Vitamin D and the immune system: new perspectives on an old theme

Research output: Contribution to journalArticlepeer-review

84 Citations (Scopus)


It is almost 30 years since an interaction between vitamin D and the immune system was first documented. Although this was initially proposed as a nonclassic effect of vitamin D associated with granulomatous diseases, our current view is now changed considerably. Recent studies have shown a potential physiologic role for vitamin D in regulating normal innate and adaptive immunity. Future studies now need to focus on the clinical implications of vitamin D–mediated immunity and, in particular, the possible beneficial effects of supplementary vitamin D with respect to infectious and autoimmune diseases.

Original languageEnglish
Pages (from-to)125-39
Number of pages15
JournalRheumatic Diseases Clinics of North America
Issue number1
Publication statusPublished - Feb 2012

Bibliographical note

Copyright © 2012 Elsevier Inc. All rights reserved.


Dive into the research topics of 'Vitamin D and the immune system: new perspectives on an old theme'. Together they form a unique fingerprint.

Cite this