Which gait parameters and walking patterns show the significant differences between Parkinson’s disease and healthy participants?

Sana M. Keloth, Rekha Viswanathan, Beth Jelfs, Sridhar Arjunan, Sanjay Raghav, Dinesh Kumar

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

This study investigated the difference in the gait of patients with Parkinson’s disease (PD), age-matched controls and young controls during three walking patterns. Experiments were conducted with 24 PD, 24 age-matched controls and 24 young controls, and four gait intervals were measured using inertial measurement units (IMU). Group differences between the mean and variance of the gait parameters (stride interval, stance interval, swing interval and double support interval) for the three groups were calculated and statistical significance was tested. The results showed that the variance in each of the four gait parameters of PD patients was significantly higher compared with the controls, irrespective of the three walking patterns. This study showed that the variance of any of the gait interval parameters obtained using IMU during any of the walking patterns could be used to differentiate between the gait of PD and control people.

Original languageEnglish
Article number59
JournalBiosensors
Volume9
Issue number2
DOIs
Publication statusPublished - 1 Jun 2019
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2019 by the authors.

Keywords

  • Gait
  • IMU
  • Parkinson’s disease
  • Variance

ASJC Scopus subject areas

  • Clinical Biochemistry

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