Leukemia, 0887-6924

Journal

1 - 63 out of 63Page size: 100

Publications

  1. 2019
  2. Published

    Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma

    Lauren Lupino, Tracey Perry, Sandra Davies, Robert Hollows, Roy Bicknell, Wenbin Wei, Martin Rowe, Katerina Vrzalikova & 1 others, Paul Murray, Dec 2019, In: Leukemia. 33, 12, p. 2884-2897 14 p.

    Research output: Contribution to journal › Article › peer-review

  3. Published

    CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex

    Giacomo Volpe, Jon Frampton, Jul 2019, In: Leukemia. 33, p. 1608-1619 12 p.

    Research output: Contribution to journal › Article › peer-review

  4. 2018
  5. Published

    A comparison of FLAG-Ida and daunorubicin combined with clofarabine in high-risk acute myeloid leukaemia: data from the UK NCRI AML17 Trial

    Sylvie Freeman, 31 Dec 2018, In: Leukemia. 5 p.

    Research output: Contribution to journal › Article › peer-review

  6. Published

    Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma

    Pierre Cauchy, Salam Assi, Peter Cockerill & Conny Bonifer, 13 Dec 2018, In: Leukemia.

    Research output: Contribution to journal › Article › peer-review

  7. Published

    Characterisation of immunoparesis in newly diagnosed myeloma and its impact on progression-free and overall survival in both old and recent myeloma trials

    Jennifer Heaney, John Campbell, Alex Richter & Mark Drayson, Aug 2018, In: Leukemia. 32, 8, p. 1727–1738 12 p.

    Research output: Contribution to journal › Article › peer-review

  8. E-pub ahead of print

    The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia

    Pamela Kearns, 20 Mar 2018, In: Leukemia. 10 p.

    Research output: Contribution to journal › Article › peer-review

  9. 2017
  10. Published

    S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells

    Katerina Vrzalikova, Martina Vockerodt, Lauren Lupino, Eszter Nagy, Robert Hollows, Wenbin Wei & 2 others, & Paul Murray, 3 Oct 2017, In: Leukemia.

    Research output: Contribution to journal › Article › peer-review

  11. Published

    Expression of CD33 is a predictive factor for effect of gemtuzumab ozogamicin at different doses in adult acute myeloid leukaemia

    Naeem Khan, Robert Hills & Sylvie Freeman, 31 May 2017, In: Leukemia. 31, 5, p. 1059-1068

    Research output: Contribution to journal › Article › peer-review

  12. Published

    Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma

    Katherine Eales, Wenbin Wei, Sarah Essex, Andrew Filer, Paul Moss, Dickens Pratt, Clare Davies & Daniel Tennant, Feb 2017, In: Leukemia. 31, 2, p. 373-381

    Research output: Contribution to journal › Article › peer-review

  13. 2016
  14. E-pub ahead of print

    Transcriptional regulation of SPROUTY 2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3

    Mary Clarke, Giacomo Volpe, Lozan Sheriff, Carl Ward, Wenbin Wei, Stephanie Dumon, Paloma Garcia & Jon Frampton, 8 Nov 2016, In: Leukemia.

    Research output: Contribution to journal › Article › peer-review

  15. E-pub ahead of print

    A comparison of clofarabine with ara-C, each in combination with daunorubicin as induction treatment in older patients with acute myeloid leukaemia

    Robert Hills, Sylvie Freeman, 30 Sep 2016, In: Leukemia.

    Research output: Contribution to journal › Article › peer-review

  16. Published

    Metabolic plasticity in CLL: adaptation to the hypoxic niche

    Katarzyna Koczula, Christian Ludwig, Leroy Cronin, Dickens Pratt, Helen Parry, Daniel Tennant, Mark Drayson, Christopher Bunce, Farhat Khanim & Ulrich Guenther, Jan 2016, In: Leukemia. 30, 1, p. 65–73 9 p.

    Research output: Contribution to journal › Article › peer-review

  17. Published

    The leukemia-associated RUNX1/ETO oncoprotein confers a mutator phenotype

    Anetta Ptasinska, Salam Assi, Conny Bonifer & Jeffery Allan, Jan 2016, In: Leukemia. 30

    Research output: Contribution to journal › Article › peer-review

  18. 2015
  19. E-pub ahead of print

    UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO

    Salam Assi, Anetta Ptasinska, Conny Bonifer, 1 Dec 2015, In: Leukemia.

    Research output: Contribution to journal › Article › peer-review

  20. Published

    Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial

    Alan Parker, Tony Gardiner, Zoe Davies, Tatjana Stankovic & 1 others, , 10 Aug 2015, In: Leukemia.

    Research output: Contribution to journal › Article › peer-review

  21. Published

    The impact of SF3B1 mutations in CLL on the DNA-damage response

    Ceri Oldreive, Tatjana Stankovic, May 2015, In: Leukemia. 29, 5, p. 1133-42 10 p.

