TY - CHAP
T1 - Translational biomarkers in the era of precision medicine
AU - Bravo-Merodio, Laura
AU - Acharjee, Animesh
AU - Russ, Dominic
AU - Bisht, Vartika
AU - Williams, John A.
AU - Tsaprouni, Loukia G.
AU - Gkoutos, Georgios V.
N1 - Copyright © 2021 Elsevier Inc. All rights reserved.
PY - 2021
Y1 - 2021
N2 - In this chapter we discuss the past, present and future of clinical biomarker development. We explore the advent of new technologies, paving the way in which health, medicine and disease is understood. This review includes the identification of physicochemical assays, current regulations, the development and reproducibility of clinical trials, as well as, the revolution of omics technologies and state-of-the-art integration and analysis approaches.
AB - In this chapter we discuss the past, present and future of clinical biomarker development. We explore the advent of new technologies, paving the way in which health, medicine and disease is understood. This review includes the identification of physicochemical assays, current regulations, the development and reproducibility of clinical trials, as well as, the revolution of omics technologies and state-of-the-art integration and analysis approaches.
KW - Artificial Intelligence
KW - Biomarkers/analysis
KW - Humans
KW - Precision Medicine
U2 - 10.1016/bs.acc.2020.08.002
DO - 10.1016/bs.acc.2020.08.002
M3 - Chapter
C2 - 34044910
SN - 9780128246146
T3 - Advances in clinical chemistry
SP - 192
EP - 232
BT - Advances in Clinical Chemistry
PB - Elsevier
ER -