Metabolism and Systems Research
Organisational unit: School
Research Projects
Research Training Support (RTS) Award
WEST MIDLANDS STRATEGIC HEALTH AUTHORITY
1/10/09 → 31/10/11
Project: Research
Synergistic Effects of Physical and Psychological Stress Upon Immunesenescence
Janet Lord, Anna Whittaker, Wiebke Arlt, Doug Carroll, Glyn Humphreys, Jan Oyebode & Cath Sackley
ECONOMIC & SOCIAL RESEARCH COUNCIL
1/10/09 → 31/12/12
Project: Research Councils
The effect of the GLP-1 agonist liraglutide on non-alcoholic steatohepatitis in patients with and without type 2 diabetes mellitus
Philip Newsome & Jeremy Tomlinson
THE WELLCOME TRUST, NOVO NORDISK PHARMACEUTICALS LTD
1/10/09 → 31/12/16
Project: Research
Thyroid Hormone Action in the Decidua During Human Pregnancy
Shiaoyng Chan, Jayne Franklyn, Mark Kilby & Laurence Loubiere
WELLBEING OF WOMEN
1/10/09 → 28/02/13
Project: Research
The Role of PTTG and PBF in Genomic Stability and DNA Repair in Thyroid Cancer
THE WELLCOME TRUST
28/09/09 → 27/09/11
Project: Research
A multicentre, prospective, long-term registry of paediatric patients with Crohn's disease
BIRMINGHAM CHILDRENS HOSPITAL
1/09/09 → 31/03/19
Project: Research
Investigating Hexose-6-Phosphate Dehydrogenase in the Control of Skeletal Muscle Function and Carbohydrate Metabolism
BIOTECHNOLOGY & BIOLOGICAL SCIENCES
1/09/09 → 31/08/14
Project: Research Councils
Novel Binding Partners of PBF in Thyroid Tumours
ROYAL COLLEGE OF SURGEONS
1/09/09 → 31/08/10
Project: Research
Prenatal Detection of Chromosomal Anomalies Using Microarrays in Prenatally Diagnosed Congenital Cardiac Disease and Associated Anomalies
SPORT AIDING MEDICAL RESEARCH FOR KIDS
1/09/09 → 14/03/13
Project: Research
Differential Roles of PAPSS1 and PAPSS2 in the Control of Androgen Synthesis
SOCIETY FOR ENDOCRINOLOGY
22/06/09 → 21/08/09
Project: Research
Screening Six Novel Candidate Gene Regions For Association with Graves' Disease
SOCIETY FOR ENDOCRINOLOGY
22/06/09 → 21/08/09
Project: Research
Can Enhanced Glycaemic Control in Type II Diabetics Improtve Myocardial Protection
, Michael Frenneaux, Martin Stevens & Jon Townend
BRITISH HEART FOUNDATION
4/05/09 → 31/08/12
Project: Research
Wellcome Trust VIP Award - Dr Simmonds Training Visit
THE WELLCOME TRUST
1/05/09 → 30/09/09
Project: Research
Type 2 Diabetes in Childhood: Building a Platform to Support Novel Intervention Strategies (Jump Study)
Timothy Barrett & Tony Barnett
MEDICAL RESEARCH COUNCIL
27/04/09 → 26/04/14
Project: Research Councils
Steroid Profiling as a Biomarker Tool in the Diagnosis and Monitoring of Adrenal Tumours
MEDICAL RESEARCH COUNCIL
2/03/09 → 29/02/12
Project: Research Councils
Investigations on The Putative Role of IGHMBP2 in The Regulation of Androgen Synthesis
EUROPEAN SOCIETY FOR PAEDIATRIC ENDOCRINOLOGY
1/01/09 → 30/04/11
Project: EU
The role of 5-alpha reductase in the modulation of non-alcoholic steatohepatitis
Philip Newsome & Jeremy Tomlinson
THE WELLCOME TRUST
1/12/08 → 30/11/11
Project: Research
Type 2 Diabetes Mellitus and its Microvascular Complications in South Asians in the UK
NIHR TRAINEES COORDINATING CENTRE
3/11/08 → 2/11/11
Project: Research
Monocarboxylate Transporter 10 (MCT10) in Human Placental Development and in the Pathophysiology of Intrauterine Growth-Restriction (IUGR)
Mark Kilby, Shiaoyng Chan, Jayne Franklyn & Laurence Loubiere
ACTION MEDICAL RESEARCH
1/11/08 → 31/10/10
Project: Research
CLAHRC Theme 8 - Flexibiltiy and Sustainability Funding
NIHR
1/10/08 → 31/03/14
Project: Other Government Departments
Defining the Interaction between P53, PBF and PTR in Thyroid Cancer
UHB CHARITABLE FUNDS
1/10/08 → 31/01/10
Project: Research
Theme 8 - Implementation of Effective Community Care for Diabetes
Shahrad Taheri, Richard Lilford, Parth Narendran &
NIHR, LILLY RESEARCH CENTRE LIMITED, LILLY HUNGARIA KFT, BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST, LILLY REGIONAL OPERATIONS GMBH, ELI LILLY SLOVAKIA S.R.O.
