Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2.

Rachel Hayden, Guy Pratt, Nicholas Davies, Farhat Khanim, J Birtwistle, J Delgado, Claire Pearce, T Sant, Mark Drayson, Christopher Bunce

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Keyphrases

Pharmacology, Toxicology and Pharmaceutical Science

Immunology and Microbiology

Biochemistry, Genetics and Molecular Biology