Trifluoromethyldiazirine: An effective photo-induced cross-linking probe for exploring amyloid formation

David P. Smith, Jon Anderson, Jeffrey Plante, Alison E. Ashcroft, Sheena E. Radford, Andrew J. Wilson, Martin J. Parker

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

The separative and analytical power of ion mobility spectrometry-mass spectrometry combined with photo-induced cross-linking of site-specifically incorporated trifluoromethyldiazirine provides a powerful approach towards structural characterisation of amyloid fibrils.

Original languageEnglish
Pages (from-to)5728-5730
Number of pages3
JournalChemical Communications
Issue number44
DOIs
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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