Healthcare Technologies Institute

2024

Expression of E-cadherin by CD8⁺ T cells promotes their invasion into biliary epithelial cells

Davies, S. P., Ronca, V., Wootton, G. E., Krajewska, N. M., Bozward, A. G., Fiancette, R., Patten, D. A., Yankouskaya, K., Reynolds, G. M., Pat, S., Osei-Bordom, D. C., Richardson, N., Grover, L. M., Weston, C. J. & Oo, Y. H., 29 Jan 2024, In: Nature Communications. 15, 1, 22 p., 853.

Research output: Contribution to journal › Article › peer-review

Open Access

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14 Downloads (Pure)

PressureCap: An endoscopic sensor capsule for real-time gastrointestinal pressure monitoring

Mitrakos, V., Cummins, G., Tauber, F. J., Cox, B. F., Pavaluri, S. K., Wood, G. S., Potter, M. A., Clutton, E., Cochran, S., Speck, T., Hands, P. J. W. & Desmulliez, M. P. Y., 19 Mar 2024, (E-pub ahead of print) In: Device. 100325.

Research output: Contribution to journal › Article › peer-review

Open Access

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2 Downloads (Pure)

Vibrational spectroscopic profiling of biomolecular interactions between oak powdery mildew and oak leaves

Clark, K. R. & Goldberg Oppenheimer, P., 3 Jan 2024, In: Soft Matter. 20, 5, p. 959-970 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2 Downloads (Pure)

2023

Achieving net-zero in the dry eye disease care pathway

Latham, S., Williams, R., Grover, L. & Rauz, S., 13 Nov 2023, In: Eye. 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

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1 Downloads (Pure)

Chelating silica nanoparticles for efficient antibiotic delivery and particle imaging in Gram-negative bacteria

Muguruza, A. R., di Maio, A., Hodges, N. J., Blair, J. & Pikramenou, Z., 7 May 2023, In: Nanoscale Advances. 5, 9, p. 2453-2461 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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44 Downloads (Pure)

Cobalt containing glass fibres and their synergistic effect on the HIF-1 pathway for wound healing applications

Solanki, A. K., Autefage, H., Rodriguez-Romero, A., Agarwal, S., Penide, J., Mahat, M., Whittaker, T., Nommeots-Nomm, A., Littmann, E., Payne, D. J., Metcalfe, A. D., Quintero, F., Pou, J., Stevens, M. M. & Jones, J. R., 10 Mar 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 15 p., 1125060.

Research output: Contribution to journal › Article › peer-review

Open Access

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Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies

Khan, A. O., Rodriguez-Romera, A., Reyat, J. S., Olijnik, A. A., Colombo, M., Wang, G., Wen, W. X., Sousos, N., Murphy, L. C., Grygielska, B., Perrella, G., Mahony, C. B., Ling, R. E., Elliott, N. E., Karali, C. S., Stone, A. P., Kemble, S., Cutler, E. A., Fielding, A. K., Croft, A. P., & 7 othersBassett, D., Poologasundarampillai, G., Roy, A., Gooding, S., Rayes, J., Machlus, K. R. & Psaila, B., 6 Feb 2023, In: Cancer Discovery. 13, 2, p. 364-385 22 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

54 Downloads (Pure)

Hybrid use of Raman spectroscopy and artificial neural networks to discriminate Mycobacterium bovis BCG and other Mycobacteriales

Macgregor-Fairlie, M., De Gomes, P., Weston, D., Rickard, J. J. S. & Goldberg Oppenheimer, P., 11 Dec 2023, In: PLoS ONE. 18, 12, e0293093.

Research output: Contribution to journal › Article › peer-review

Open Access

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13 Downloads (Pure)

Hydrogels and Bioprinting in Bone Tissue Engineering: Creating Artificial Stem-Cell Niches for In Vitro Models

Lewns, F. K., Tsigkou, O., Cox, L. R., Wildman, R. D., Grover, L. M. & Poologasundarampillai, G., 23 Apr 2023, (E-pub ahead of print) In: Advanced Materials. e2301670.

Research output: Contribution to journal › Review article › peer-review

Open Access

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12 Downloads (Pure)

Space habitats for bioengineering and surgical repair: addressing the requirement for reconstructive and research tissues during deep-space missions

Iordachescu, A., Eisenstein, N. & Appleby-Thomas, G., 25 Mar 2023, In: Nature NPJ Microgravity. 9, 1, 14 p., 23.

