Cedric Shackleton

(Former)

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Most downloaded publications

Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement
Angela Taylor, Petra Schneider, Jeremy Tomlinson, Donna O'Neil, Emilio Porfiri, Mark Sherlock & 5 others, Peter Nightingale, Cedric Shackleton, Paul Stewart & Wiebke Arlt, 1 Jan 2013, In : The Journal of clinical endocrinology and metabolism. 98, 1, p. 161–171

Research output: Contribution to journal › Article

500 downloads
Prenatal diagnosis of congenital adrenal hyperplasia caused by P450 oxidoreductase deficiency
Nicole Reisch, Jan Idkowiak, Vivek Dhir, Nils Krone, Cedric Shackleton & Wiebke Arlt, 1 Mar 2013, In : The Journal of clinical endocrinology and metabolism. 98, 3, p. E528-36

Research output: Contribution to journal › Article

312 downloads
Concomitant Mutations in the P450 Oxidoreductase and Androgen Receptor Genes Presenting with 46, XY Disordered Sex Development and Androgenization at Adrenarche
Jan Idkowiak, Vivek Dhir, Nicole Reisch, Donna O'Neil, Cedric Shackleton, Nils Krone & Wiebke Arlt, 1 Jul 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 7, p. 3418-3427 10 p.

Research output: Contribution to journal › Article

191 downloads
Attenuation of UVR-induced vitamin D3 synthesis in a mouse model deleted for keratinocyte lathosterol 5-desaturase
Cedric Shackleton, 19 Mar 2017, In : The Journal of Steroid Biochemistry and Molecular Biology.

Research output: Contribution to journal › Article

98 downloads
Pubertal Presentation in Seven Patients with Congenital Adrenal Hyperplasia due to P450 Oxidoreductase Deficiency.
Jan Idkowiak, Nicole Reisch, Cedric Shackleton, Nils Krone & Wiebke Arlt, 1 Mar 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 3, p. E453-62

Research output: Contribution to journal › Article

93 downloads

Recent publications

Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review
Lina Schiffer, Elizabeth Baranowski, Lorna Gilligan, Angela Taylor, Wiebke Arlt, Cedric Shackleton, 1 Nov 2019, In : The Journal of Steroid Biochemistry and Molecular Biology. 194, 25 p., 105439.

Research output: Contribution to journal › Article

Steroid metabolome analysis in disorders of adrenal steroid biosynthesis and metabolism
Lina Schiffer, Elizabeth Baranowski, Vasileios Chortis, Lorna Gilligan, Angela Taylor, Jan Idkowiak, Wiebke Arlt & Cedric Shackleton, 11 Jul 2019, In : Endocrine Reviews. 40, 6, p. 1605-1625 21 p., er.2018-00262.

Research output: Contribution to journal › Article

GC/MS has defined the normal and clinically disordered steroidome: will it be surpassed by LC/tandem MS in this role?
Cedric Shackleton, 9 Jul 2018, In : Journal of Clinical Endocrinology and Metabolism.

Research output: Contribution to journal › Article

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