Unravelling mechanisms that govern meiotic crossover formation in wheat

James D. Higgins; Kim Osman; Stuart D. Desjardins; Ian Henderson; Keith J. Edwards; F. Chris H. Franklin

doi:10.1042/BST20220405

Unravelling mechanisms that govern meiotic crossover formation in wheat

James D. Higgins, Kim Osman, Stuart D. Desjardins, Ian Henderson, Keith J. Edwards, F. Chris H. Franklin

Research output: Contribution to journal › Review article › peer-review

82 Downloads (Pure)

Abstract

Wheat is a major cereal crop that possesses a large allopolyploid genome formed through hybridisation of tetraploid and diploid progenitors. During meiosis, crossovers (COs) are constrained in number to 1–3 per chromosome pair that are predominantly located towards the chromosome ends. This reduces the probability of advantageous traits recombining onto the same chromosome, thus limiting breeding. Therefore, understanding the underlying factors controlling meiotic recombination may provide strategies to unlock the genetic potential in wheat. In this mini-review, we will discuss the factors associated with restricted CO formation in wheat, such as timing of meiotic events, chromatin organisation, pre-meiotic DNA replication and dosage of CO genes, as a means to modulate recombination.

Original language	English
Article number	BST20220405
Pages (from-to)	1179-1186
Number of pages	8
Journal	Biochemical Society Transactions
Volume	50
Issue number	4
DOIs	https://doi.org/10.1042/BST20220405
Publication status	Published - 28 Jul 2022

Keywords

crossover
meiosis
recombination
wheat

Access to Document

10.1042/BST20220405Licence: Creative Commons: Attribution (CC BY)

higginsj2022unravellingFinal published version, 831 KBLicence: Creative Commons: Attribution (CC BY)

Releasing natural variation in bread wheat by modulating meiotic crossovers (BB/N002628/1) (BISC.RA0678)
Sanchez-Moran, E. (Principal Investigator)
Biotechnology & Biological Sciences Research Council
1/01/16 → 31/12/20
Project: Research Councils

Cite this

@article{7378382a91d64b5081ed824790ccbf5d,

title = "Unravelling mechanisms that govern meiotic crossover formation in wheat",

abstract = "Wheat is a major cereal crop that possesses a large allopolyploid genome formed through hybridisation of tetraploid and diploid progenitors. During meiosis, crossovers (COs) are constrained in number to 1–3 per chromosome pair that are predominantly located towards the chromosome ends. This reduces the probability of advantageous traits recombining onto the same chromosome, thus limiting breeding. Therefore, understanding the underlying factors controlling meiotic recombination may provide strategies to unlock the genetic potential in wheat. In this mini-review, we will discuss the factors associated with restricted CO formation in wheat, such as timing of meiotic events, chromatin organisation, pre-meiotic DNA replication and dosage of CO genes, as a means to modulate recombination. ",

keywords = "crossover, meiosis, recombination, wheat",

author = "Higgins, {James D.} and Kim Osman and Desjardins, {Stuart D.} and Ian Henderson and Edwards, {Keith J.} and Franklin, {F. Chris H.}",

year = "2022",

month = jul,

day = "28",

doi = "10.1042/BST20220405",

language = "English",

volume = "50",

pages = "1179--1186",

journal = "Biochemical Society Transactions",

issn = "1470-8752",

publisher = "Portland Press",

number = "4",

}

TY - JOUR

T1 - Unravelling mechanisms that govern meiotic crossover formation in wheat

AU - Higgins, James D.

AU - Osman, Kim

AU - Desjardins, Stuart D.

AU - Henderson, Ian

AU - Edwards, Keith J.

AU - Franklin, F. Chris H.

PY - 2022/7/28

Y1 - 2022/7/28

N2 - Wheat is a major cereal crop that possesses a large allopolyploid genome formed through hybridisation of tetraploid and diploid progenitors. During meiosis, crossovers (COs) are constrained in number to 1–3 per chromosome pair that are predominantly located towards the chromosome ends. This reduces the probability of advantageous traits recombining onto the same chromosome, thus limiting breeding. Therefore, understanding the underlying factors controlling meiotic recombination may provide strategies to unlock the genetic potential in wheat. In this mini-review, we will discuss the factors associated with restricted CO formation in wheat, such as timing of meiotic events, chromatin organisation, pre-meiotic DNA replication and dosage of CO genes, as a means to modulate recombination.

AB - Wheat is a major cereal crop that possesses a large allopolyploid genome formed through hybridisation of tetraploid and diploid progenitors. During meiosis, crossovers (COs) are constrained in number to 1–3 per chromosome pair that are predominantly located towards the chromosome ends. This reduces the probability of advantageous traits recombining onto the same chromosome, thus limiting breeding. Therefore, understanding the underlying factors controlling meiotic recombination may provide strategies to unlock the genetic potential in wheat. In this mini-review, we will discuss the factors associated with restricted CO formation in wheat, such as timing of meiotic events, chromatin organisation, pre-meiotic DNA replication and dosage of CO genes, as a means to modulate recombination.

KW - crossover

KW - meiosis

KW - recombination

KW - wheat

UR - http://www.scopus.com/inward/record.url?scp=85137124806&partnerID=8YFLogxK

U2 - 10.1042/BST20220405

DO - 10.1042/BST20220405

M3 - Review article

C2 - 35901450

SN - 1470-8752

VL - 50

SP - 1179

EP - 1186

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

IS - 4

M1 - BST20220405

ER -

Unravelling mechanisms that govern meiotic crossover formation in wheat

Abstract

Keywords

Access to Document

Fingerprint

Projects

Releasing natural variation in bread wheat by modulating meiotic crossovers (BB/N002628/1) (BISC.RA0678)

Cite this