1/10/08 → 31/12/13
Project: Research
The PLUTO Trial: Percutaneous Shunting in Lower Urinary Tract Obstruction
Mark Kilby, R. Katie Morris, Jane Daniels, Khalid Khan, Lee Middleton, Stirling Bryan, Tracy Roberts, Celia Taylor, Richard Gray, Richard Lilford &
THE NHS HEALTH TECHNOLOGY ASSESMENT PROGRAMME (HTA)
1/09/08 → 30/06/12
Project: Research
Clinical Morphological and Biomarker Investigation of Endometrial Hyperplasia before and following Treatment with Levonorgestrel-releasing Intrauterine System (LNG-IUS)
WELLBEING OF WOMEN
31/08/08 → 30/09/11
Project: Research
Clinical research infrastructure and trials platforms (Science City : Translational Medicine) - Bid 1
Lucinda Billingham, Helen Cooper, Klaus Futterer, Glyn Humphreys, John Jefferys, Philip Johnson, Jackson Kirkman-Brown, Gregory Lip, Ashley Martin, Michael Overduin, Charles Penn, Joshua Rappoport, Jane Steele, Jeremy Tomlinson, Mark Viant, Mark Wheatley & Paul Stewart
Advantage West Midlands
14/08/08 → 31/03/12
Project: Other Government Departments
TM2 : EXPERIMENTAL MEDICINE NETWORK OF EXCELLENCE (Science City : Translational Medicine) - Bid 2
Lucinda Billingham, Helen Cooper, Klaus Futterer, Glyn Humphreys, John Jefferys, Philip Johnson, Jackson Kirkman-Brown, Gregory Lip, Ashley Martin, Michael Overduin, Charles Penn, Joshua Rappoport, Jane Steele, Jeremy Tomlinson, Mark Viant, Mark Wheatley & Paul Stewart
Advantage West Midlands
14/08/08 → 31/03/19
Project: Other Government Departments
Study of the Biological and Clinical Significance of Maternal Cellular Immunity to Fetal Antigens
WELLBEING OF WOMEN, BRITISH MATERNAL AND FETAL MEDICINE SOCIETY
4/08/08 → 30/11/15
Project: Research
Establishing a DNA Resource to Study Genetic Susceptibility to Type 2 Diabetes and its Complications in a Population of Mirpuri Origin from Pakistan
Ann (Wilson) Kelly & Tony Barnett
DIABETES UK
1/07/08 → 30/06/09
Project: Research
Screening the NDLBP Region for Association with Greaves Disease
SOCIETY FOR ENDOCRINOLOGY
1/07/08 → 31/08/08
Project: Research
Characterisation and Function of Ectopic Proinsulin Expression
Parth Narendran, Stephen Gough & David Sansom
DIABETES UK, UNIVERSITY HOSPITAL BIRMINGHAM NHS FOUNDATION TRUST
1/06/08 → 31/05/11
Project: Research
FP7_Collab - EURODSD : Investigation of the Molecular Pathogenesis & Pathophysiology of Disorder of Sex Development (DSD).
EUROPEAN COMMISSION, European Commission - Management Costs
1/05/08 → 31/10/11
Project: Research
The Diagnostic/Prognostic Value of Neonatal Findings for Predicting Childhood and Adult Morbidity: Systematic Reviews, Meta-Analysis and Decision Analytic Modelling
BIRMINGHAM WOMEN'S CHARITABLE FUNDS
1/05/08 → 31/12/13
Project: Research
Glucocorticoid Metabolism in Osteosarcoma: Role in Pathogenesis and Potential for Targeted Treatment
UHB CHARITABLE FUNDS
1/04/08 → 31/05/10
Project: Research
FP7 MC - AA: Adrenal Andogens.
European Commission - Management Costs, EUROPEAN COMMISSION
18/02/08 → 17/02/10
Project: Research
Clinical Thyroid Databases - Long Term Morbidity and Mortality studies in Patients with Treated Thyroid Disease.
