Carmela De Santo

Colleges, School and Institutes

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Most downloaded publications

Combination Lenalidomide and Azacitidine: A Novel Salvage Therapy in Patients Who Relapse After Allogeneic Stem-Cell Transplantation for Acute Myeloid Leukemia
Charles Craddock, Daniel Slade, Carmela De Santo, Rachel Hoare, Kristian Brock & Christina Yap, 1 Mar 2019, In: Journal of Clinical Oncology . 37, 7, p. 580-588 9 p., JCO1800889.

Research output: Contribution to journal › Article › peer-review

178 downloads
Targeting the arginine metabolic brake enhances immunotherapy for leukaemia
Rachel Hoare, Sarah Booth, Tracey Perry, Pamela Kearns, Charles Craddock & Carmela De Santo, 28 Nov 2018, In: International Journal of Cancer.

Research output: Contribution to journal › Article › peer-review

165 downloads
Tumour-derived GM-CSF promotes granulocyte immunosuppression in mesothelioma patients
Suzanne Graef, Gary Middleton, Carmela De Santo, 30 Mar 2018, In: Clinical Cancer Research.

Research output: Contribution to journal › Article › peer-review

114 downloads
Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma
Carmela De Santo, Andrew Beggs, 18 May 2018, In: Journal of Hematology and Oncology. 11, 68.

Research output: Contribution to journal › Article › peer-review

112 downloads
The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100
Carmela De Santo, Sarah Booth, Vanessa Tubb, Tracey Perry, Boris Noyvert, Andrew Beggs, Pamela Kearns, 1 Apr 2018, In: International Journal of Cancer. 142, 7, p. 1490-1502 13 p.

Research output: Contribution to journal › Article › peer-review

92 downloads

Recent publications

Characterising EBV-associated lymphoproliferative diseases and the role of myeloid-derived suppressor cells
Paul Collins, Christopher Fox, Hayden Pearce, Gordon Ryan, Carmela De Santo, David Lewis, Heather Long & Claire Shannon-Lowe, 25 Aug 2020, In: Blood. 2020005611.

Research output: Contribution to journal › Article › peer-review

Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity
Sarah Booth, Vanessa Tubb, Andris Jankevics, Andrew Southam, Steve Lee, Warwick Dunn & Carmela De Santo, 23 Jun 2020, In: Blood.

Research output: Contribution to journal › Article › peer-review

MDSC targeting with Gemtuzumab ozogamicin restores T cell immunity and immunotherapy against cancers
Paul Collins, Suzanne Graef, Sarah Booth, Boris Noyvert, Claire Shannon-Lowe, Gary Middleton & Carmela De Santo, 1 Sep 2019, In: EBioMedicine. 47, p. 235-246 12 p.

Research output: Contribution to journal › Article › peer-review

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Recent Activities

Arginine metabolism - preclinical findings and therapeutic opportunities

(Chair) & Carmela De Santo (Chair)

7 Mar 2017

Activity: Talk or presentation › Invited talk

View all (1)