Abstract
It is almost 30 years since an interaction between vitamin D and the immune system was first documented. Although this was initially proposed as a nonclassic effect of vitamin D associated with granulomatous diseases, our current view is now changed considerably. Recent studies have shown a potential physiologic role for vitamin D in regulating normal innate and adaptive immunity. Future studies now need to focus on the clinical implications of vitamin D–mediated immunity and, in particular, the possible beneficial effects of supplementary vitamin D with respect to infectious and autoimmune diseases.
Original language | English |
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Pages (from-to) | 125-39 |
Number of pages | 15 |
Journal | Rheumatic Diseases Clinics of North America |
Volume | 38 |
Issue number | 1 |
DOIs | |
Publication status | Published - Feb 2012 |