Trifluoromethyldiazirine: An effective photo-induced cross-linking probe for exploring amyloid formation

David P. Smith; Jon Anderson; Jeffrey Plante; Alison E. Ashcroft; Sheena E. Radford; Andrew J. Wilson; Martin J. Parker

doi:10.1039/b813504e

Trifluoromethyldiazirine: An effective photo-induced cross-linking probe for exploring amyloid formation

David P. Smith
, Jon Anderson
, Jeffrey Plante
, Alison E. Ashcroft
, Sheena E. Radford
, Andrew J. Wilson
, Martin J. Parker

Chemistry

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

The separative and analytical power of ion mobility spectrometry-mass spectrometry combined with photo-induced cross-linking of site-specifically incorporated trifluoromethyldiazirine provides a powerful approach towards structural characterisation of amyloid fibrils.

Original language	English
Pages (from-to)	5728-5730
Number of pages	3
Journal	Chemical Communications
Issue number	44
DOIs	https://doi.org/10.1039/b813504e
Publication status	Published - 2008

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b813504e

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title = "Trifluoromethyldiazirine: An effective photo-induced cross-linking probe for exploring amyloid formation",

abstract = "The separative and analytical power of ion mobility spectrometry-mass spectrometry combined with photo-induced cross-linking of site-specifically incorporated trifluoromethyldiazirine provides a powerful approach towards structural characterisation of amyloid fibrils.",

author = "Smith, \{David P.\} and Jon Anderson and Jeffrey Plante and Ashcroft, \{Alison E.\} and Radford, \{Sheena E.\} and Wilson, \{Andrew J.\} and Parker, \{Martin J.\}",

year = "2008",

doi = "10.1039/b813504e",

language = "English",

pages = "5728--5730",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Trifluoromethyldiazirine

T2 - An effective photo-induced cross-linking probe for exploring amyloid formation

AU - Smith, David P.

AU - Anderson, Jon

AU - Plante, Jeffrey

AU - Ashcroft, Alison E.

AU - Radford, Sheena E.

AU - Wilson, Andrew J.

AU - Parker, Martin J.

PY - 2008

Y1 - 2008

N2 - The separative and analytical power of ion mobility spectrometry-mass spectrometry combined with photo-induced cross-linking of site-specifically incorporated trifluoromethyldiazirine provides a powerful approach towards structural characterisation of amyloid fibrils.

AB - The separative and analytical power of ion mobility spectrometry-mass spectrometry combined with photo-induced cross-linking of site-specifically incorporated trifluoromethyldiazirine provides a powerful approach towards structural characterisation of amyloid fibrils.

UR - https://www.scopus.com/pages/publications/56349141592

U2 - 10.1039/b813504e

DO - 10.1039/b813504e

M3 - Article

C2 - 19009062

AN - SCOPUS:56349141592

SN - 1359-7345

SP - 5728

EP - 5730

JO - Chemical Communications

JF - Chemical Communications

IS - 44

ER -

Trifluoromethyldiazirine: An effective photo-induced cross-linking probe for exploring amyloid formation

Abstract

ASJC Scopus subject areas

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