Metabolism and Systems Research
Organisational unit: School
Research Projects
An assessment of the contribution of the MHC II genes to multiple sclerosis in caucasians and other racial groups
NHS EXECUTIVE
1/08/92 → 28/02/93
Project: Research
Assessment of the contribution of the DQ and other MHC genes to susceptibility to insulin dependant diabetes using.......
BRITISH DIABETIC ASSOCIATION
1/08/92 → 31/08/92
Project: Research
Certification campaign for the analysis of thyroxine in three lyophilized batches.
EUROPEAN COMMISSION
1/08/92 → 31/12/92
Project: EU
DNA hybridisation analysis of the HLA-D region genes in insulin-dependent diabetes mellitus
THE WELLCOME TRUST
1/08/92 → 31/07/93
Project: Research
DO THE DQ MOLECULES DQW6 & DQWL.18 DIRECTLY PROTECT AGAINSTINSULIN DEPENDANT DIABETES MELLITUS
BRITISH DIABETIC ASSOCIATION
1/08/92 → 12/07/94
Project: Research
The Role Of HLA-DQ Expression In Susceptibility To Insulin- Dependent Diabetes
JUVENILE DIABETES FOUNDATION INTERNATIONAL
1/08/92 → 30/09/93
Project: Research
Thyroid Hormone Receptor Expression And Function In TheHuman Liver
MEDICAL RESEARCH COUNCIL
1/08/92 → 5/05/95
Project: Research Councils
Training Fellowship Dr Davies-Deiodinase enzyme & T ReceptorExpression:effects on Thyroid Status
MEDICAL RESEARCH COUNCIL
1/08/92 → 31/07/95
Project: Research Councils
R.D.Lawrence Fellowship - Glucokinase Genetics in Type 2Diabetes Mellitus
BRITISH DIABETIC ASSOCIATION
1/09/92 → 31/05/93
Project: Research
Assessment of Contribution of the DQ & other MHC Genes toSuceptibility to insulin dependent Diabetes trans-racial app
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/10/92 → 31/12/93
Project: Research
Diabetes Research Fund Clinical Fellowship
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/06/93 → 30/09/02
Project: Research
Mapping & Characterization of Susceptibilty Genes in Multi -Factorial Diseases
THE WELLCOME TRUST
1/06/93 → 30/06/96
Project: Research
Assessment of Contribution of DQ & Other MCH Genes toSusceptibility Insulin Dependent Using Trans Racial Approach
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/07/93 → 30/06/94
Project: Research
Determination of the role of the transporter associated withantigen processing TAP genes in susceptibility insulin depen
Tony Barnett, Catherine Mijovic & Michael Sheppard
BRITISH DIABETIC ASSOCIATION
1/08/93 → 31/01/96
Project: Research
Role of Proto-Oncogenes in the Control of Myocardial Growth
Michael Gammage & Jayne Franklyn
BRITISH HEART FOUNDATION
1/10/93 → 6/11/95
Project: Research
Regulation of TSH subunit gene expression in human pituitarytumours
UHB CHARITABLE FUNDS
1/02/94 → 25/08/95
Project: Research
The clinical impact of thyroid dysfunction
MEDICAL RESEARCH COUNCIL
1/02/94 → 30/01/95
Project: Research Councils
The long term consequences of treatment for thyroid disease
THE BUPA MEDICAL FOUNDATION LIMITED - BUPA001
1/02/94 → 31/01/97
Project: Research
A Comparison Of Lacidipine Versus Ace Inhibition InHypertensive Diabetics With Established Nephropathy
BOEHRINGER INGELHEIM LTD
1/07/94 → 30/07/96
Project: Industry
Sheldon Fellowship: The Clinical and Molecular BiologicalCharacterisation of Diabetes associated with Mitochondrial m
NHS EXECUTIVE
1/07/94 → 30/06/97
Project: Research
Do the DQ molecules DQw6 and DQw1.18 directly protectagainst insulin dependent diabetes mellitus?
Tony Barnett, Catherine Mijovic & Michael Sheppard
BRITISH DIABETIC ASSOCIATION
13/07/94 → 30/04/97
Project: Research
Trans-racial analysis of HLA class II regulatory region polymorphism
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/10/94 → 31/10/97
Project: Research
Long-Term Morbidity & Mortality in patients treated forThyroid Disease
Jayne Franklyn & Lillian Somervaille
UHB CHARITABLE FUNDS
1/01/95 → 31/12/95
Project: Research
Application for partial funding of an Applied Biosystemsmodel 373 Sequencer to faciliate semi-automated linkage and
MEDICAL RESEARCH COUNCIL
1/04/95 → 31/07/95
Project: Research Councils
Effects of Vitamin D Receptor Gene Polymorphisms on VDR Expression and Cellular Responses to Calcitriol
Martin Hewison & Michael Sheppard
NHS EXECUTIVE
1/07/95 → 30/06/97
Project: Research
Effects of Vitamin D Receptor Gene Polymorphisms on VDRExpression and Cellular Responses to Calcitriol.
