Willingness to take PhD students
Ana Maria Gonzalez’s research and doctoral supervision focuses on the evaluation of strategies to deliver gene biotherapeutics into the CNS. While the genes that can alter the natural course of neuronal injury response are known, their therapeutic potential has not been realised due to ineffective delivery to neurons. Accordingly there is a need for novel approaches to increase the efficiency and specificity of biotherapeutic delivery. Research is currently ongoing in developing gene-activated matrices (GAM) that can selectively deliver genes to specific populations of neurons and glia in the CNS. Two areas of particular interest are: Cerebrospinal fluid homeostasis, neurohormone homeostasis and neuroprogenitor fate and function in neurodegeneration and after traumatic brain injury Drug and biotherapeutic delivery to the CNS after injury.