Journal of Medicinal Chemistry, ‎0022-2623

Journal

1 - 10 out of 36Page size: 10

Publications

  1. 2021
  2. Published

    Discovery of novel thiophene-arylamide derivatives as DprE1 inhibitors with potent antimycobacterial activities

    Sarah Batt, , , , , , Del Besra & , 13 May 2021, In: Journal of Medicinal Chemistry. 64, 9, p. 6241-6261 21 p.

    Research output: Contribution to journal › Article › peer-review

  3. 2020
  4. E-pub ahead of print

    Discovery of highly selective inhibitors of calmodulin-dependent kinases that restore insulin sensitivity in the diet-induced obese in vivo mouse model

    Graziella Greco, Marc Lenoir, Clare Box, Vera Novitskaya & 14 others, , , , , Steven Vickers, , , , Michael Overduin, Fedor Berditchevski, Chris Weston, , & Sam Butterworth, 20 May 2020, (E-pub ahead of print) In: Journal of Medicinal Chemistry.

    Research output: Contribution to journal › Article › peer-review

  5. Published

    Investigation of inactive state κ opioid receptor homodimerization via single molecule microscopy using new antagonistic fluorescent probes

    Zsombor Koszegi, Yann Lanoiselee, , , Davide Calebiro & , 9 Apr 2020, In: Journal of Medicinal Chemistry. 63, 7, p. 3596-3609 14 p.

    Research output: Contribution to journal › Article › peer-review

  6. 2019
  7. Published

    Design, synthesis and biological evaluation of a new series of carvedilol derivatives that protect sensory hair cells from aminoglycoside-induced damage by blocking the mechano-electrical transducer channel

    Molly O'Reilly, , , , , , , , & , 13 Jun 2019, In: Journal of Medicinal Chemistry. 62, 11, p. 5312-5329 18 p.

    Research output: Contribution to journal › Article › peer-review

  8. Published

    Binding to an unusual inactive kinase conformation by highly selective to inhibitors of inositol-requiring enzyme 1ɑ kinase-endoribonuclease

    Alan M Jones & 1 others, , 1 Mar 2019, In: Journal of Medicinal Chemistry. 62, 5, p. 2447-2465 19 p.

    Research output: Contribution to journal › Article › peer-review

  9. 2018
  10. Published

    In vivo selectivity and localization of reactive oxygen species (ROS) induction by osmium anticancer complexes that circumvent platinum resistance

    Isolda Romero-Canelón, 25 Oct 2018, In: Journal of Medicinal Chemistry. 61, 20, p. 9246–9255 10 p.

    Research output: Contribution to journal › Article › peer-review

  11. Published

    Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a g-quadruplex-binding small molecule

    Jeremy Pike & 3 others, , & , 22 Mar 2018, In: Journal of Medicinal Chemistry. 61, 6, p. 2500-2517 18 p.

    Research output: Contribution to journal › Article › peer-review

  12. Published

    Synthesis and Biological Evaluation of (E)-4-Hydroxy-3-Methylbut-2-enyl Phosphate (HMBP) Aryloxy Triester Phosphoramidate Prodrugs as Activators of Vγ9/Vδ2 T-Cells Immune Response

    Martin Davey, , , , Taher Taher, , Benjamin Willcox & Youcef Mehellou, 19 Feb 2018, In: Journal of Medicinal Chemistry. 61, 5, p. 2111-2117

    Research output: Contribution to journal › Article › peer-review

  13. Published

    BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease

    Giovanni Bottegoni, & , 8 Feb 2018, In: Journal of Medicinal Chemistry. 61, 3, p. 619-637 19 p.

    Research output: Contribution to journal › Review article › peer-review

  14. 2017
  15. E-pub ahead of print

    Quinazolinone-based Anticancer Agents: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Tubulin Co-crystal Structure

    Paul Foster, , , , , , , & , 11 Dec 2017, (E-pub ahead of print) In: Journal of Medicinal Chemistry.

    Research output: Contribution to journal › Article › peer-review

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