Martin Hewison & Michael Sheppard
NHS EXECUTIVE
1/07/95 → 31/12/98
Project: Research
Studies of Vitamin D receptor expression in immune cells
MEDICAL RESEARCH COUNCIL
1/08/95 → 31/07/96
Project: Research Councils
Thyroid and gonadal steroid hormone receptor expression andfunction in human pituitary tumours
MEDICAL RESEARCH COUNCIL
1/09/95 → 31/08/98
Project: Research Councils
The Molecular Biology of Thiol Methyltransferase: A Detoxification Enzyme of Potential Relevance to the Aetiology of Idi
David Nicholl, David Ramsden & Adrian Williams
NHS EXECUTIVE
1/10/95 → 30/09/97
Project: Research
Nuetrophil Activation in the Feto-placental Circulation ofthe Growth Retarded Fetus
BIRMINGHAM WOMENS NHS TRUST
1/12/95 → 31/03/97
Project: Research
Effects of calcitriol on psoriasis: analysis of differentialgene expression
THE PSORIASIS ASSOCIATION
1/01/96 → 31/12/97
Project: Research
Hormone receptor expression and function in human pituitarytumours
NHS EXECUTIVE
1/02/96 → 31/01/98
Project: Research
Cloning and characterisation of 25-hydroxyvitamin D31X-hydroxylase in human kidney cells
MEDICAL RESEARCH COUNCIL
1/04/96 → 30/09/99
Project: Research Councils
Bone Metabolism of Sex Steroids and Corticosteroids:Autocrine Regulation of Bone Remodelling
UHB CHARITABLE FUNDS
13/05/96 → 31/12/97
Project: Research
A Comparison Of Lacidipine Versus ACE Inhibition InHypertensive Diabetics With Established Nephropathy.
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/07/96 → 31/03/99
Project: Research
Mapping & Characterisation Of Susceptibility Genes InMultifactorial Diseases.
BRITISH DIABETIC ASSOCIATION
1/07/96 → 31/12/96
Project: Research
Thyroid Receptor Isoforms and the Differential MuscularDevelopment of Ducks & Geese
LEVERHULME TRUST
1/07/96 → 30/06/98
Project: Research
Genetic Susceptibility To The Development Of AutoimmuneDiseases
Stephen Bain, Tony Barnett, Jayne Franklyn & Stephen Gough
THE WELLCOME TRUST
1/08/96 → 31/03/00
Project: Research
The Genetics Of Autoimmune Thyroid Disease
Stephen Gough & Jayne Franklyn
UHB CHARITABLE FUNDS
1/08/96 → 31/05/99
Project: Research
The Genetics Of Complex Disease
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/09/96 → 30/06/01
Project: Research
Nicotinamide-N-Methyltransferase: A Genetic Component in the Aetiology of Idiopathic Parkinsons Disease.
David Ramsden, Peter Barber, Rosemary Waring & Adrian Williams
THE PARKINSONS DISEASE SOCIETY
1/10/96 → 31/12/00
Project: Research
Sex Steroids Cortisol And Central Obesity.
Sudhesh Kumar, Tony Barnett, Margaret Eggo & Paul Stewart
BRITISH DIABETIC ASSOCIATION
1/10/96 → 30/09/98
Project: Research
Aberrant Thyroid Growth In Man The Role Of FibroblastGrowth Factors 1 And 2.
Margaret Eggo, Jayne Franklyn & Ann Logan
THE WELLCOME TRUST
1/01/97 → 30/04/02
Project: Research
Prenatal Programming Of Lipoprotein Metabolism And EffectsOn Vascular Adhesion Molecule Expression In Intrauterine ...
