Christina Yap

ORCID: 0000-0002-6715-2514

Colleges, School and Institutes

Willingness to take PhD students

Yes

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Most downloaded publications

How to design a dose-finding study using the continual reassessment method
Kristian Brock, , , , , , , Christina Yap & , 18 Jan 2019, In: BMC Medical Research Methodology. 19, 1, 15 p., 18.

Research output: Contribution to journal › Article › peer-review

233 downloads
Adaptive designs in clinical trials: why use them, and how to run and report them
Christina Yap & , 28 Feb 2018, In: BMC medicine. 16, 1, 29.

Research output: Contribution to journal › Article › peer-review

188 downloads
A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma
Christina Yap, Ceri Oldreive, Daniel Slade, , , , , , , , , , , , , , Paul Moss & Tatjana Stankovic, Aug 2018, In: British Journal of Haematology. 182, 3, p. 429-433

Research output: Contribution to journal › Letter › peer-review

157 downloads
Embracing model-based designs for dose-finding trials
Christina Yap, , , , , , , & Charles Craddock, 25 Jul 2017, In: British Journal of Cancer. 117, 3, p. 332-339 8 p.

Research output: Contribution to journal › Article › peer-review

151 downloads
Tolerability and Clinical Activity of Post-Transplantation Azacitidine in Patients Allografted for Acute Myeloid Leukemia Treated on the RICAZA Trial
Charles Craddock, , , Christina Yap, Josephine Khan, , , Paul Ferguson, , , , Oliver Goodyear, , , , , Ram Malladi, & , 1 Feb 2016, In: Biology of Blood and Marrow Transplantation . 22, 2, p. 385–390 6 p.

Research output: Contribution to journal › Article › peer-review

137 downloads

Recent publications

Transplantation of discarded livers following viability testing with normothermic machine perfusion
Richard Laing, Amanda Kirkham, Stuart Curbishley, Desley Neil, Stefan Hubscher, Julian Bion, David Adams & 5 others, , , Christina Yap, Simon Afford & , 16 Jun 2020, In: Nature Communications. 11, 1, 2939.

Research output: Contribution to journal › Article › peer-review

Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol
Anthony Kong, , Amanda Kirkham, , , , Jo Parish, Rachel Spruce, , , , , , Gary Middleton, Christina Yap & Hisham Mehanna, 16 Mar 2020, In: BMJ open. 10, 3, e033009.

Research output: Contribution to journal › Article › peer-review

A Phase II Clinical Trial with Efficacy and Toxicity Outcomes and Baseline Covariates
Kristian Brock, Lucinda Billingham, Christina Yap & Gary Middleton, 27 Nov 2019, Bayesian Statistics: New Challenges and New Generations. Springer, p. 125-133 (Springer Proceedings in Mathematics & Statistics; vol. 296).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Recent Activities

A Phase II Clinical Trial with Efficacy and Toxicity Outcomes and Baseline Covariates

Kristian Brock (Speaker), Lucinda Billingham (Contributor), Gary Middleton (Contributor) & Christina Yap (Contributor)

2 Jul 2018

Activity: Talk or presentation › Academic conference

Implementing more novel designs in cancer clinical trials: the Birmingham experience

Lucinda Billingham (Presenter), Christina Yap (Presenter), Kristian Brock (Presenter) & Daniel Slade (Presenter)

26 Mar 2018

Activity: Talk or presentation › Invited talk

Assessing the design of our trial in an ultra-rare condition by the Parmar et al framework for trials in smaller populations

Kristian Brock (Speaker), Lucinda Billingham (Contributor), Christina Yap (Contributor) & Timothy Barrett (Contributor)

10 Jul 2017

Activity: Talk or presentation › Academic conference

View all (4)