    Research output: Contribution to journal › Article › peer-review

  22. Published

    Prognostic value of monitoring a candidate immunophenotypic leukaemic stem/progenitor cell population in patients allografted for acute myeloid leukaemia

    Aimee Jackson, Josephine Khan, Naeem Khan, Charles Craddock & Sylvie Freeman, Apr 2015, In: Leukemia. 29, p. 988-991

    Research output: Contribution to journal › Article › peer-review

  23. Published

    Acquired Isodisomy on Chromosome 13 at diagnosis results in impaired overall survival in Patients with FLT3-ITD mutant Acute Myeloid Leukaemia

    Justin Loke, Kristian Brock, Paul Ferguson, Charles Craddock, Michael Griffiths & Manoj Raghavan, 2015, In: Leukemia. 29, 12, p. 2404-2407

    Research output: Contribution to journal › Article › peer-review

  24. Published

    Outcome of allogeneic hematopoietic stem-cell transplantation for adult patients with AML and 11q23/MLL rearrangement (MLL -r AML)

    Charles Craddock, 2015, In: Leukemia.

    Research output: Contribution to journal › Article › peer-review

  25. 2014
  26. Published

    A comparative assessment of the curative potential of reduced intensity allografts in acute myeloid leukaemia

    Charles Craddock, Jinlong Yin, Andy Howman, 7 Nov 2014, In: Leukemia. 29, p. 1478–1484 6 p.

    Research output: Contribution to journal › Article › peer-review

  27. Published

    A multi-centre phase 2 study of azacitidine in chronic myelomonocytic leukaemia

    Pierre Cauchy, Peter Cockerill, Jul 2014, In: Leukemia. 28, 7, p. 1570-1572 3 p.

    Research output: Contribution to journal › Letter › peer-review

  28. Published

    Delineating MEIS1 cis-regulatory elements active in hematopoietic cells

    Conny Bonifer, Peter Cockerill, Feb 2014, In: Leukemia. 28, 2, p. 433-436 4 p.

    Research output: Contribution to journal › Letter › peer-review

  29. Published

    IMWG consensus on risk stratification in multiple myeloma

    Keith Wheatley, Feb 2014, In: Leukemia. 28, 2, p. 269-77 9 p.

    Research output: Contribution to journal › Article › peer-review

  30. 2013
  31. Published

    Novel therapies for children with acute myeloid leukaemia

    Pamela Kearns, 1 Jul 2013, In: Leukemia. 27, 7, p. 1451-1460 10 p.

    Research output: Contribution to journal › Article › peer-review

  32. Published

    C/EBPα and MYB regulate FLT3 expression in AML

    Giacomo Volpe, Paloma Garcia, Emilie Dasse, Laura O'Neill, Jon Frampton & Stephanie Dumon, 23 Jan 2013, In: Leukemia. 27, 7, p. 1487-1496 10 p.

    Research output: Contribution to journal › Article › peer-review

  33. Published

    The addition of gemtuzumab ozogamicin to low-dose Ara-C improves remission rate but does not significantly prolong survival in older patients with acute myeloid leukaemia: Results from the LRF AML14 and NCRI AML16 pick-a-winner comparison

    Robert Hills, Keith Wheatley, 1 Jan 2013, In: Leukemia. 27, 1, p. 75-81 7 p.

    Research output: Contribution to journal › Article › peer-review

  34. 2012
  35. Published

    Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

    Anetta Ptasinska, Salam Assi, Maarten Hoogenkamp, Pierre Cauchy, Peter Cockerill & Conny Bonifer, 1 Aug 2012, In: Leukemia. 26, 8, p. 1829-1841

    Research output: Contribution to journal › Article › peer-review

  36. Published

    Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia

    Jean-Baptiste Cazier, Jul 2012, In: Leukemia. 26, 7, p. 1564-75 12 p.

    Research output: Contribution to journal › Article › peer-review

  37. Published

    Extreme telomere erosion in ATM-mutated and 11q-deleted CLL patients is independent of disease stage

    Victoria Weston, Tatjana Stankovic, 1 Apr 2012, In: Leukemia. 26, 4, p. 826-830 5 p.

    Research output: Contribution to journal › Article

  38. Published

    Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: a multicenter international myeloma working group study

    Sudhesh Kumar & 6 others, & Keith Wheatley, Jan 2012, In: Leukemia. 26, 1, p. 149-57 9 p.

    Research output: Contribution to journal › Article › peer-review

  39. Published

    Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia

    Charles Craddock, Sylvie Freeman, Manoj Raghavan, Robert Hills, Toon Brookes, Mark Griffiths & 5 others, , 2012, In: Leukemia. 27, 5, p. 1028-1036 9 p.

