Alice Pollitt

(Former)

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Most downloaded publications

Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling
Leyre Navarro-Nunez, Alice Pollitt, Kate Lowe, Gerard Nash & Steve Watson, May 2015, In : Thrombosis and Haemostasis. 113, 5, p. 1109-1120

Research output: Contribution to journal › Article

253 downloads
Platelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich Syndrome protein and ARP2/3 complex
Natalie Poulter, Alice Pollitt, Joshua Rappoport, Gerard Nash, Mike Hannon, Zoe Pikramenou, Steve Watson, Steven Thomas & Dylan Owen, 1 Jun 2015, In : Nature Communications. 6, 7254.

Research output: Contribution to journal › Article

181 downloads
Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization, secondary mediators, and Rac
Alice Pollitt & Steve Watson, 1 Apr 2010, In : Blood. 115, 14, p. 2938-2946 9 p.

Research output: Contribution to journal › Article

153 downloads
CLEC-2 activates Syk through dimerization
Craig Hughes, Alice Pollitt, Jun Mori, Michael Tomlinson, Klaus Futterer & Steve Watson, 12 Feb 2010, In : Blood. 115, 14, p. 2947-2955

Research output: Contribution to journal › Article

142 downloads
The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC-2 signalling in platelets.
Jennifer Spalton, Alice Pollitt, Craig Hughes & Steve Watson, 24 Apr 2009, In : Journal of Thrombosis and Haemostasis.

Research output: Contribution to journal › Article

137 downloads

Recent publications

Low dose Btk inhibitors selectively block platelet activation by CLEC-2
Christopher Smith, Joana Campos, Alexander Brill, Jeremy Pike, Abdullah Khan, Natalie Poulter, Deirdre Kavanagh, Aarnoud Huissoon, Alice Pollitt, Dickens Pratt, Steve Watson & Craig Hughes, 15 Jan 2020, (Accepted/In press) In : Haematologica.

Research output: Contribution to journal › Article

Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets
Natalie Poulter, Alice Pollitt, Dylan Owen, Steve Watson, 6 Jan 2017, In : Journal of thrombosis and haemostasis : JTH. 15, 3, p. 549-564

Research output: Contribution to journal › Article

Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands
Alice Pollitt, Craig Hughes & Steve Watson, 15 Jun 2015, In : Biochem J. 468, 3, p. 459-73 15 p.

Research output: Contribution to journal › Article

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