Microbiology and Infection

Organisational unit: School

Publications

  1. 2021
  2. Published
  3. Published

    Airway microbial communities, smoking and asthma in a general population sample

    Michael Cox, , , , , , , , & , Sep 2021, In: EBioMedicine. 71, 9 p., 103538.

    Research output: Contribution to journalArticlepeer-review

  4. Published
  5. Published
  6. E-pub ahead of print
  7. E-pub ahead of print
  8. Published

    The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN

    Peter Searle, Eva Hyde & Scott White, 16 Jul 2021, In: The Biochemical journal. 478, 13, p. 2601-2617 17 p.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    CD1a selectively captures endogenous cellular lipids that broadly block T cell response

    Natacha Veerapen, , , , , , , , , , Del Besra, , & , 5 Jul 2021, In: The Journal of Experimental Medicine. 218, 7, 20 p., e20202699.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    A multi-targeting pre-clinical candidate against drug-resistant tuberculosis

    Sarah Batt, Emily Richardson, , Del Besra, & , Jul 2021, In: Tuberculosis. 129, 11 p., 102104.

    Research output: Contribution to journalArticlepeer-review

  11. Published
  12. Published

    HRMAn 2.0: Next-generation artificial intelligence-driven analysis for broad host-pathogen interactions

    Barbara Clough, , , & Eva Frickel, Jul 2021, In: Cellular Microbiology. 23, 7, p. e13349

    Research output: Contribution to journalArticlepeer-review

  13. Published

    Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

    & 9 others, , , , , , , , & , 29 Jun 2021, In: Cell Reports. 35, 13, 24 p., 109292.

    Research output: Contribution to journalArticlepeer-review

  14. Published

    Carbapenem and colistin resistance in Enterobacter: determinants and clones

    Alan McNally, Jun 2021, In: Trends in Microbiology. 29, 6, p. 473-476 4 p.

    Research output: Contribution to journalArticlepeer-review

  15. Published

    Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

    Alan McNally, 13 May 2021, In: Nature. 593, 7858, p. 266–269 4 p.

    Research output: Contribution to journalArticlepeer-review

  16. Published

    Discovery of novel thiophene-arylamide derivatives as DprE1 inhibitors with potent antimycobacterial activities

    Sarah Batt, , , , , , Del Besra & , 13 May 2021, In: Journal of Medicinal Chemistry. 64, 9, p. 6241-6261 21 p.

    Research output: Contribution to journalArticlepeer-review

  17. Published

    Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria

    Jessica Blair & , 12 May 2021, In: Chemical Reviews. 121, 9, p. 5479-5596 118 p.

    Research output: Contribution to journalArticlepeer-review

  18. Published

    The effect of intramuscular injection technique on injection associated pain; a systematic review and meta-analysis

    3 May 2021, In: PLoS ONE. 16, 5, e0250883.

    Research output: Contribution to journalArticlepeer-review

  19. E-pub ahead of print
  20. Published

    Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study

    May 2021, In: The Lancet. Public health. 6, 5, p. e335-e345 11 p.

    Research output: Contribution to journalArticlepeer-review

  21. Published
  22. Published
  23. Published
  24. Published
  25. Published
  26. Published
  27. Published
  28. E-pub ahead of print

    Biochemical and phenotypic characterisation of the Mycobacterium smegmatis transporter UspABC

    Apoorva Bhatt, , , Del Besra & , Dec 2021, In: The Cell Surface. 7, 12 p., 100052.

    Research output: Contribution to journalArticlepeer-review

  29. E-pub ahead of print
  30. Published
  31. Published

    Backbone assignment of E. coli NfsB and the effects of addition of the cofactor analogue nicotinic acid

    Eva Hyde, & , 1 Apr 2021, In: Biomolecular NMR assignments. 15, 1, p. 143-151 9 p.

    Research output: Contribution to journalArticlepeer-review

  32. Published
  33. Published

    Pellicle formation by Escherichia coli K-12: role of adhesins and motility

    Tim Overton, Apr 2021, In: Journal of Bioscience and Bioengineering. 131, 4, p. 381-389 9 p.

    Research output: Contribution to journalArticlepeer-review

  34. Published

    Synthesis and recycling of the mycobacterial cell envelope

    Katherine Abrahams & Del Besra, Apr 2021, In: Current Opinion in Microbiology. 60, p. 58-65 8 p.

    Research output: Contribution to journalReview articlepeer-review

  35. Published
  36. Published
  37. Published
  38. Published
  39. Published

    Neurodegenerative disease and the NLRP3 inflammasome

    Samuel Lara Reyna, , , & , 10 Mar 2021, In: Frontiers in Pharmacology. 12, 15 p., 643254.

    Research output: Contribution to journalReview articlepeer-review

  40. Published
  41. Published

    Acetylcholine production by group 2 innate lymphoid cells promotes mucosal immunity to helminths

    David Withers, Bill Horsnell & , 5 Mar 2021, In: Science Immunology. 6, 57, eabd0359.