    Research output: Contribution to journal › Article › peer-review

  40. Published

    MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia

    Stephanie Dumon, Sylvie Freeman, Ban Dawood, Lozan Sheriff, Maelle Lorvellec, Jon Frampton & Paloma Garcia, 2012, In: Leukemia. 27, 3, p. 661-670 10 p.

    Research output: Contribution to journal › Article › peer-review

  41. 2011
  42. Published

    The addition of arsenic trioxide to low-dose Ara-C in older patients with AML does not improve outcome

    Keith Wheatley, 1 Jul 2011, In: Leukemia. 25, 7, p. 1122-1127 6 p.

    Research output: Contribution to journal › Article

  43. Published

    Factors predicting outcome after unrelated donor stem cell transplantation in primary refractory acute myeloid leukaemia.

    Charles Craddock, 1 May 2011, In: Leukemia. 25, 5, p. 808-13 6 p.

    Research output: Contribution to journal › Article

  44. 2010
  45. Published

    Analysis of BCR–ABL1 tyrosine kinase domain mutational spectra in primitive chronic myeloid leukemia cells suggests a unique mutator phenotype

    Charles Craddock, Michael Griffiths, 1 Oct 2010, In: Leukemia. 24, 10, p. 1817-1821 5 p.

    Research output: Contribution to journal › Article

  46. Published

    The use of biochemical markers of bone remodeling in multiple myeloma: a report of the International Myeloma Working Group

    Keith Wheatley, Oct 2010, In: Leukemia. 24, 10, p. 1700-12 13 p.

    Research output: Contribution to journal › Article › peer-review

  47. Published

    Clinical significance of flowcytometric minimal residual disease detection in pediatric acute myeloid leukemia patients treated according to the DCOG ANLL97/MRC AML12 protocol

    Keith Wheatley, 1 Sep 2010, In: Leukemia. 24, 9, p. 1599-1606 8 p.

    Research output: Contribution to journal › Article

  48. Published

    Relationship between elevated immunoglobulin free light chain and the presence of IgH translocations in multiple myeloma

    Jo Bradwell, 1 Aug 2010, In: Leukemia. 24, 8, p. 1498-1505 8 p.

    Research output: Contribution to journal › Article

  49. Published

    Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management

    & 8 others, & Keith Wheatley, Jun 2010, In: Leukemia. 24, 6, p. 1121-7 7 p.

    Research output: Contribution to journal › Article › peer-review

  50. Published

    Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia

    & 2 others, Dickens Pratt, 1 Apr 2010, In: Leukemia. 24, 4, p. 877-881 5 p.

    Research output: Contribution to journal › Article

  51. 2009
  52. Published

    International Myeloma Working Group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation

    Sudhesh Kumar & 19 others, , Anthony Spencer & Keith Wheatley, Oct 2009, In: Leukemia. 23, 10, p. 1716-30 15 p.

    Research output: Contribution to journal › Article › peer-review

  53. Published

    International myeloma working group (IMWG) consensus statement and guidelines regarding the current status of stem cell collection and high-dose therapy for multiple myeloma and the role of plerixafor (AMD 3100)

    Sudhesh Kumar & 21 others, & Keith Wheatley, Oct 2009, In: Leukemia. 23, 10, p. 1904-12 9 p.

    Research output: Contribution to journal › Article › peer-review

  54. Published

    International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma

    Sudhesh Kumar & Keith Wheatley, Sep 2009, In: Leukemia. 23, 9, p. 1545-56 12 p.

    Research output: Contribution to journal › Article › peer-review

  55. Published

    A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin

    Michael Griffiths, 1 Mar 2009, In: Leukemia. 23, 3, p. 614-617 4 p.

    Research output: Contribution to journal › Article

  56. Published

    Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2.

    McNeill Hayden, Dickens Pratt, Nick Davies, Farhat Khanim, Mark Drayson & Christopher Bunce, 1 Feb 2009, In: Leukemia. 23, 2, p. 292-304 13 p.

    Research output: Contribution to journal › Article

  57. Published

    International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders

    & 15 others, & Keith Wheatley, Feb 2009, In: Leukemia. 23, 2, p. 215-24 10 p.

    Research output: Contribution to journal › Article › peer-review

  58. 2008
  59. Published

    A novel functional assay using etoposide plus nutlin-3a detects and distinguishes between ATM and TP53 mutations in CLL

    Anna Skowronska, Tatjana Stankovic, 1 Jul 2008, In: Leukemia. 22, 7, p. 1456-1459 4 p.

    Research output: Contribution to journal › Article

  60. 2007
  61. Published

    Highly purified CD38(+) and CD38(-) subclones derived from the same chronic lymphocytic leukemia patient have distinct gene expression signatures despite their monoclonal origin

    Dickens Pratt, 1 Jan 2007, In: Leukemia. in press

    Research output: Contribution to journal › Article

  62. 2006
  63. Published

    The role of the bax gene polymorphism G(-248)A in chronic lymphocytic leukaemia

    Dickens Pratt, 8 Jun 2006, In: Leukemia. 20, p. 1460-1461 2 p.

