contributor), Timothy Barrett (Contributor)
10 Jul 2017

Activity: Talk or presentation › Academic conference

View all (4)