Update on De-intensification and Intensification Studies in HPV

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Citations (Scopus)


In this chapter, we discuss de-esclation of treatment for patients with HPV-positive disease. We discuss the rationale for de-escalation (why de-escalate?), patient selection criteria (who to de-esclate?) and what the treatment options for de-esclation are and the studies that are currently being run in those areas (how to de-escalate?). We stress the importance of clinicians NOT changing the management of oropharyngeal cancer patients outside clinical trials, and encourage them to recruit to the ongoing studies.

Original languageEnglish
Title of host publicationHPV Infection in Head and Neck Cancer
EditorsW Goluscinski, C.R Leemans, A Dietz
Place of PublicationNew York
Number of pages6
ISBN (Electronic)978-3-319-43580-0
ISBN (Print)978-3-319-43578-7
Publication statusE-pub ahead of print - 4 Oct 2016

Publication series

NameRecent Results in Cancer Research
ISSN (Print)0080-0015
ISSN (Electronic)2197-6767


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