    Research output: Contribution to journal › Letter

  64. Published

    CD38+ chronic lymphocytic leukaemia cells co-express high levels of ZAP-70 and are functionally distinct from their CD38- counterparts

    Dickens Pratt, 2 Feb 2006, In: Leukemia. 20, p. 743-744 2 p.

    Research output: Contribution to journal › Letter

  65. 2005
  66. Published

    Treatment strategy and long-term results in paediatric patients treated in consecutive UK AML trials

    Keith Wheatley, Robert Hills, 1 Dec 2005, In: Leukemia. 19, p. 2130-2138 9 p.

    Research output: Contribution to journal › Article

  67. Published

    Zoledronate inhibits proliferation and induces apoptosis of imatinib-resistant chronic myeloid leukaemia cells

    Marwan Cheng Kuang Kwok, Nov 2005, In: Leukemia. 19, p. 1896-1904

    Research output: Contribution to journal › Article › peer-review

  68. Published

    Acquired disomy for chromosome 13 is common in AML and associated with FLT3-itd mutations

    Charles Craddock, 20 Oct 2005, In: Leukemia. 19, p. 2355-2358 4 p.

    Research output: Contribution to journal › Article

  69. Published

    Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors

    Charlotte Bradbury, Farhat Khanim, McNeill Hayden, Christopher Bunce, Darren White, Mark Drayson, Charles Craddock & Bryan Turner, 25 Aug 2005, In: Leukemia. 19, 10, p. 1751-1759 9 p.

    Research output: Contribution to journal › Article

  70. Published

    Insights into the multistep transformation process of lymphomas: IgH-associated translocations and tumour suppressor gene mutations in clonally related composite Hodgkin and non-Hodgkin lymphomas

    Tatjana Stankovic, Belinda Austen, 23 Jun 2005, In: Leukemia. 19, p. 1452-1458 7 p.

    Research output: Contribution to journal › Article

  71. 2003
  72. Published

    Prenatal origin of hyperdiploid acute lymphoblastic leukemia in identical twins

    Michael Griffiths, 1 Nov 2003, In: Leukemia. 17, 11, p. 2202-2206 5 p.

    Research output: Contribution to journal › Article

  73. Published

    Fibrates and medroxyprogesterone acetate induce apoptosis of primary Burkitt’s lymphoma cells and cell lines: potential for applying old drugs to a new disease

    John Gordon, Mark Drayson & Christopher Bunce, 1 Mar 2003, In: Leukemia. 17, 3, p. 568-575 8 p.

    Research output: Contribution to journal › Article

  74. 2002
  75. Published

    An unrelated cytogenetic karyotype and intra-lineage shift at relapse of an aggressive paediatric B-precursor ALL

    Victoria Weston, Tatjana Stankovic, Mark Drayson, 6 Nov 2002, In: Leukemia. 16, 11, p. 2337-2339 3 p.

    Research output: Contribution to journal › Article

  76. Published

    Clinical features, cytogenetics and outcome in acute lymphoblastic and myeloid leukaemia of infancy: report from the MRC Childhood Leukaemia working party

    Keith Wheatley, 2 May 2002, In: Leukemia. 16, 5, p. 776-784 9 p.

    Research output: Contribution to journal › Article

  77. 2001
  78. Published

    Inappropriate reporting and interpretation of subgroups in the AML-BFM 93 study

    Keith Wheatley & Robert Hills, 1 Nov 2001, In: Leukemia. 15, 11, p. 1803-1804 2 p.

    Research output: Contribution to journal › Article

  79. 2000
  80. Published

    A phase I/II study of multiple-dose intravenous busulfan as myeloablation prior to stem cell transplantation

    Charles Craddock, 2000, In: Leukemia. 14, 11, p. 1954-1959 6 p.

    Research output: Contribution to journal › Article

  81. 1994
  82. Published

    Indomethacin potentiates the induction of HL60 differentiation to neutrophils, by retinoic acid and granulocyte colony-stimulating factor, and to monocytes, by vitamin D3

    Christopher Bunce & Geoff Brown, 1 Jan 1994, In: Leukemia. 8, 4, p. 595-604 10 p.

    Research output: Contribution to journal › Article › peer-review

  83. 1992
  84. Published

    Intensive chemotherapy with or without additional bone marrow transplantation in paediatric AML: Progress report on the MRC AML 10 trial

    Keith Wheatley, Richard Gray & 9 others, , Jun 1992, In: Leukemia. 6, SUPPL. 2, p. 55-58 4 p.

    Research output: Contribution to journal › Article › peer-review