TY - JOUR
T1 - Vitamin D and systemic lupus erythematosus - the hype and the hope
AU - Shoenfeld, Yehuda
AU - Giacomelli, Roberto
AU - Azrielant, Shir
AU - Berardicurti, Onorina
AU - Reynolds, John A.
AU - Bruce, Ian N.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Over the past 20 years, much has been written about the potential role of vitamin D in on adverse health outcomes. In recent years, evidence has accumulated regarding the effect of vitamin D on the immune system, and its different cells. Some studies have noted lower vitamin D concentrations in patients with SLE. These epidemiological data still not answer the question: is vitamin D deficiency the cause or the effect? To answer this, we will discuss the association between vitamin D deficiency and SLE and review the evidence from interventional studies.
AB - Over the past 20 years, much has been written about the potential role of vitamin D in on adverse health outcomes. In recent years, evidence has accumulated regarding the effect of vitamin D on the immune system, and its different cells. Some studies have noted lower vitamin D concentrations in patients with SLE. These epidemiological data still not answer the question: is vitamin D deficiency the cause or the effect? To answer this, we will discuss the association between vitamin D deficiency and SLE and review the evidence from interventional studies.
KW - SLE
KW - Systemic lupus erythematosus
KW - Vitamin D
KW - Vitamin D deficiency
UR - http://www.scopus.com/inward/record.url?scp=85034643933&partnerID=8YFLogxK
UR - https://www.research.manchester.ac.uk/portal/en/publications/vitamin-d-and-systemic-lupus-erythematosus--the-hype-and-the-hope(ff5f2d7b-4858-476b-8cd6-4799a4468dab).html
U2 - 10.1016/j.autrev.2017.11.004
DO - 10.1016/j.autrev.2017.11.004
M3 - Review article
C2 - 29108830
AN - SCOPUS:85034643933
SN - 1568-9972
VL - 17
SP - 19
EP - 23
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
IS - 1
ER -