UHB CHARITABLE FUNDS
10/01/08 → 9/01/10
Project: Research
Life Course Pathways to Ageing: MRC National Survey of Health & Develop
MEDICAL RESEARCH COUNCIL
1/01/08 → 30/04/11
Project: Research Councils
Prediction and Prevention of Fetal Growth Restriction and Compromise of Fetal Wellbeing. Systematic Reviews and Meta-Analyses with Model-Based Economic Evaluation
MEDICAL RESEARCH COUNCIL
1/01/08 → 30/06/10
Project: Research Councils
New Mechanisms of Sodium Iodide Symporter Repression
Christopher McCabe, Kristien Boelaert & Jayne Franklyn
MEDICAL RESEARCH COUNCIL
1/12/07 → 28/02/11
Project: Research Councils
The Effects of Tri-Iodothyronine and Methylprednisolone on the Suitability of Donor Hearts for Transplantation?
, Christopher McCabe, Jayne Franklyn &
BRITISH HEART FOUNDATION
1/11/07 → 28/02/09
Project: Research
Modelling Nuclear Receptor and NCoR1 Interactions
BREAST CANCER CAMPAIGN
4/10/07 → 30/04/10
Project: Research
Investigation of the molecular mechanism responsible for the sexual dimorphism in cortisol metabolism & 111B-hydroxysteriod dehydrogenase type 1 activity
UNILEVER RESEARCH
1/10/07 → 30/09/11
Project: Industry
Local Glucocorticoid Metabolism in Inflammatory Arthritis
Mark Cooper, Karim Raza, Christopher Buckley, Elizabeth Rabbitt & Paul Stewart
ARTHRITIS RESEARCH CAMPAIGN
1/10/07 → 31/05/11
Project: Research
Complex Modulation of Human Sperm Behaviour by Olfactory Receptors
BRITISH COUNCIL
1/08/07 → 31/03/09
Project: Other Government Departments
Corticosteroids, Intercranial Pressure and the Pathogenesis of Idiopathic Intercranial Hypertension
Saaeha Rauz, Elizabeth Walker, Alex Sinclair & Paul Stewart
MIDLAND NEUROSCIENCE TEACHING & RESEARCH FUND
1/07/07 → 30/06/12
Project: Research
Corticosteroids, Intracranial Pressure and the Pathogenesis of Idiopathic Intracranial Hypertension
Saaeha Rauz, Elizabeth Walker, Alex Sinclair & Paul Stewart
MEDICAL RESEARCH COUNCIL
1/07/07 → 30/06/10
Project: Research Councils
Endocrine Function in Steroid Sulphatase Deficiency (The STS Study)
Wiebke Arlt, &
BIRMINGHAM CHILDRENS HOSPITAL RESEARCH FOUNDATION
1/07/07 → 31/12/08
Project: Research
Novel Pathways Promoting Thyroid Tumourigenesis and Growth
Kristien Boelaert, Jayne Franklyn, Lawrence Young & Christopher McCabe
MEDICAL RESEARCH COUNCIL
1/07/07 → 30/11/11
Project: Research Councils
Pulse Oximetry as a Screening Test for Congenital Heart Disease in Newborn Babies
Andrew Ewer, Jane Daniels, Tracy Roberts, Khalid Khan, Jon Deeks & Shakila Thangaratinam
THE NHS HEALTH TECHNOLOGY ASSESMENT PROGRAMME (HTA)
1/07/07 → 30/09/10
Project: Research
Can hysterectemies be avoided in women with non-atypical endometrial hyperplasia by evaluating immumhistochemical features that may be predictive of persistence or progression of enometrial hyperplasia
BIRMINGHAM WOMENS NHS TRUST
1/05/07 → 31/03/14
Project: Research
VIP - JC Kirkman Brown - To learn molecular , culture and chemical techniques for the expression and characterisation of functional Olfactory GProtein coupled receptors in vitro
THE WELLCOME TRUST
1/05/07 → 30/09/07
Project: Research
The Role of Local Glucocorticoid Metabolism in Idiopathic, Age-Related and Glucocorticoid-Induced Bone Disease
Mark Cooper, Elizabeth Rabbitt & Paul Stewart
ARTHRITIS RESEARCH CAMPAIGN
1/04/07 → 30/09/10
Project: Research
Does Adiponectin influence the loss of T-Cell tolerance and the development of Type 1 diabetes?
