What makes Cryptococcus gattii a pathogen?

Ewa Bielska, Robin C May

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)
114 Downloads (Pure)

Abstract

Cryptococcosis is an invasive fungal infection of humans and other animals, typically caused by the species Cryptococcus neoformans in patients with impaired immunity. However, there is growing recognition of the importance of the related species C. gattii in causing infections in apparently immunocompetent individuals. In particular, an ongoing outbreak of cryptococcal disease in the Pacific Northwest region, which started in 1999, has driven an intense research effort into this previously neglected pathogen. Here, we discuss some of the recent discoveries in this organism from the Pacific Northwest region and highlight areas for future investigation.

Original languageEnglish
JournalFEMS yeast research
Volume16
Issue number1
Early online date26 Nov 2015
DOIs
Publication statusPublished - Feb 2016

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