Research output: Contribution to journal › Article › peer-review

Open Access

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109 Downloads (Pure)

2022

Can We Structure Biomaterials to Spray Well Whilst Maintaining Functionality?

Moakes, R. J. A., Grover, L. M. & Robinson, T. E., 20 Dec 2022, In: Bioengineering (Basel, Switzerland). 10, 1, 15 p., 3.

Research output: Contribution to journal › Review article › peer-review

Open Access

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17 Downloads (Pure)

Development of Ni-base metal matrix composites by powder metallurgy hot isostatic pressing for space applications

Sergi, A., Khan, R. H. U., Irukuvarghula, S., Meisnar, M., Makaya, A. & Attallah, M. M., Feb 2022, In: Advanced Powder Technology. 33, 2, 103411.

Research output: Contribution to journal › Article › peer-review

Open Access

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66 Downloads (Pure)

Directional control of neurite outgrowth: emerging technologies for Parkinson's disease using magnetic nanoparticles and magnetic field gradients

Dhillon, K., Aizel, K., Broomhall, T. J., Secret, E., Goodman, T., Rotherham, M., Telling, N., Siaugue, J. M., Ménager, C., Fresnais, J., Coppey, M., El Haj, A. J. & Gates, M. A., Nov 2022, In: Journal of the Royal Society, Interface. 19, 196, 20220576.

Research output: Contribution to journal › Article › peer-review

Open Access

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31 Downloads (Pure)

Emerging therapies and their delivery for treating age-related macular degeneration

Thomas, C. N., Sim, D. A., Lee, W. H., Alfahad, N., Dick, A. D., Denniston, A. & Hill, L. J., May 2022, In: British Journal of Pharmacology. 179, 9, p. 1908-1937 30 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

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225 Downloads (Pure)

Magnetic Nanoparticle-Mediated Orientation of Collagen Hydrogels for Engineering of Tendon-Mimetic Constructs

Wright, A. L., Righelli, L., Broomhall, T. J., Lamont, H. C. & El Haj, A. J., 17 Mar 2022, In: Frontiers in Bioengineering and Biotechnology. 10, 797437.

Research output: Contribution to journal › Article › peer-review

Open Access

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40 Downloads (Pure)

Microstructure, tensile properties of SLMed TNT5Zr-0.2O alloys without/with keyholes produced by different Post-processing treatments

Kong, W., Shi, Q., Cox, S. C., Kuang, M. & Attallah, M. M., 15 Feb 2022, In: Materials Letters. 309, 131448.

Research output: Contribution to journal › Article › peer-review

Open Access

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27 Downloads (Pure)

Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation

Wu, M., Hill, L. J., Downie, L. E. & Chinnery, H. R., 19 Jul 2022, (E-pub ahead of print) In: Progress in Retinal and Eye Research. 101105.

Research output: Contribution to journal › Review article › peer-review

Open Access

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8 Downloads (Pure)

Optimisation of single contour strategy in selective laser melting of Ti-6Al-4V lattices

Cao, X., Carter, L., Villapun, V. M., Cantaboni, F., De Sio, G., Lowther, M., Louth, S., Grover, L., Ginestra, P. & Cox, S., 24 Feb 2022, (E-pub ahead of print) In: Rapid Prototyping Journal. 28, 5, p. 907-915

Research output: Contribution to journal › Article › peer-review

Open Access

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149 Downloads (Pure)

Photocurable GelMA adhesives for corneal perforations

Pires Moedas De Almeida Barros, I., Man, K., Robinson, T., Cox, S. & Ghag, A., 28 Jan 2022, In: Bioengineering. 9, 3, 53.

Research output: Contribution to journal › Article › peer-review

Open Access

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361 Downloads (Pure)

Self-assembled calcium pyrophosphate nanostructures for targeted molecular delivery

Bassett, D. C., Robinson, T. E., Hill, R. J., Grover, L. M. & Barralet, J. E., Sept 2022, In: Biomaterials advances. 140, 10 p., 213086.

Research output: Contribution to journal › Article › peer-review

Open Access

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43 Downloads (Pure)

2021

2D and 3D cartilage model platforms for drug evaluation and high-throughput screening assays

Foster, N., Hall, N. M. & El Haj, A., 16 Mar 2021, (E-pub ahead of print) In: Tissue Engineering Reviews: Part B.

