Truncated RON tyrosine kinase drives tumor cell progression and abrogates cell-cell adhesion through E-cadherin transcriptional repression

Keyphrases

• Tumor Cells 100%
• Tyrosine Kinase 100%
• Cell Adhesion 100%
• E-cadherin 100%
• Transcriptional Repression 100%
• Cell Progression 100%
• Cancer Cells 50%
• Leukemia 50%
• Constitutively Active 50%
• Epithelial Cells 50%
• Human Cancer 50%
• Transcription Factor 50%
• Ligand Binding 50%
• Cell Growth 50%
• Ovarian Carcinoma 50%
• Transmembrane Domain 50%
• Monolayer Culture 50%
• Aggressive Behavior 50%
• Gastrointestinal Tract 50%
• Tumor Progression 50%
• Tyrosine Kinase Receptor 50%
• Extracellular Domain 50%
• Truncated Protein 50%
• E-cadherin Expression 50%
• Tyrosine Kinase Activity 50%
• Human Lung 50%
• Epithelial Phenotype 50%
• Aggressive Phenotype 50%
• Ovarian Tissue 50%
• Intracellular Domain 50%
• Anchorage-independent Growth 50%
• Ovarian Cells 50%
• Pancreatic Carcinoma 50%
• Invasive Growth 50%
• Non-epithelial 50%

Biochemistry, Genetics and Molecular Biology

• Cell Adhesion 100%
• Cadherin 100%
• Receptor Tyrosine Kinase 100%
• Drive 100%
• Growth Hormone 100%
• Tyrosine Kinase 100%
• Cancer Cell 50%
• Tumor Progression 50%
• Ligand Binding 50%
• Kinase 50%
• Phosphotransferase 50%
• Messenger RNA 50%
• Tyrosine Kinase Receptor 50%
• Gastrointestinal Tract 50%
• Anchorage Independent Growth 50%
• Monolayer Culture 50%