Uncoupling proteins; targets for endocrine disruptors?

David Ramsden, U Loos

Research output: Contribution to journalArticle

5 Citations (Scopus)


The roles of uncoupling proteins (UCPs) are discussed. Particular attention has been paid to the roles of UCP2 to UCP5 as agents mediating thermogenesis, and to the concept of limited or "mild" uncoupling as a means of reducing oxidative stress. The role of the endocrine system, thyroid hormones and catecholamines, in regulating expression of UCPs is also discussed.
Original languageEnglish
Pages (from-to)79-86
Number of pages8
JournalMolecular and Cellular Endocrinology
Publication statusPublished - 1 Dec 2005


  • uncoupling protein
  • ATP
  • oxidative phosphorylation
  • electron transport


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