Research output: Contribution to journal › Review article › peer-review

Open Access

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181 Downloads (Pure)

A feasible route for the design and manufacture of customised respiratory protection through digital facial capture

Carter, L., Reed, C., Morrell, A., Fong, A. K. H., Chowdhury, R., Miller, E., Alberini, F., Khambay, B., Anand, S., Grover, L., Coward, T., Addison, O. & Cox, S., 2 Nov 2021, In: Scientific Reports. 11, 1, 21449.

Research output: Contribution to journal › Article › peer-review

Open Access

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97 Downloads (Pure)

A hybrid reflection retrieval method for terahertz dielectric imaging of human bone

Freer, S., Sui, T., Hanham, S. M., Grover, L. & Navarro-Cia, M., 12 Jul 2021, In: Biomedical Optics Express. 12, 8, p. 4807-4820 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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131 Downloads (Pure)

A toolbox for generating scalable mitral valve morphometric models

de Oliveira, D. C., Espino, D. M., Deorsola, L., Mynard, J. P., Rajagopal, V., Buchan, K., Dawson, D. & Shepherd, D. E. T., Aug 2021, In: Computers in Biology and Medicine. 135, 104628.

Research output: Contribution to journal › Article › peer-review

Open Access

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76 Downloads (Pure)

Bioactive glasses and electrospun composites that release cobalt to stimulate the HIF pathway for wound healing applications

Solanki, A. K., Lali, F. V., Autefage, H., Agarwal, S., Nommeots-Nomm, A., Metcalfe, A. D., Stevens, M. M. & Jones, J. R., Dec 2021, In: Biomaterials research. 25, 1, 16 p., 1.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

138 Downloads (Pure)

Biofilm viability checker: an open-source tool for automated biofilm viability analysis from confocal microscopy images

Mountcastle, S., Vyas, N., Villapun, V. M., Cox, S., Jabbari, S., Sammons, R., Shelton, R., Walmsley, D. & Kuehne, S., 14 May 2021, In: npj Biofilms and Microbiomes. 7, 1, 12 p., 44.

Research output: Contribution to journal › Article › peer-review

Open Access

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200 Downloads (Pure)

Computational fluid dynamics of the right atrium: Assessment of modelling criteria for the evaluation of dialysis catheters

de Oliveira, D. C., Owen, D. G., Qian, S., Green, N. C., Espino, D. M. & Shepherd, D. E. T., 25 Feb 2021, In: PLoS ONE. 16, 2, e0247438.

Research output: Contribution to journal › Article › peer-review

Open Access

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Direct Immobilization of Engineered Nanobodies on Gold Sensors

Simões, B., Guedens, W. J., Keene, C., Kubiak-Ossowska, K., Mulheran, P., Kotowska, A. M., Scurr, D. J., Alexander, M. R., Broisat, A., Johnson, S., Muyldermans, S., Devoogdt, N., Adriaensens, P. & Mendes, P. M., 21 Apr 2021, In: ACS Applied Materials & Interfaces. 13, 15, p. 17353-17360 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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180 Downloads (Pure)

Elucidating the Influence of Electrical Potentials on the Formation of Charged Oligopeptide Self-Assembled Monolayers on Gold

Gibson, J. S. & Mendes, P. M., 3 Feb 2021, (E-pub ahead of print) In: ChemPhysChem. 22, 7, p. 684-692

Research output: Contribution to journal › Article › peer-review

Open Access

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121 Downloads (Pure)

Establishing the Bladder Cancer Research Centre at the University of Birmingham

Bryan, R. T., Arnold, R., Khanim, F. L., Shepherd, D. E., Patel, P. & Ward, D. G., Jun 2021, In: Nature Reviews Urology. 18, 6, p. 318-320 3 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

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75 Downloads (Pure)

Exploring the Formation of Calcium Orthophosphate‐Pyrophosphate Chemical Gardens

Hughes, E. A. B., Jones‐salkey, O., Forey, P., Chipara, M. & Grover, L. M., 22 Jan 2021, (E-pub ahead of print) In: ChemSystemsChem.

Research output: Contribution to journal › Article › peer-review

Open Access

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195 Downloads (Pure)

Formulation of a Composite Nasal Spray Enabling Enhanced Surface Coverage and Prophylaxis of SARS-COV-2

Moakes, R. J. A., Davies, S. P., Stamataki, Z. & Grover, L. M., 31 May 2021, (E-pub ahead of print) In: Advanced Materials. e2008304.

