Uncertainties in the antibacterial mechanisms of graphene family materials

Peng Zhang, Zhiling Guo*, Chunying Chen, Iseult Lynch

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

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The antibacterial activity of graphene family materials (GFMs) has been explored since 2010, 6 years after the discovery of graphene in 2004. It is proposed that the antibacterial activity is derived from both physical interaction and chemical reaction between GFMs and bacteria. However, whether the two mechanisms work synergistically or whether there are conditions under which one mechanism dominates remains uncertain. This opinion article highlights the uncertainties and controversies in the current understanding of antibacterial mechanisms of GFMs as well as deficiencies in methodologies and provides perspectives on future directions to move this field forward.

Original languageEnglish
Article number101436
JournalNano Today
Early online date21 Feb 2022
Publication statusPublished - Apr 2022

Bibliographical note

Funding Information:
This work was supported by the EU H2020 NanoCommons (Grant Agreement No. 731032 ), EU H2020 NanoSolveIT (Grant Agreement No. 814572 ), EPSRC IAA Developing Leaders (Grant No. 1001634 ), and Major instrument project of National Natural Science Foundation of China ( 22027810 ).


  • Bacteria
  • Computational modelling
  • Graphene family materials
  • Oxidative damage
  • Physical interaction

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering
  • Materials Science(all)
  • Pharmaceutical Science


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