Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

Mark R. Viant; Timothy M.D. Ebbels; Richard D. Beger; Drew R. Ekman; David J.T. Epps; Hennicke Kamp; Pim E.G. Leonards; George D. Loizou; James I. MacRae; Bennard van Ravenzwaay; Philippe Rocca-Serra; Reza M. Salek; Tilmann Walk; Ralf J.M. Weber

doi:10.1038/s41467-019-10900-y

Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

Mark R. Viant^*, Timothy M.D. Ebbels, Richard D. Beger, Drew R. Ekman, David J.T. Epps, Hennicke Kamp, Pim E.G. Leonards, George D. Loizou, James I. MacRae, Bennard van Ravenzwaay, Philippe Rocca-Serra, Reza M. Salek, Tilmann Walk, Ralf J.M. Weber

^*Corresponding author for this work

Biosciences

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

Lack of best practice guidelines currently limits the application of metabolomics in the regulatory sciences. Here, the MEtabolomics standaRds Initiative in Toxicology (MERIT) proposes methods and reporting standards for several important applications of metabolomics in regulatory toxicology.

Original language	English
Article number	3041
Journal	Nature Communications
Volume	10
Issue number	1
DOIs	https://doi.org/10.1038/s41467-019-10900-y
Publication status	Published - 1 Dec 2019

ASJC Scopus subject areas

General Chemistry
General Biochemistry,Genetics and Molecular Biology
General Physics and Astronomy

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Viant, M. R., Ebbels, T. M. D., Beger, R. D., Ekman, D. R., Epps, D. J. T., Kamp, H., Leonards, P. E. G., Loizou, G. D., MacRae, J. I., van Ravenzwaay, B., Rocca-Serra, P., Salek, R. M., Walk, T., & Weber, R. J. M. (2019). Use cases, best practice and reporting standards for metabolomics in regulatory toxicology. Nature Communications, 10(1), Article 3041. https://doi.org/10.1038/s41467-019-10900-y

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Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

Abstract

ASJC Scopus subject areas

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