Journal of Medicinal Chemistry, 0022-2623

Journal

1 - 10 out of 35Page size: 10

Publications

  1. 2020
  2. E-pub ahead of print

    Discovery of highly selective inhibitors of calmodulin-dependent kinases that restore insulin sensitivity in the diet-induced obese in vivo mouse model

    Graziella Greco, Marc Lenoir, Clare Box, Vera Novitskaya & 14 others, , Steven Vickers, Michael Overduin, Fedor Berditchevski, Christopher Weston & Sam Butterworth, 20 May 2020, In : Journal of Medicinal Chemistry.

    Research output: Contribution to journal › Article

  3. Published

    Investigation of inactive state κ opioid receptor homodimerization via single molecule microscopy using new antagonistic fluorescent probes

    Zsombor Koszegi, Yann Lanoiselee, Davide Calebiro, 9 Apr 2020, In : Journal of Medicinal Chemistry. 63, 7, p. 3596-3609 14 p.

    Research output: Contribution to journal › Article

  4. 2019
  5. Published

    Design, synthesis and biological evaluation of a new series of carvedilol derivatives that protect sensory hair cells from aminoglycoside-induced damage by blocking the mechano-electrical transducer channel

    Molly O'Reilly, 13 Jun 2019, In : Journal of Medicinal Chemistry. 62, 11, p. 5312-5329 18 p.

    Research output: Contribution to journal › Article

  6. Published

    Binding to an unusual inactive kinase conformation by highly selective to inhibitors of inositol-requiring enzyme 1ɑ kinase-endoribonuclease

    Alan M Jones & 1 others, , 1 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2447-2465 19 p.

    Research output: Contribution to journal › Article

  7. 2018
  8. Published

    In vivo selectivity and localization of reactive oxygen species (ROS) induction by osmium anticancer complexes that circumvent platinum-resistance

    Isolda Romero-Canelón, 25 Oct 2018, In : Journal of Medicinal Chemistry. 61, 20, p. 9246–9255

    Research output: Contribution to journal › Article

  9. Published

    Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a g-quadruplex-binding small molecule

    Jeremy Pike & 3 others, , 22 Mar 2018, In : Journal of Medicinal Chemistry. 61, 6, p. 2500-2517 18 p.

    Research output: Contribution to journal › Article

  10. Published

    Synthesis and Biological Evaluation of (E)-4-Hydroxy-3-Methylbut-2-enyl Phosphate (HMBP) Aryloxy Triester Phosphoramidate Prodrugs as Activators of Vγ9/Vδ2 T-Cells Immune Response

    Martin Davey, Taher Taher, Benjamin Willcox & Youcef Mehellou, 19 Feb 2018, In : Journal of Medicinal Chemistry. 61, 5, p. 2111-2117

    Research output: Contribution to journal › Article

  11. Published

    BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease

    Giovanni Bottegoni, 8 Feb 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 619-637 19 p.

    Research output: Contribution to journal › Review article

  12. 2017
  13. E-pub ahead of print

    Quinazolinone-based Anticancer Agents: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Tubulin Co-crystal Structure

    Paul Foster, 11 Dec 2017, In : Journal of Medicinal Chemistry.

    Research output: Contribution to journal › Article

  14. E-pub ahead of print

    The ProTide Prodrug Technology: From the Concept to the Clinic

    Youcef Mehellou, 9 Aug 2017, In : Journal of Medicinal Chemistry.

    Research output: Contribution to journal › Article

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