TY - JOUR
T1 - X-ray fluorescence and the study of microcirculation
AU - Muthuvelu, P
AU - Hugtenburg, Richard
AU - Bradley, DA
AU - Winlove, CP
PY - 2004/1/1
Y1 - 2004/1/1
N2 - The feasibility of using K-shell X-ray fluorescence (XRF) technique for study of subchondral bone microcirculation in ex vivo samples is examined. Studies have been carried out at the Daresbury Laboratory Synchrotron Radiation Source (SRS) ultra-dilute extended X-ray absorption fine structure beamline. Initial investigations were made on fine-bore capillaries with diameters of either 500 or 200 pm, attenuated by up to 2 turn of Perspex and containing dilute iodine-based contrast media. This allowed comparison to be made with the capabilities of angiographic imaging systems, also allowing definition of suitable XRF set-up parameters for subsequent microcirculation studies. Measurements were obtained in 30 s run times, for concentrations of iodine (K-ab 33.164 keV) down to
AB - The feasibility of using K-shell X-ray fluorescence (XRF) technique for study of subchondral bone microcirculation in ex vivo samples is examined. Studies have been carried out at the Daresbury Laboratory Synchrotron Radiation Source (SRS) ultra-dilute extended X-ray absorption fine structure beamline. Initial investigations were made on fine-bore capillaries with diameters of either 500 or 200 pm, attenuated by up to 2 turn of Perspex and containing dilute iodine-based contrast media. This allowed comparison to be made with the capabilities of angiographic imaging systems, also allowing definition of suitable XRF set-up parameters for subsequent microcirculation studies. Measurements were obtained in 30 s run times, for concentrations of iodine (K-ab 33.164 keV) down to
UR - http://www.scopus.com/inward/record.url?scp=0242578351&partnerID=8YFLogxK
U2 - 10.1016/S0168-583X(03)01630-6
DO - 10.1016/S0168-583X(03)01630-6
M3 - Article
VL - 213
SP - 548
EP - 551
JO - Nuclear Instruments & Methods in Physics Research. Section B. Beam Interactions With Materials and Atoms
JF - Nuclear Instruments & Methods in Physics Research. Section B. Beam Interactions With Materials and Atoms
ER -