Research output: Contribution to journal › Article › peer-review

Open Access

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306 Downloads (Pure)

Formulation of a reactive oxygen producing calcium sulphate cement as an anti-bacterial hard tissue scaffold

Hall, T., Hughes, E., Sajjad, H., Kuehne, S., Grant, M., Grover, L. & Cox, S., 24 Feb 2021, In: Scientific Reports. 11, 1, 4491.

Research output: Contribution to journal › Article › peer-review

Open Access

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176 Downloads (Pure)

Förster resonance energy transfer nanoplatform based on recognition-induced fusion/fission of DNA mixed micelles for nucleic acid sensing

Vafaei, S., Allabush, F., Tabaei, S. R., Male, L., Dafforn, T. R., Tucker, J. H. R. & Mendes, P. M., 25 May 2021, In: ACS Nano. 15, 5, p. 8517-8524 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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130 Downloads (Pure)

ILB® resolves inflammatory scarring and promotes functional tissue repair

Hill, L. J., Botfield, H., Begum, G., Qureshi, O., Vigneswara, V., Masood, I., Barnes, N., Bruce, L. & Logan, A., Dec 2021, In: npj Regenerative Medicine. 6, 1, 9 p., 3.

Research output: Contribution to journal › Article › peer-review

Open Access

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187 Downloads (Pure)

Open Access

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47 Downloads (Pure)

Low Acyl Gellan as an Excipient to Improve the Sprayability and Mucoadhesion of Iota Carrageenan in a Nasal Spray to Prevent Infection With SARS-CoV-2

Robinson, T. E., Moakes, R. J. A. & Grover, L. M., 16 Jun 2021, In: Frontiers in Medical Technology. 3, 687681.

Research output: Contribution to journal › Article › peer-review

Open Access

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168 Downloads (Pure)

M13 bacteriophage: A nanotool for the fabrication of novel self-assembled nanostructures

Passaretti, P., 25 Oct 2021, University of Birmingham. 281 p.

Research output: Thesis › Doctoral Thesis

Open Access

Methods and Products

Fernandez-Trillo, F., Overton, T., Adoni, P. & Huneidi, O., 21 Oct 2021, Patent No. WO2021209765A2, 16 Apr 2021, Priority date 17 Apr 2021, Priority No. GB2005605.7

Research output: Patent

Quantification by luminescence tracking of red emissive gold nanoparticles in cells

Dosumu, A. N., Claire, S., Watson, L. S., Girio, P. M., Osborne, S. A. M., Pikramenou, Z. & Hodges, N. J., 22 Feb 2021, In: JACS Au. 1, 2, p. 174-186 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Quantitative evaluation of frequency domain measurements in high density diffuse optical tomography

Perkins, G., Eggebrecht, A. T. & Dehghani, H., 4 May 2021, In: Journal of Biomedical Optics. 26, 5, 18 p., 056001 .

Research output: Contribution to journal › Article › peer-review

Open Access

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Signal regression in frequency-domain diffuse optical tomography to remove superficial signal contamination

Veesa, J. D. & Dehghani, H., 31 Mar 2021, (E-pub ahead of print) In: Neurophotonics. 8, 1, 17 p., 015013.

Research output: Contribution to journal › Article › peer-review

Open Access

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Supramolecular Cylinders Target Bulge Structures in the 5' UTR of the RNA Genome of SARS-CoV-2 and Inhibit Viral Replication*

Melidis, L., Hill, H. J., Coltman, N. J., Davies, S. P., Winczura, K., Chauhan, T., Craig, J. S., Garai, A., Hooper, C. A. J., Egan, R. T., McKeating, J. A., Hodges, N. J., Stamataki, Z., Grzechnik, P. & Hannon, M. J., 29 Apr 2021, (E-pub ahead of print) In: Angewandte Chemie (International Edition) . 60, 33, p. 18144-18151

Research output: Contribution to journal › Article › peer-review

Open Access

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170 Downloads (Pure)

Surface finish of additively manufactured metals: biofilm formation and cellular attachment

Ginestra, P., Riva, L., Ceretti, E., Lobo, D., Mountcastle, S., Villapun, V., Cox, S., Grover, L., Attallah, M., Addison, O., Shepherd, D. & Webber, M., 12 Apr 2021, ESAFORM 2021 - 24th International Conference on Material Forming. PoPuPS (University of LiFge Library), 2089. (ESAFORM 2021 - 24th International Conference on Material Forming).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Open Access

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