UHB NHS TRUST, DIABETES RESEARCH WELLNESS FOUNDATION
26/03/07 → 25/12/09
Project: Research
Abnormal sulphur metabolism in the pathogenesis of gastrointestinal disease
Jeff Cole, David Ramsden & Rosemary Waring
THE WELLCOME TRUST
1/03/07 → 31/07/10
Project: Research
Topical Retinoids and Diabetic Neuropathic Ulceration
DIABETES UK, BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/03/07 → 31/10/10
Project: Research
Adverse Effects of Glucocorticoid Therapy on Bone in Childhood Crohn's Disease
Stephen Murphy, Mark Cooper, & Carole Cummins
BIRMINGHAM CHILDRENS HOSPITAL RESEARCH FOUNDATION
19/02/07 → 31/07/08
Project: Research
SCOOP : A Pragmatic Randomised Controlled Trial of the Effectiveness and Cost Effectiveness of Screening for Osteoporosis in Older Women for the Prevention of Fractures
MEDICAL RESEARCH COUNCIL
1/02/07 → 31/12/15
Project: Research Councils
The Role of Monocarboxylate Transporter 8 During Human Placental Development in Normal and IUGR Pregnancies
Shiaoyng Chan, Jayne Franklyn, Mark Kilby & Christopher McCabe
MEDICAL RESEARCH COUNCIL
3/01/07 → 2/01/09
Project: Research Councils
The Role Of PTTG and PBF In Thyroid and Other Cancers
UHB CHARITABLE FUNDS, GET A HEAD CHARITABLE TRUST
1/01/07 → 1/08/11
Project: Research
Amniotic Fluid Cytokine Response and Maternal Placental Angiogenic Growth Factor Concentrations in Twin-to-Twin Transfusion Syndrome: The Response to Fetal Therapy
WELLBEING OF WOMEN
1/12/06 → 31/12/12
Project: Research
The Role of Redox Potential Regulation in the Molecular Pathogenesis of Congenital Adrenal Hyperplasia
THE WELLCOME TRUST
1/12/06 → 30/11/11
Project: Research
Monocarboxylate Transporter 8 in Human Central Nervous System Development and the Effects of Intrauterine Growth Restriction
Jayne Franklyn, Shiaoyng Chan, Mark Kilby, Ann Logan & Christopher McCabe
ACTION MEDICAL RESEARCH
27/11/06 → 26/05/08
Project: Research
A near-patient Test for Male Fertility
Christopher Barratt & Jackson Kirkman-Brown
BIRMINGHAM RESEARCH & DEVELOPMENT LTD
16/10/06 → 15/10/07
Project: Industry
BBSRC - CASE Award Insulin sensitivity in muscle and adipose: Glucocorticoids, pre-receptor hormone metabolism and tissue specific cross-talk
ASTRA ZENECA UK LIMITED
1/10/06 → 30/09/09
Project: Industry
Birmingham Interdisciplinary Bridging - Dr J Kirkman-Brown
MEDICAL RESEARCH COUNCIL
1/10/06 → 30/06/07
Project: Research Councils
Corticosteroid Hormone Action in Cardiomyocytes - Impact on Heart Failure
MEDICAL RESEARCH COUNCIL
1/10/06 → 30/09/09
Project: Research Councils
Mechanisms Responsible for Cardiac and Skeletal Muscle Energetic Impairment in Type 1 Diabetes
Michael Frenneaux, Martin Stevens & Anton Wagenmakers
BRITISH HEART FOUNDATION
1/10/06 → 31/03/09
Project: Research
Selective Inhibition of 11beta-Hydroxysteroid Dehydrogenase Type 1: A Novel Treatment for the Metabolic Syndrome
Jeremy Tomlinson & Paul Stewart
MEDICAL RESEARCH COUNCIL
1/10/06 → 30/09/09
Project: Research Councils
Wellcome Trust - Dr M L Read - Complete work required for a programme grant application by Professor Logan; Completion of work that will lead to publication of five papers
THE WELLCOME TRUST
1/10/06 → 31/03/07
Project: Research
The Role of Monocarboxylate Transporter 8 (MCT8) in Human Fetal Brain Development and the Effects of Intrauterine Growth Restriction
Shiaoyng Chan, Jayne Franklyn, Mark Kilby, Ann Logan & Christopher McCabe
THE HEALTH FOUNDATION
15/09/06 → 30/06/14
Project: Research
Securin and Separase Expression and Effects in Intrauterine Growth Restricted (IUGR) Fetal Brains
BIRMINGHAM CHILDRENS HOSPITAL RESEARCH FOUNDATION
23/08/06 → 22/08/07
Project: Research
Fluid Mechanics and the Human Male Gamete - Novel Physiological Modelling of Sperm Motility and Female Tract Interaction
David Smith, Jackson Kirkman-Brown, John Blake & Christopher Barratt
MEDICAL RESEARCH COUNCIL
1/08/06 → 31/01/10
Project: Research Councils
Genetics of Nicotinamide N-methyltransferase and Parkinson's Disease
David Ramsden & Adrian Williams
THE PARKINSONS DISEASE SOCIETY
1/06/06 → 30/09/06
Project: Research
VIP Development Award - Mr DJ Smith
John Blake & Jackson Kirkman-Brown
THE WELLCOME TRUST
1/04/06 → 30/09/06
Project: Research
Epigenetic Regulation of Nutrient Sensing in the Prostate
BIOTECHNOLOGY & BIOLOGICAL SCIENCES
1/02/06 → 31/01/09
Project: Research
How Do Regulatory T Cells Influence Materno-Fetal Tolerance?
