Visualization of the in vivo generation of donor antigen-specific effector CD8+ T cells during mouse cardiac allograft rejection: in vivo effector CD8+ T cell generation during allograft rejection

B J Gilot; M Hara; N D Jones; A van Maurik; M Niimi; V Hadjianastassiou; P J Morris; K J Wood

Visualization of the in vivo generation of donor antigen-specific effector CD8+ T cells during mouse cardiac allograft rejection: in vivo effector CD8+ T cell generation during allograft rejection

B J Gilot
, M Hara
, N D Jones
, A van Maurik
, M Niimi
, V Hadjianastassiou
, P J Morris
, K J Wood

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

An adoptive transfer system was used to study the fate of alloreactive CD8+ H-2Kb-specific TCR transgenic (DES+) T cells in vivo after transplantation.

Original language	English
Pages (from-to)	639-48
Number of pages	10
Journal	Transplantation
Volume	69
Issue number	4
Publication status	Published - 27 Feb 2000

Keywords

Animals
Tetradecanoylphorbol Acetate
Interferon-gamma
Heart Transplantation
Histocompatibility Antigens Class I
Lymphocyte Culture Test, Mixed
Mice
Transplantation, Homologous
Mice, Transgenic
Mice, Inbred BALB C
CD4-Positive T-Lymphocytes
Tissue Donors
Mice, Inbred CBA
Adoptive Transfer
Graft Rejection
CD8-Positive T-Lymphocytes
Graft Survival
Ionomycin
Mice, Inbred C57BL
Cytokines
Flow Cytometry
Epitopes
Cell Division

Cite this

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title = "Visualization of the in vivo generation of donor antigen-specific effector CD8+ T cells during mouse cardiac allograft rejection: in vivo effector CD8+ T cell generation during allograft rejection",

abstract = "An adoptive transfer system was used to study the fate of alloreactive CD8+ H-2Kb-specific TCR transgenic (DES+) T cells in vivo after transplantation.",

keywords = "Animals, Tetradecanoylphorbol Acetate, Interferon-gamma, Heart Transplantation, Histocompatibility Antigens Class I, Lymphocyte Culture Test, Mixed, Mice, Transplantation, Homologous, Mice, Transgenic, Mice, Inbred BALB C, CD4-Positive T-Lymphocytes, Tissue Donors, Mice, Inbred CBA, Adoptive Transfer, Graft Rejection, CD8-Positive T-Lymphocytes, Graft Survival, Ionomycin, Mice, Inbred C57BL, Cytokines, Flow Cytometry, Epitopes, Cell Division",

author = "Gilot, \{B J\} and M Hara and Jones, \{N D\} and \{van Maurik\}, A and M Niimi and V Hadjianastassiou and Morris, \{P J\} and Wood, \{K J\}",

year = "2000",

month = feb,

day = "27",

language = "English",

volume = "69",

pages = "639--48",

journal = "Transplantation",

issn = "0041-1337",

publisher = "Lippincott Williams and Wilkins",

number = "4",

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TY - JOUR

T1 - Visualization of the in vivo generation of donor antigen-specific effector CD8+ T cells during mouse cardiac allograft rejection

T2 - in vivo effector CD8+ T cell generation during allograft rejection

AU - Gilot, B J

AU - Hara, M

AU - Jones, N D

AU - van Maurik, A

AU - Niimi, M

AU - Hadjianastassiou, V

AU - Morris, P J

AU - Wood, K J

PY - 2000/2/27

Y1 - 2000/2/27

N2 - An adoptive transfer system was used to study the fate of alloreactive CD8+ H-2Kb-specific TCR transgenic (DES+) T cells in vivo after transplantation.

AB - An adoptive transfer system was used to study the fate of alloreactive CD8+ H-2Kb-specific TCR transgenic (DES+) T cells in vivo after transplantation.

KW - Animals

KW - Tetradecanoylphorbol Acetate

KW - Interferon-gamma

KW - Heart Transplantation

KW - Histocompatibility Antigens Class I

KW - Lymphocyte Culture Test, Mixed

KW - Mice

KW - Transplantation, Homologous

KW - Mice, Transgenic

KW - Mice, Inbred BALB C

KW - CD4-Positive T-Lymphocytes

KW - Tissue Donors

KW - Mice, Inbred CBA

KW - Adoptive Transfer

KW - Graft Rejection

KW - CD8-Positive T-Lymphocytes

KW - Graft Survival

KW - Ionomycin

KW - Mice, Inbred C57BL

KW - Cytokines

KW - Flow Cytometry

KW - Epitopes

KW - Cell Division

M3 - Article

C2 - 10708123

SN - 0041-1337

VL - 69

SP - 639

EP - 648

JO - Transplantation

JF - Transplantation

IS - 4

ER -

Visualization of the in vivo generation of donor antigen-specific effector CD8+ T cells during mouse cardiac allograft rejection: in vivo effector CD8+ T cell generation during allograft rejection

Abstract

Keywords

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