Abstract
Metal-on-polyethylene total disc replacements have been an alternative to spinal fusion in the lumbar spine under certain indications for more than a decade. Recently, cervical total disc replacement has also become an alternative to cervical fusion. Knowledge acquired from years of in vitro simulator studies on other joint replacements has highlighted the risks associated with premature wear due to unforeseen adverse clinical conditions and the effect of particulate debris on surrounding natural tissues. Having no evidence of the type and composition of the lubricating fluid that will result after spinal arthroplasty, a study on the effects of lubricant serum concentration was undertaken. The wear rate was shown to be inversely proportional to protein content of the serum over a range of 50%-3% bovine serum to water concentration.
| Original language | English |
|---|---|
| Pages (from-to) | 481-488 |
| Number of pages | 8 |
| Journal | Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine |
| Volume | 230 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 2016 |
Bibliographical note
Funding Information:The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: John Fisher is an NIHR senior investigator and supported through NIHR LMBRU Leeds Biomedical Musculoskeletal Research Unit. Philip Hyde, Professor Fisher and Professor Hall are supported through the Leeds Centre of Excellence in Medical Engineering, WELMEC, funded by the Wellcome Trust and EPSRC, WT 088908/Z/09/Z.
Publisher Copyright:
© IMechE 2016.
Keywords
- cervical
- disc
- serum
- simulation
- spine
- total disc replacement
- Tribology
- wear
ASJC Scopus subject areas
- Mechanical Engineering