    Research output: Contribution to journalArticlepeer-review

  42. Published
  43. Published

    What makes new variants of SARS-CoV-2 concerning is not where they come from, but the mutations they contain

    Alan McNally, 22 Feb 2021, In: BMJ. 372, n504.

    Research output: Contribution to journalComment/debate

  44. Published

    Evaluation of full-length nanopore 16S sequencing for detection of pathogens in microbial keratitis

    Saaeha Rauz, 15 Feb 2021, In: PeerJ. 9, 24 p., e10778.

    Research output: Contribution to journalArticlepeer-review

  45. E-pub ahead of print
  46. Published

    Immune Sensing of Candida albicans

    Ebrima Bojang, , & , 6 Feb 2021, In: Journal of Fungi. 7, 2, 119.

    Research output: Contribution to journalReview articlepeer-review

  47. Published
  48. Published

    Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2

    Eleyna Martin, Alexandre Slater, , , Steve Watson & Julie Rayes, Feb 2021, In: Haematologica. 106, 2, p. 626-629 4 p.

    Research output: Contribution to journalReview articlepeer-review

  49. Published
  50. E-pub ahead of print
  51. Published

    Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity

    Samuel Nicholls & 12 others, , , , , , , Nicholas Loman, , , , & , 7 Jan 2021, In: Cell. 184, 1, p. 64-75.e11 24 p.

    Research output: Contribution to journalArticlepeer-review

  52. Published

    Harder, better, faster, stronger: colistin resistance mechanisms in Escherichia coli

    Willem van Schaik, 7 Jan 2021, In: PLoS Genetics. 17, 1, e1009262.

    Research output: Contribution to journalArticlepeer-review

  53. Published
  54. Published

    Chemical insights into the search for MAIT cells activators

    Natacha Veerapen, , & Del Besra, Jan 2021, In: Molecular immunology. 129, p. 114-120 7 p.

    Research output: Contribution to journalArticlepeer-review

  55. Published
  56. 2020
  57. E-pub ahead of print

    Antimicrobial resistance and gene regulation in Enteroaggregative Escherichia coli from Egyptian children with diarrhoea: similarities and differences

    Steve Busby & Doug Browning, 29 Dec 2020, (E-pub ahead of print) In: Virulence. 12, 1, p. 57-74 18 p.

    Research output: Contribution to journalArticlepeer-review

  58. E-pub ahead of print

    ILC3-derived acetylcholine promotes protease-driven allergic lung pathology

    Bill Horsnell, 19 Dec 2020, (E-pub ahead of print) In: Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticlepeer-review

  59. Published
  60. E-pub ahead of print

    Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in Mycobacterium tuberculosis

    Katherine Abrahams, , , , , Del Besra, & , 15 Dec 2020, (E-pub ahead of print) In: ACS Infectious Diseases.

    Research output: Contribution to journalArticlepeer-review

  61. E-pub ahead of print
  62. E-pub ahead of print

    Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

    8 Dec 2020, (E-pub ahead of print) In: The Lancet. 397, 10269, p. 99-111 13 p.

    Research output: Contribution to journalArticlepeer-review

  63. Published

    Mycobacterial drug discovery

    Katherine Abrahams & Del Besra, 1 Dec 2020, In: RSC Medicinal Chemistry. 11, 12, p. 1354-1365

    Research output: Contribution to journalArticlepeer-review

  64. Published

    Tuberculosis diagnostics: overcoming ancient challenges with modern solutions

    Sam Wilkinson, Del Besra & Pola Goldberg Oppenheimer, 1 Dec 2020, In: Emerging topics in life sciences. 4, 4, p. 423-436 14 p.

    Research output: Contribution to journalArticlepeer-review

  65. Published
  66. Published

    Anti-tubercular derivatives of rhein require activation by the monoglyceride lipase Rv0183

    Katherine Abrahams, , , , Emily Richardson, , & Del Besra, Dec 2020, In: The Cell Surface. 6, 9 p., 100040.

    Research output: Contribution to journalArticlepeer-review

  67. Published

    Antibiotics and resistance: the two-sided coin of the mycobacterial cell wall

    Sarah Batt, , & Del Besra, Dec 2020, In: The Cell Surface. 6, 100044.

    Research output: Contribution to journalReview articlepeer-review

  68. Published

    Cointegration as a mechanism for the evolution of a KPC-producing multidrug resistance plasmid in Proteus mirabilis

    Robert Moran, , , Willem van Schaik & , Dec 2020, In: Emerging Microbes and Infections. 9, 1, p. 1206-1218 13 p.

    Research output: Contribution to journalArticlepeer-review

  69. Published

    Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells

    Beth Lucas, , Emilie Cosway, , , Nick Jones, , , & Graham Anderson, Dec 2020, In: Nature Communications. 11, 1, 14 p., 2198.

    Research output: Contribution to journalArticlepeer-review

  70. Published

    Identification and validation of the mode of action of the chalcone anti-mycobacterial compounds

    Del Besra, , , & , Dec 2020, In: The Cell Surface. 6, p. 100041 100041.

