Which parameters affect biofilm removal with acoustic cavitation? a review

Nina Vyas, K. Manmi, Qian Wang, A. J. Jadhav, Rachel Sammons, M. Barigou, R. L. Sammons, Sarah Kuehne, Anthony Walmsley

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)
455 Downloads (Pure)


Bacterial biofilms are a cause of contamination in a wide range of medical and biological areas. Ultrasound is a mechanical energy that can remove these biofilms using cavitation and acoustic streaming, which generates shear forces to disrupt biofilm from its surface. The aim of this narrative review is to investigate the literature on the mechanical removal of biofilm using acoustic cavitation to identify the different operating parameters affecting its removal using this method. The properties of the liquid and the properties of the ultrasound have a large impact on the type of cavitation generated. These include gas content, temperature, surface tension, frequency of ultrasound and acoustic pressure. Many of these parameters require more research to understand their mechanisms in the area of ultrasonic biofilm removal and further research will help to optimise this method for effective removal of biofilms from different surfaces.
Original languageEnglish
Pages (from-to)1044-1055
JournalUltrasound in Medicine & Biology
Issue number5
Early online date19 Feb 2019
Publication statusPublished - 1 May 2019


  • biofilm cavitation
  • biofilm removal
  • ultrasonic cleaning


Dive into the research topics of 'Which parameters affect biofilm removal with acoustic cavitation? a review'. Together they form a unique fingerprint.

Cite this