Alexander Brill

Colleges, School and Institutes

Willingness to take PhD students

Yes

PhD projects

Alex Brill researches different models of thrombosis, inflammation and microscopy. His main research interests are mechanisms of cardiovascular diseases, such as deep vein thrombosis and stroke, and identifying new targets to prevent and treat these disorders.

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Most downloaded publications

Large scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming
Moreau, T., Evans, A., Vasquez, L., Tijssen, M., Yan, Y., Alexander Brill & Ghevaert, C., 7 Apr 2016, In : Nature Communications. 7, p. 1-15 11208.

Research output: Contribution to journal › Article

200 downloads
Modelling and simulation of flow and agglomeration in deep veins valves using discrete multi physics
Ariane, M., Wen, W., Daniele Vigolo, Alexander Brill, Nash, F. G. B., Mostafa Barigou & Alessio Alexiadis, 1 Oct 2017, In : Computers in Biology and Medicine. 89, p. 96-103 8 p.

Research output: Contribution to journal › Article

85 downloads
Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice
Shaw, M., Kombrinck, K., McElhinney, K., Sweet, D., Flick, M., Palumbo, J., Cheng, M., Esmon, N., Esmon, C., Alexander Brill, Wagner, D., Degen, J. & Mullins, E., 4 Aug 2016, In : Blood. 128, 5, p. 721-731

Research output: Contribution to journal › Article

82 downloads
Mice with a deficiency in CLEC-2 are protected against deep vein thrombosis
Payne, H., Tatyana Ponomaryov, Steve Watson & Alexander Brill, 2017, In : Blood. 129, 14, p. 2013-2020

Research output: Contribution to journal › Article

60 downloads
Using Discrete Multi-Physics for studying the dynamics of emboli in flexible venous valves
Ariane, M., Daniele Vigolo, Alexander Brill, Gerard Nash, Mostafa Barigou & Alessio Alexiadis, 30 Apr 2018, In : Computers and Fluids. 166, p. 57-63 7 p.

Research output: Contribution to journal › Article

60 downloads

Recent publications

Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells
Noy, P. J., Gavin, R. L., Colombo, D., Haining, E. J., Reyat, J. S., Payne, H., Thielmann, I., Lokman, A. B., Neag, G., Yang, J., Lloyd, T., Harrison, N., Heath, V. L., Gardiner, C., Whitworth, K. M., Robinson, J., Koo, C. Z., Di Maio, A., Harrison, P., Lee, S. P. & 7 others, Michelangeli, F., Neena Kalia, Ed Rainger, Nieswandt, B., Alexander Brill, Steve Watson & Michael Tomlinson, Sep 2019, In : Haematologica. 104, 9, p. 1892-1905 34 p.

Research output: Contribution to journal › Article

Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation
Chimen, M., Evryviadou, A., Box, C. L., Harrison, M. J., Hazeldine, J., Dib, L. H., Kuravi, S. J., Payne, H., Price, J. M. J., Kavanagh, D., Iqbal, A. J., Lax, S., Kalia, N., Brill, A., Thomas, S. G., Belli, A., Crombie, N., Adams, R. A., Evans, S-A., Deckmyn, H. & 5 others, Janet Lord, Paul Harrison, Steve Watson, Gerard Nash & Ed Rainger, 23 Aug 2019, (Accepted/In press) In : Haematologica.

Research output: Contribution to journal › Article

Podoplanin regulates the migration of mesenchymal stromal cells and their interaction with platelets.
Ward, L. S. C., Lozan Sheriff, Jennifer Marshall, Manning, J. E., Alexander Brill, Gerard Nash & Helen McGettrick, 25 Feb 2019, In : Journal of Cell Science. 132, 5, 12 p., jcs222067.

Research output: Contribution to journal › Article

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