TOMMY'S
1/01/97 → 31/12/04
Project: Research
Do the DQ molecules Dqw6 and Dqw1.18 directly protectagainst insulin dependent diabetes mellitus
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/05/97 → 31/08/99
Project: Research
Central Obesity And The Metabolic Syndrome:Role Of SexSteroids Cortisol And Their Metabolism By Adipocytes
THE WELLCOME TRUST
1/09/97 → 31/08/98
Project: Research
Investigation into Type 1 Diabetes
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/01/98 → 30/09/00
Project: Research
The Golden Years Project
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/01/98 → 31/03/02
Project: Research
Genetic Susceptibility to the Development of AutoimmuneDiseases
Jayne Franklyn, Stephen Bain, Tony Barnett & Stephen Gough
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/04/98 → 30/09/99
Project: Research
Expression of Vitamin D Polymorphisms Type 1 diabites
THE WELLCOME TRUST
6/07/98 → 28/08/98
Project: Research
Thyroid Hormone Receptor Expression in Human Fetal Central Nervous System: the Effects of Intrauterine Growth Restriction
UHB CHARITABLE FUNDS
1/09/98 → 31/10/01
Project: Research
Nephropathy Studies (J Rippin)
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
15/09/98 → 30/06/02
Project: Research
Society for Endocrinology Prize Studentship
SOCIETY FOR ENDOCRINOLOGY
1/10/98 → 30/09/01
Project: Research
The Expression of Placental 11beta Hydroxysteroid Dehydrogenase Enzymes in Human Intrauterine Growth Restriction
ACTION RES. FOR THE CRIPPLED CHILD
1/10/98 → 31/03/01
Project: Research
Understanding Childhood Diabetes: Positional Cloning of the Gene for an Inherited Diabetic Syndrome (Wolfram/DIDMOAD).
Timothy Barrett, Farida Latif &
SPORT AIDING MEDICAL RESEARCH FOR KIDS
1/10/98 → 31/10/02
Project: Research
Metabolism of Precursor Sex Steroids by 17-B Hydroxysteroid Dehydrogenase in Adipose Tissue and its Role in Disease States
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/11/98 → 31/10/01
Project: Research
Identification of the Structural Characterustics of the HLA-DQ6 Molecule which Confer Protection Against IDDM
Ann (Wilson) Kelly & Tony Barnett
LILLY RESEARCH CENTRE LIMITED
1/12/98 → 30/11/00
Project: Industry
Thyroid Hormone Receptor Expression and Function in non Functioning Pituitary Tumours
Michael Sheppard, Jayne Franklyn & Neil Gittoes
MEDICAL RESEARCH COUNCIL
1/12/98 → 31/10/04
Project: Research Councils
Functional Characterisation and Cellular Expression OfHepatocyte Growth Factor And It's Interaction With Other ...
BRITISH HEART FOUNDATION
4/01/99 → 3/05/03
Project: Research
Adipose Tissue Insulin Resistance in the Pathogenesis of the Chronic Cardiovascular Risk Factor Syndrome
Sudhesh Kumar, Tony Barnett & Margaret Eggo
NHS EXECUTIVE
1/02/99 → 31/01/01
Project: Research
Elucidating the Structural Requirments for Natural HLA-DQ6-mediated Protection Against Type 1 Diabetes : A Prerequisite for the Design of Novel Therapeutic Stategies
Tony Barnett & Ann (Wilson) Kelly
BRITISH DIABETIC ASSOCIATION
1/04/99 → 31/03/02
Project: Research
Intrauterine Growth Restriction and Subsequent Neonatal Gastro - Intestinal Function
CHILDRENS RESEARCH FUND
1/05/99 → 31/08/02
Project: Research
Bioscam 200 Imaging Scanner - Automatic Thin Layer Chromatography Analyser
Martin Hewison, Sudhesh Kumar & Joanne Mountford
THE WELLCOME TRUST
1/07/99 → 30/06/02
Project: Research
Prevalence and Aetiology of Osteporosis in Children and Young Adults with B Thalassaemia
SPORT AIDING MEDICAL RESEARCH FOR KIDS
1/09/99 → 31/08/01
Project: Research
Molecular Mechanisms for the Potentiation of differentiation Theraphy in Myeloid leukaemias
Martin Hewison & Christopher Bunce
BLOODWISE
1/10/99 → 30/09/01
Project: Research
Adipose Tissue Insulin Resistance and the Effect of Rosiglitazone
SMITH KLINE BEECHAM PHARMACEUTICALS R & D
1/11/99 → 31/05/01
Project: Industry
A Collaboration study to identfy Susceptibility in pre-eclampsia (BHF project sub -contract with Notts Uni.)
BRITISH HEART FOUNDATION
1/12/99 → 31/05/03
Project: Research
The CTLA-4/CD28 Gene region on Chromosome 2q33 and the Development of Auto-Immune Thyroid Disease
Stephen Gough, Jayne Franklyn & Peter Lane
THE WELLCOME TRUST
1/12/99 → 30/04/03
Project: Research
Hormonal substrate support in coronary artery surgery inotropy without increased oxygen consumption
, Abdul-Hakam Al-Khalidi, John Coote, Jayne Franklyn & Jon Townend
BRITISH HEART FOUNDATION
1/01/00 → 25/07/04
Project: Research
N-Methylpyridines in Parkinsons Disease.
