X-ray fluorescence and the study of microcirculation

P Muthuvelu; Richard Hugtenburg; DA Bradley; CP Winlove

doi:10.1016/S0168-583X(03)01630-6

X-ray fluorescence and the study of microcirculation

P Muthuvelu, Richard Hugtenburg, DA Bradley, CP Winlove

Physics and Astronomy

Research output: Contribution to journal › Article

Abstract

The feasibility of using K-shell X-ray fluorescence (XRF) technique for study of subchondral bone microcirculation in ex vivo samples is examined. Studies have been carried out at the Daresbury Laboratory Synchrotron Radiation Source (SRS) ultra-dilute extended X-ray absorption fine structure beamline. Initial investigations were made on fine-bore capillaries with diameters of either 500 or 200 pm, attenuated by up to 2 turn of Perspex and containing dilute iodine-based contrast media. This allowed comparison to be made with the capabilities of angiographic imaging systems, also allowing definition of suitable XRF set-up parameters for subsequent microcirculation studies. Measurements were obtained in 30 s run times, for concentrations of iodine (K-ab 33.164 keV) down to

Original language	English
Pages (from-to)	548-551
Number of pages	4
Journal	Nuclear Instruments & Methods in Physics Research. Section B. Beam Interactions With Materials and Atoms
Volume	213
DOIs	https://doi.org/10.1016/S0168-583X(03)01630-6
Publication status	Published - 1 Jan 2004

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title = "X-ray fluorescence and the study of microcirculation",

abstract = "The feasibility of using K-shell X-ray fluorescence (XRF) technique for study of subchondral bone microcirculation in ex vivo samples is examined. Studies have been carried out at the Daresbury Laboratory Synchrotron Radiation Source (SRS) ultra-dilute extended X-ray absorption fine structure beamline. Initial investigations were made on fine-bore capillaries with diameters of either 500 or 200 pm, attenuated by up to 2 turn of Perspex and containing dilute iodine-based contrast media. This allowed comparison to be made with the capabilities of angiographic imaging systems, also allowing definition of suitable XRF set-up parameters for subsequent microcirculation studies. Measurements were obtained in 30 s run times, for concentrations of iodine (K-ab 33.164 keV) down to ",

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AU - Muthuvelu, P

AU - Hugtenburg, Richard

AU - Bradley, DA

AU - Winlove, CP

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Y1 - 2004/1/1

N2 - The feasibility of using K-shell X-ray fluorescence (XRF) technique for study of subchondral bone microcirculation in ex vivo samples is examined. Studies have been carried out at the Daresbury Laboratory Synchrotron Radiation Source (SRS) ultra-dilute extended X-ray absorption fine structure beamline. Initial investigations were made on fine-bore capillaries with diameters of either 500 or 200 pm, attenuated by up to 2 turn of Perspex and containing dilute iodine-based contrast media. This allowed comparison to be made with the capabilities of angiographic imaging systems, also allowing definition of suitable XRF set-up parameters for subsequent microcirculation studies. Measurements were obtained in 30 s run times, for concentrations of iodine (K-ab 33.164 keV) down to

AB - The feasibility of using K-shell X-ray fluorescence (XRF) technique for study of subchondral bone microcirculation in ex vivo samples is examined. Studies have been carried out at the Daresbury Laboratory Synchrotron Radiation Source (SRS) ultra-dilute extended X-ray absorption fine structure beamline. Initial investigations were made on fine-bore capillaries with diameters of either 500 or 200 pm, attenuated by up to 2 turn of Perspex and containing dilute iodine-based contrast media. This allowed comparison to be made with the capabilities of angiographic imaging systems, also allowing definition of suitable XRF set-up parameters for subsequent microcirculation studies. Measurements were obtained in 30 s run times, for concentrations of iodine (K-ab 33.164 keV) down to

UR - https://www.scopus.com/pages/publications/0242578351

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DO - 10.1016/S0168-583X(03)01630-6

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JO - Nuclear Instruments & Methods in Physics Research. Section B. Beam Interactions With Materials and Atoms

JF - Nuclear Instruments & Methods in Physics Research. Section B. Beam Interactions With Materials and Atoms

ER -

X-ray fluorescence and the study of microcirculation

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