David Sansom, Mark Kilby & Lucy Walker
MEDICAL RESEARCH COUNCIL
1/01/06 → 31/12/09
Project: Research Councils
GMP Facilities for IVF
Sarah Conner, Jackson Kirkman-Brown &
MEDICAL RESEARCH COUNCIL
7/11/05 → 6/10/09
Project: Research Councils
Heritability of Infancy Growth: The Birmingham Prospective Twin Study
Maurice Zeegers, Andrew Ewer, Timothy Barrett & Khalid Khan
BIRMINGHAM CHILDRENS HOSPITAL RESEARCH FOUNDATION
3/10/05 → 2/10/11
Project: Research
Prediction of Mortality in Overt and Subclinical Hyperthyroidism
BRITISH THYROID FOUNDATION
3/10/05 → 2/06/09
Project: Research
Predicting Clinical Outcome from Genotype: A Molecular Diagnostic Service for Paediatric Genetic Disease
Timothy Barrett, , &
BIRMINGHAM CHILDRENS HOSPITAL RESEARCH FOUNDATION
1/10/05 → 31/12/08
Project: Research
A Multi-Centre Randomised Controlled Trial Comparing Intra-Uterine Vesico-Amniotic Shunting vs Not Shunting in the Treatment of Congenital Bladder Outflow Obstruction
Mark Kilby, Jane Daniels, Richard Gray, Khalid Khan & David Somerset
WELLBEING OF WOMEN
1/09/05 → 31/10/12
Project: Research
A randomised controlled trial evaluationg the efficacy of vesico amniotic shunting in fetuses with bladder outflow obstruction effects on morbidity & survival
BIRMINGHAM WOMENS NHS TRUST
1/09/05 → 31/12/09
Project: Research
The Value of Predicting Restriction of Fetal Growth and Compromise of its Wellbeing: Systematic Quantitative Overviews (Meta-Analysis) of Test Accuracy Literature
BIRMINGHAM WOMENS NHS TRUST, WELLBEING OF WOMEN
22/08/05 → 31/07/10
Project: Research
Taurine and Diabetic Painful Neuropathy
NATIONAL INSTITUTE OF HEALTH, USA, UHB CHARITABLE FUNDS, BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/07/05 → 30/09/12
Project: Research
The Role of Monocarboxylate Transporter 8 in N-Tera-2 Cell Proliferation and Neurodifferentiation
MASON MEDICAL RESEARCH FOUNDATION
12/05/05 → 11/05/07
Project: Research
Lilly Diabetes Clinical Research Grants 2005
LILLY RESEARCH CENTRE LIMITED
2/05/05 → 1/05/10
Project: Industry
PARP Activation and Diabetic Neuropathic Pain
PENNINGTON BIOMEDICAL RESEARCH CENTER
1/02/05 → 1/01/08
Project: Research
11th Annual Congress of the European Society of Gene Therapy
THE ROYAL SOCIETY
1/11/04 → 30/11/04
Project: Research
PTTG and the Sodium Iodide Symporter in Thyroid Cancer
Christopher McCabe, Kristien Boelaert & Jayne Franklyn
UHB CHARITABLE FUNDS
4/10/04 → 3/10/07
Project: Research
Hexose-6-Phosphate Dehydrogenase, 11B-Hydroxysteroid Dehydrogenase Type 1 in Obesity and Insulin Resistance
Jeremy Tomlinson & Paul Stewart
THE WELLCOME TRUST
1/10/04 → 31/12/09
Project: Research
Pituitary Radiotherapy as a Risk Factor for Cerebrovascular Disease and Neurocognitive Dysfunction
UHB CHARITABLE FUNDS
1/10/04 → 31/07/07
Project: Research