THE PARKINSONS DISEASE SOCIETY
1/04/00 → 31/03/01
Project: Research
Investigation of the Genetic Susceptibility to Diabetic Nephropathy in Type 1 Diabetes Mellitus
BRITISH DIABETIC ASSOCIATION
4/09/00 → 30/04/03
Project: Research
Thyroid Status and Intrauterine Growth Restriction
MEDICAL RESEARCH COUNCIL
1/10/00 → 30/09/03
Project: Research Councils
Regulation and Expression of 11 Beta-Hydroxysteroid Dehydrogenase Type 1 in Human Adipose Tissue
MEDICAL RESEARCH COUNCIL
2/10/00 → 1/10/03
Project: Research Councils
Systematic quantitative overviews (meta-analyses) of the literature to determine the value of diagnostic tests for predicting preterm Birth
WELLBEING OF WOMEN
16/11/00 → 15/11/02
Project: Research
Pituitary Tumour Transforming Gene (PTTG), PTTG Binding Factor (PBF) and Related Growth Factor Expression in Thyroid Cancer
BRITISH THYROID FOUNDATION
1/12/00 → 30/11/01
Project: Research
Glucocorticoid Metabolism in Osteoblasts: Autocrine Regulation of Steroid Hormone Action in Bone
NHS EXECUTIVE
1/01/01 → 30/06/03
Project: Research
Psychosocial factors & wellbeing in women receving a detailed ultrasound scan
BIRMINGHAM WOMENS NHS TRUST
1/01/01 → 31/12/04
Project: Research
The Co-Expression of Thyroid Receptor Isoforms and Neuronal Cytoskeletal Proteins in the Central Nervous System of Growth Restricted Fetal Guinea Pigs
MASON MEDICAL RESEARCH FOUNDATION
1/01/01 → 31/12/01
Project: Research
Pituitary tumour transforming gene (PTTG) expression and function in pituitary tumours.
Christopher McCabe & Jayne Franklyn
UHB CHARITABLE FUNDS
1/02/01 → 31/01/04
Project: Research
Does Paternal Mitochondrial DNA Regulate Trophoblast Cell Development?
UHB CHARITABLE FUNDS
2/02/01 → 30/09/02
Project: Research
Expression of 1-Hydroxylase in Human Islet Cells: A Role for Local Activation of Vitamin D in the Pancreas
BRITISH DIABETIC ASSOCIATION
1/03/01 → 31/08/01
Project: Research
1,25-Dihydroxyvitamin D3, HOXA10 and Fetal Implantation: A Novel Role for Extra-Renal Expression of 1Alpha-Hydroxylase
BIOTECHNOLOGY & BIOLOGICAL SCIENCES
5/03/01 → 30/09/04
Project: Research Councils
Thyroid Dysfunction in the Elderly: Quantifying the Association Between Sub-Clinical Disease and (i) Atrial Fibrillation (and thus stroke) (ii) Depression and (iii) Cognitive Dysfunction.
Jim Parle, Jayne Franklyn, Michael Gammage, Caroline Heath, Richard Hobbs, Helen Pattison, Andrea Roalfe, Michael Sheppard & Sue Wilson
THE HEALTH FOUNDATION
15/03/01 → 15/12/05
Project: Research
A Randomised Controlled Trial of the Effects of Antioxidant & Folinic Acid Supplementation on the Mental Development, Growth & Health of Children with Downs Syndrome
DOWNS SYNDROME ASSOCIATION
1/10/01 → 31/12/05
Project: Research
Pre-receptor Regulation of Glucocorticoids and the Control of Pituitary Cell Proliferation: A Novel Target for Tumour Therapy
UHB CHARITABLE FUNDS
1/10/01 → 29/02/04
Project: Research
Pituitary Tumor Transforming Gene (PTTG) - Mechanisms of Signalling and Action
SOCIETY FOR ENDOCRINOLOGY
1/12/01 → 30/11/03
Project: Research
Functional Role of Pituitary Tumor Transforming Gene (PTTG) and Related Growth Factors in Endocrine Cell Growth and Function
Jayne Franklyn & Kristien Boelaert
THE WELLCOME TRUST
1/03/02 → 31/03/04
Project: Research
A Randomised Controlled Trial of Laparoscopic Utero-sacral Nerve Ablation (LUNA) in Chronic Pelvic Pain
Khalid Khan, Richard Gray, Jane Daniels, Janesh Gupta & Richard Lilford
WELLBEING OF WOMEN, BIRMINGHAM WOMENS NHS TRUST
1/04/02 → 31/12/10
Project: Research
Elucidating the structual requirements for natural HLA-DQ6 mediated protection against type 1 Diabetes
BIRMINGHAM HEARTLANDS AND SOLIHULL NHS TRUST
1/04/02 → 31/12/04
Project: Research