    Research output: Contribution to journalArticlepeer-review

  71. Published
  72. Published

    Post-acute COVID-19 associated with evidence of bystander t-cell activation and a recurring antibiotic-resistant bacterial pneumonia

    & 10 others, , , , , Samuel Nicholls, , Nicholas Loman, Michael Cox, & , Dec 2020, In: eLife. 9, p. 1-13 13 p., e63430.

    Research output: Contribution to journalArticlepeer-review

  73. Published
  74. Published
  75. Published
  76. Published

    Pooled testing for SARS-CoV-2 could provide the solution to UK's testing strategy

    Alan McNally, 9 Nov 2020, In: BMJ. 371, p. m4312

    Research output: Contribution to journalArticle

  77. Published

    Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB

    Vito Ricci, , , , , , , , , , , & , 4 Nov 2020, In: Nature Communications. 11, 1, p. 5565

    Research output: Contribution to journalArticlepeer-review

  78. Published
  79. E-pub ahead of print

    How to establish an academic SARS-CoV-2 testing laboratory

    Alex Richter, , , , , , , , Thomas White, , Jeremy Mirza, & Alan McNally, 2 Nov 2020, (E-pub ahead of print) In: Nature Microbiology.

    Research output: Contribution to journalArticle

  80. Published

    Do phenothiazines possess antimicrobial and efflux inhibitory properties?

    Laura Piddock, Nov 2020, In: FEMS Microbiology Reviews. 43, 6, p. 577-590 14 p.

    Research output: Contribution to journalReview articlepeer-review

  81. Published

    A Bayesian non-parametric mixed-effects model of microbial growth curves

    Peter Lund, & , 26 Oct 2020, In: PLoS Computational Biology. 16, 10, p. e1008366 e1008366.

    Research output: Contribution to journalArticlepeer-review

  82. Published

    Lopinavir–ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

    24 Oct 2020, In: The Lancet. 396, 10259, p. 1345-1352 8 p.

    Research output: Contribution to journalArticlepeer-review

  83. Published
  84. E-pub ahead of print

    Scientific consensus on the COVID-19 pandemic: we need to act now

    Alan McNally & 11 others, , , , , , , , , , & , 15 Oct 2020, (E-pub ahead of print) In: The Lancet.

    Research output: Contribution to journalArticle

  85. Published

    Serogroups of Dichelobacter nodosus, the cause of footrot in sheep, are randomly distributed across England

    Laura Green & , 8 Oct 2020, In: Scientific Reports. 10, 1, 16823.

    Research output: Contribution to journalArticlepeer-review

  86. Published

    Overlapping activities of ELAV/Hu family RNA binding proteins specify the extended neuronal 3' UTR landscape in Drosophila

    Matthias Soller & , 1 Oct 2020, In: Molecular Cell. 80, 1, p. 140-155.e6 23 p.

    Research output: Contribution to journalArticlepeer-review

  87. Published

    Understanding How Microorganisms Respond to Acid pH Is Central to Their Control and Successful Exploitation

    Peter Lund, , , , , , , , , & , 24 Sep 2020, In: Frontiers in Microbiology. 11, p. 556140 556140.

    Research output: Contribution to journalArticlepeer-review

  88. E-pub ahead of print

    Oldest evidence of tuberculosis in Argentina: A multidisciplinary investigation in an adult male skeleton from Saujil, Tinogasta, Catamarca (905-1030 CE)

    Oona Lee, , Del Besra, David Minnikin, , & , 22 Sep 2020, (E-pub ahead of print) In: Tuberculosis. 125, p. 101995 101995.

    Research output: Contribution to journalArticlepeer-review

  89. Published
  90. Published

    A call for action to the biomaterial community to tackle antimicrobial resistance

    Thomas Hall, Victor M. Villapun, Owen Addison, Mark Webber, Morgan Lowther, , , & Sophie Cox, 21 Sep 2020, In: Biomaterials Science. 8, 18, p. 4951-4974

    Research output: Contribution to journalArticlepeer-review

  91. Published
  92. Published
  93. E-pub ahead of print

    COVID-19: medical students in clinical research

    Christopher Green, 27 Aug 2020, (E-pub ahead of print) In: The Clinical Teacher.

    Research output: Contribution to journalArticlepeer-review

  94. Published

    Conditionally essential genes for survival during starvation in Enterococcus faecium E745

    Willem van Schaik, 18 Aug 2020, In: BMC Genomics. 21, 1, p. 568

    Research output: Contribution to journalArticlepeer-review

  95. Published
  96. E-pub ahead of print
  97. Published

    Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown

    Lucy Crouch & 1 others, , 11 Aug 2020, In: Nature Communications. 11, 1, 4017.

    Research output: Contribution to journalArticlepeer-review

  98. Published
  99. Published
  100. Published

    Letter: faecal microbiota transplantation for IBS

    Mohammed Nabil Quraishi & Tariq Iqbal, Aug 2020, In: Alimentary Pharmacology & Therapeutics. 52, 3, p. 556-557 2 p.

    Research output: Contribution to journalArticlepeer-review

  101. E-pub ahead of print
  102. Published
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