Willingness to take PhD students
Andrew Hislop is a viral immunologist with an interest in how T lymphocytes control oncogenic human viruses and how these viruses evade recognition and clearance by such immune effectors. His studies focus on Kaposi sarcoma-associated herpesvirus, Epstein-Barr virus and Merkel cell virus.
As part of their biology of infection, some viruses can induce entry of the cell into cycle. If the viral genome is maintained in the cell episomally or through integration into the host genome, this can lead to the proliferation of these infected cells and ultimately to the development of cancer.
A vital control mechanism in this process is the immune response, particularly the T lymphocyte component of the antiviral response. Andrew's group studies which viral antigens T lymphocytes respond to, how these T cells recognise virally infected cells and how the viruses evade T cell recognition and clearance. The viruses that the group studies are Epstein-Barr virus, Kaposi sarcoma-associated herpesvirus, and Merkel cell polyomavirus.
Dr Hislop supervises doctoral research in the field of immunity to oncogenic virus infections.