Transposon mutagenesis of Mb0100 at the ppe1-nrp locus in Mycobacterium bovis disrupts phthiocerol dimycocerosate (PDIM) and glycosylphenol-PDIM biosynthesis, producing an avirulent strain with vaccine properties at least equal to those of M-bovis BCG

GS Hotter, BJ Wards, P Mouat, Gurdyal Besra, J Gomes, M Singh, S Bassatt, O Kawakami, PR Wheeler, GW de Lisle, DM Collins

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Medicine & Life Sciences